KEGG   Mustela putorius furo (domestic ferret): 101673283
Entry
101673283         CDS       T07239                                 
Symbol
APC2
Name
(RefSeq) adenomatous polyposis coli protein 2 isoform X1
  KO
K02085  adenomatosis polyposis coli protein
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf04310  Wnt signaling pathway
mpuf04390  Hippo signaling pathway
mpuf04550  Signaling pathways regulating pluripotency of stem cells
mpuf04810  Regulation of actin cytoskeleton
mpuf04934  Cushing syndrome
mpuf05010  Alzheimer disease
mpuf05022  Pathways of neurodegeneration - multiple diseases
mpuf05165  Human papillomavirus infection
mpuf05200  Pathways in cancer
mpuf05206  MicroRNAs in cancer
mpuf05210  Colorectal cancer
mpuf05213  Endometrial cancer
mpuf05217  Basal cell carcinoma
mpuf05224  Breast cancer
mpuf05225  Hepatocellular carcinoma
mpuf05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    101673283 (APC2)
   04390 Hippo signaling pathway
    101673283 (APC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101673283 (APC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101673283 (APC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101673283 (APC2)
   05206 MicroRNAs in cancer
    101673283 (APC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101673283 (APC2)
   05225 Hepatocellular carcinoma
    101673283 (APC2)
   05226 Gastric cancer
    101673283 (APC2)
   05217 Basal cell carcinoma
    101673283 (APC2)
   05213 Endometrial cancer
    101673283 (APC2)
   05224 Breast cancer
    101673283 (APC2)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    101673283 (APC2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101673283 (APC2)
   05022 Pathways of neurodegeneration - multiple diseases
    101673283 (APC2)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101673283 (APC2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mpuf01009]
    101673283 (APC2)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mpuf03036]
    101673283 (APC2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:mpuf04812]
    101673283 (APC2)
Protein phosphatases and associated proteins [BR:mpuf01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     101673283 (APC2)
Chromosome and associated proteins [BR:mpuf03036]
 Eukaryotic type
  Centrosome formation proteins
   Other centrosome associated proteins
    101673283 (APC2)
Cytoskeleton proteins [BR:mpuf04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    EB / APC
     101673283 (APC2)
SSDB
Motif
Pfam: APC_basic APC_rep APC_N_CC Arm Suppressor_APC APC_r Arm_APC_u3 SAMP ZER1-like_2nd ARM_ARMC5 Sec7-like_HUS ATG16 bZIP_1 Wtap JIP_LZII Sec2p HALZ CCDC138_cc
Other DBs
NCBI-GeneID: 101673283
NCBI-ProteinID: XP_012904214
Ensembl: ENSMPUG00000008189
LinkDB
Position
Unknown
AA seq 2357 aa
MAPGLLPALRLAAAAASRIPHPPPLAVVSPSPRSGGAAWAGRDRALSAPEPSACAAKTPE
TRNPRPAAPPPAQPERDKALQELKMASSVAPYEQLVRQVEALKAENSHLRQELRDNSSHL
SKLETETSGMKEVLKHLQGKLEQEAGVLVSLGQTDVLEQLKALQMDITSLYNLKFQPPAL
SPEPAARTPEESPVHGSGPSKDSFGELSRATVRLLEELDRERCFLLNEIEKEEKEKLWYY
SQLQGLSKRLDELPHVETVSMQMDLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRAS
RLEQIDQELLSAQDRVPQTEAQALLAVKSVPVEEDPETEVPTHPDDGVPQPGNSKVEVVF
WLLSMLATRDQEDTARTLLAMSSSPESCVAMRRSGCLPLLLQILHGAEAGNGSPGAPGAK
DARMRANAALHNIVFSQPDQGLARKEMRVLHVLEQIRAYCETCWDWLRGRDDADGGGEGG
GERAGAPVWGAPVPIEPQICQATCAVMKLSFDEEYRRAMNELGGLQAVADLLQVDYEMHK
MTRDPLNLALRRYAGMTLTNLTFGDVANKATLCARRGCMEAIVAQLASESEELHQVVSSI
LRNLSWRADINSKKVLREVGSMTALMQCVLRASKESTLKSVLSALWNLSAHSTENKAAIC
QVDGALGFLVSTLTHKCQSNSLAIIESGGGILRNVSSLIATREDYRQVLRDHNCLQTLLQ
HLTSHSLTIVSNACGTLWNLSARSPRDQELLWDLGAVGMLRNLVHSKHKMIAMGSAAALR
NLLAHRPAKYQTTATAVSPGACAPSLYVRKQRALEAELDTRHLAQALDHLEKQGLPEAEA
DAASKKPLPPLRHLDGLARDYASDSGCFDDDEAPSLAAVAATAEPASPAVLSLFLGSPFL
QGQALARAPPARRSGPEAEKEASGEVAVAARAKAKLALAVARIDRLVEDISALHTSSDDS
FSLSSGDPGQEAPREGRAQSCSPCRRPEGRRPEAGSRAHPLLRLKAAHASLSNDSLNSGS
TGDGRCPREHTRSCPLAVLAEHREGSPSSQVRPSRLDLHLPGSQEPASRDGSAADACVRT
IKLSPTYQHVPLFEGNPRAGMGSLAPGARKQAWLPMDGLSKVPEKLVAETVPLCLSRCSS
LSSLSSAGRPGPSEAGDLDSDSSLEGLEEAGPSKADLDGAWLGPGAASLPVAIPAPQRGR
GLGVEDTTPSSSSENCVQETPLVLSRCSSVSSLSSFESPSIASSVPSDPCSGLGSGTVSP
SELPDSPGQTMPPSRSKTPPLAPAPPGERESTQFSLQWESYVKRFLDIADRRERCRLPSE
LDAGSVRFTVEKPDENFSCASSLSALALHEHYVQKDVELRLLPPACPEGGGGGGGGGPGL
HFAGHRRRDEAGGCLEGPAATDQELELLRECLGAAVPARLRKVASALVPGRRALPVPVYM
LVPAPARGDNSCADSADGTPVTFSSATSLSDETLQGPPRDPPSGRSDRQKPAGREAPARQ
ATGHRHRAWGAGRSPEQARGVGRSREGLELPLRQPSSACKDQDVFRPSPGRGDGALQSLC
LTTPTEEAVYCFYDNDSDEEPSEAVVPPRRASAIPRAVKRERPAGRKEVQAAPKATPKAT
QAARAQPSLIADETPPCYSLSSSASSLSEPDPPEHPAGQPQALKPAANKGLGTAGGRHGP
PSPRVQTGLLRRGANSAVPRRRFQASGSRRRKPQAAQPDKQPAEGPRECGDEAASSDHAS
DLDSVEWRAIQEGANSIVTWLHQAAAAATHEASSGSDSILSGSGLSGSSTLQPSLHRKGR
GLQAGGPAGSTARPEKRDSALAQHSTSGPEKLRGAQKTTGRVPAVLRGRTVIYVPSPAPR
AQPKGHPGTHVAPRKMGPPSPAQPGAPAKTPSPGQQRSRSLHRPGKSSELAALSPPQRSA
TPPARLAKAPSSGSSPASPASQAPTRRLPTGTQAAGPLPGPGAALVPQTPTRALLSKQHK
TQKSPVRIPFMQRPARRGPPALARAAPEPGPRGRAAAEGSPGARGGRLGLVRVASARSSG
SESSDRSGFRRQLTFIKESPGLLRRRRLELSTPEAARPASQGGSPRRSQPALPAVFLCSS
RCDELRAAPRQAPVPQRAPAARPSPSERPARRPSSESPSRLPVRTPTAPPEAVKRYASLP
HISVARRPDGAAPGAGADAARRSSDGEARLLPRVAAPGTTWRRIRDEDVPHILRSTLPAT
ALPLMGAPSEEGPSGPPQRKTSDAVVQTEDFAATKTNSSTSPSLESRGPPQAAVCGPSTL
TGSDVDGLGPPKAPTSAPFVHEGLGVAAGGFPTSRHGSPSRSARVPPFNYVPSPMAAAAT
DLATEKAPAAAPTSLLE
NT seq 7074 nt   +upstreamnt  +downstreamnt
atggcaccaggccttcttcccgcgctgcgattggccgcggcagctgcatcccgcatcccg
catcctcccccgctcgcggtggtctcgcccagccccaggagcggcggcgccgcctgggca
ggccgggaccgggctttgtccgccccggaaccctctgcctgcgccgccaagaccccggag
acccggaacccacgccccgcggcgcccccgccagcccagcccgagcgagataaagcactc
caggagctgaagatggcgagctccgtggcaccctacgagcagctggtgcggcaggtggag
gccttgaaggccgagaacagtcatctgaggcaggagctgcgagacaattccagccacctg
tccaagctagagacggagacgtccggcatgaaggaggtcctgaagcacttacagggcaag
ctggagcaggaggccggagtgctggtgtccttggggcagacggacgtgctggagcagctg
aaagccctgcagatggacatcaccagcctgtacaacctcaagttccaacccccagcccta
agtcccgagcccgcggcgcggacccccgaagaaagtcccgtccatggctctggaccctct
aaggacagttttggggagctgagcagggctactgtccggctgctggaggagctggaccgg
gaacggtgcttcctgttgaacgagatcgagaaggaggagaaggagaagctctggtactac
tcgcagctgcagggcctgtccaagcgcctggacgagctcccgcacgtggagacggtctcg
atgcagatggacctgatccggcagcagctggagttcgaggcccagcacatccgctcgctg
atggaggagcgcttcggcacgtcggacgagatggtgcagcgcgcgcagatccgcgcttcg
cgcctggagcagatcgatcaggagctgctgtccgcccaggaccgcgtgccgcagaccgag
gcccaggccctgctggcggtgaagtcagtgccggtagaggaggacccggagactgaggtc
cccacgcaccctgacgacggtgtccctcagccgggcaacagcaaggtggaggtggtcttc
tggttgctgtccatgctggcgacacgggaccaggaggacacagcccgcaccctgctggcg
atgtccagctcgccggagagctgcgtggcgatgcgccgctcggggtgtctgccgctgctg
ctgcagatcctgcacggcgccgaggcgggcaacgggagccccggggcgccgggagccaag
gatgcacgcatgcgcgccaacgcggcgctgcacaacatagtcttctcgcaaccggaccag
ggcctggcgcgcaaggagatgcgcgtcctgcatgtgttggagcagatccgggcctactgc
gagacctgctgggactggcttcggggcagggacgacgcggacggaggcggcgagggcggc
ggtgagcgcgcaggagctccggtgtggggggcccctgtccccattgagcctcagatctgc
caggccacctgtgccgtgatgaagctgtcctttgatgaggagtaccgccgtgccatgaac
gagctgggtgggctgcaggccgtggcagacttgctgcaggttgactacgagatgcacaag
atgacgcgggacccgctcaaccttgcccttcgccgctacgccggcatgaccctcaccaac
ctcacctttggcgacgtcgccaacaaggccacgctgtgtgcccgccggggctgcatggag
gccatcgtggcccagctggcttctgagagcgaggagctccaccaggtggtgtccagcatc
ctgcgcaacctgtcctggcgggctgacatcaacagcaagaaggtgctgagggaggtcggc
agcatgactgccctgatgcagtgtgttcttcgagcctccaaggagtccaccctgaagagc
gtgctcagtgccctgtggaacctgtcggcacacagcacggagaacaaggcggccatctgc
caggtggacggtgccctgggcttcctggtgagcacactgacccacaagtgccagagcaac
tccctggctatcatcgagagtggcggtggcatcctgcgcaacgtgtccagcctcatcgcc
acccgggaggactacaggcaggtgctgcgggaccacaactgcctgcagacgctgctgcag
cacctgacgtcgcacagcctgaccatcgtgagcaacgcctgcggcacgctctggaacctg
tccgcccgcagcccgcgggaccaagagctcctgtgggacctgggggccgtgggcatgctg
cgcaacctggtgcactccaagcacaagatgatcgccatgggcagcgccgccgccctgcgc
aacctgctggcccaccgccccgccaagtaccagaccaccgccacggccgtctcccccggc
gcatgcgctcccagcctgtacgtgcggaagcagcgggcgctggaggccgagctggacacg
cggcacctggcgcaggcgctcgaccacctggagaagcagggcctgccggaggcggaggcc
gacgcagcctccaagaagcccctgccgcccctgcggcacctggacgggctggcccgggac
tacgcctcggactcgggctgcttcgacgacgatgaggcgccctccctggccgctgtagct
gccactgcggaacctgccagccccgcggtgctgtcgcttttcctggggagccccttcctg
caggggcaggcgctggcccgggccccgccagcccgccgcagtggcccagaggcagagaag
gaggccagcggggaggtggccgtggcggccagggccaaggccaagctggcgctggcggtg
gcacgcatcgacaggctggtggaggacatctctgccctgcacacctcatcagacgacagc
ttcagcctcagctctggggaccctggacaggaagcaccgcgtgaaggccgggcccagtcc
tgctctccttgccggcggccggagggcaggcggccagaggctggcagtcgtgcccacccg
ctgctgcggctcaaggctgcccacgccagtctctccaatgacagtctcaacagcggcagc
accggtgatgggcgctgtccccgcgagcacacacggtcctgcccactggccgtgctggcc
gagcaccgcgaggggtccccgagcagccaggtgcggcccagccggctagacctccacctg
ccaggcagccaggagccggcatcccgggacggctctgccgccgatgcctgtgtacgcacc
atcaagctctcgcccacctaccagcacgtaccgctcttcgagggcaaccccagggcaggc
atggggtccctggcccccggagcccggaagcaggcctggttgcccatggacggcctgagc
aaggtgccggagaagctggtggcagagaccgtgccactgtgcctgtcgcgctgcagctcc
ctgtcctcgctgtcctcggctggccgcccaggccccagtgaggctggggacctggacagt
gactcatccctggaagggctggaggaggctggacccagcaaggctgacctggacggggcc
tggctcggccccggggctgcctccctgcccgtggccatcccggctccgcagcggggccgg
ggcctgggagtggaggacaccaccccgtccagctcctcggagaactgcgtgcaggagacg
ccactggtgctcagccgctgcagttcggtgagctccctgagcagcttcgagagcccgtcc
atcgccagctccgtgcccagtgacccgtgcagcgggttgggcagcggcacggtcagcccc
agcgagctgcccgacagccccgggcagaccatgcctcccagccgcagcaagacgcccccg
ctggcccccgcgccccccggcgagcgggagagcacccagttcagcctgcagtgggagagc
tatgtgaagcgcttcctggacatcgccgaccgccgcgagcgctgccggcttccgtctgag
ctggacgcgggcagcgtgcgcttcaccgtggagaagccggacgagaacttctcctgcgcc
tccagcctcagcgcgctggccctgcacgaacactatgtgcagaaggacgtggagctgcgg
ctgctgcccccagcctgccccgagggtgggggggggggcggggggggcggccccggcctg
cactttgcagggcaccgccggcgggacgaggctggtggctgtctcgagggcccggcagcc
actgaccaggagctggagctgctgcgcgagtgcctgggggcggcggtccccgcccggctc
cgcaaggtggcctcggcgctggtgcctggtcgccgcgcactgcccgtgcccgtctacatg
ctggtgccggcccccgcccgaggggacaactcctgcgctgactccgctgacggcacgccc
gtcaccttctctagtgccacctcgctcagtgacgagacactacagggacctcccagggac
ccgcccagcggacgctccgacaggcagaagcctgcgggtcgtgaggccccggccaggcag
gccacggggcacaggcacagggcatggggtgcaggccggagcccggagcaggcccgcggc
gtgggcaggagcagggaggggctggagcttcccctccgccagccctcgagcgcctgcaag
gaccaggatgtcttccgccccagcccaggccgcggggacggggcgctgcagtctctgtgc
ctcacgacgcccaccgaggaagctgtgtactgcttctacgacaacgactcagacgaggag
ccctccgaggcggtggtgcccccgcggcgggcatccgccattccccgggcagtaaagaga
gagcgcccggctggcaggaaggaggtgcaggctgcacccaaggctacgcccaaggccacg
caagctgcccgtgcccagcccagcctcattgccgatgagacaccgccgtgctactcccta
agctcctccgccagctccctgagtgagcccgatccccccgagcacccagcaggccagccc
caggctctcaagccggctgccaacaaggggctgggcactgcagggggtcgtcatggcccc
ccgagcccgcgggtgcagacagggctgctccggcgcggtgccaactctgcagtgcccagg
cgccggttccaagcgtcgggctctcggcgccgcaagccccaagctgcccagccagacaag
cagcctgcagaggggccccgggagtgcggggacgaggcagccagctctgaccatgcctca
gaccttgacagcgttgagtggcgcgcgatccaggagggcgccaactccatcgtcacgtgg
ctgcaccaggcggcggcggcggccacccacgaggcctcgtctgggtctgactcgatcctg
tccgggtcggggctgtcggggagctccaccctgcaaccctcactgcacaggaagggacgg
gggctgcaggcggggggccccgcgggcagcactgcgaggccggagaaacgggactcggcc
ctggcccagcacagcaccagcggccccgagaagctgcgaggggctcagaagaccacgggc
agggtgccggccgtgctccggggaaggactgtgatctatgtgcccagcccggccccccgg
gcccaacccaaaggccaccctggcacccatgtggcaccgaggaagatgggacccccgagt
cctgcgcagccaggagcccccgccaagacccccagccctgggcagcagcggtctcgaagc
ctgcaccggcctggcaagagctcggagctggcggcactgagccctccccagaggagtgcc
acaccgcccgcccgcctggccaaggccccctcctcggggtcctcccccgcctctccggcc
tcccaggcccctaccaggaggctccccacaggcacccaggcagcagggcccctccccggc
cccggggcagctctggtgccccaaacacccacgcgggccctgctctctaagcagcacaag
acgcagaagtcacctgtgcggatccccttcatgcagaggccagccaggcgggggccgcca
gccctggccagggcagccccggagccgggtccccggggtcgggcggcagcggagggaagc
cctggcgcccgagggggccgcctgggccttgttcgcgtggcctctgcccgctccagtggc
agcgagtcgtcggaccgctcaggtttccggcggcagctgacctttatcaaggagtccccc
ggcctgctgcgccgccgccgtttggaactgtccaccccagaggctgcgcgccccgcctcg
cagggtggctcaccccgccgcagtcaacccgcgctgcccgctgtcttcctctgctcctcg
cgctgcgacgagctgcgggcagcccccaggcaggctccagtcccccagcgagccccggca
gccaggcccagtcccagcgagcggcctgcccggcgccccagctccgagagcccgtcccgc
ctgcctgtgcgcacccccaccgccccacccgaggcggtcaagcggtacgcctccctgccg
cacatcagcgtggcccgcaggcccgacggggccgcccccggggccggtgcggacgctgcc
cgccgcagcagcgatggagaggcccggctgctgccgagggtggcggcaccaggcaccacg
tggcgtcgcatccgggacgaggacgtcccacacatcctgcggagcacgctgcctgccact
gccctgccactgatgggcgccccgtctgaggagggccccagcggccccccacagcgcaag
accagcgacgccgtggtccagacggaggactttgctgccaccaagaccaactccagcacg
tctccgagtctggaaagcagggggcccccccaggctgcagtctgcggccccagcacactc
accggcagtgatgtggacgggcttggcccccccaaagcgcccacctctgctccctttgtc
cacgagggcctgggggtggctgcagggggctttcccaccagccggcatggctcccccagc
cgctcggcccgtgtcccccccttcaactatgtgcccagccccatggcggcagccgccact
gacttggccacagagaaagcccccgccgctgcccctaccagcctcctggaatag

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