KEGG   Mustela putorius furo (domestic ferret): 101679776
Entry
101679776         CDS       T07239                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf01521  EGFR tyrosine kinase inhibitor resistance
mpuf01522  Endocrine resistance
mpuf01524  Platinum drug resistance
mpuf04010  MAPK signaling pathway
mpuf04012  ErbB signaling pathway
mpuf04014  Ras signaling pathway
mpuf04015  Rap1 signaling pathway
mpuf04022  cGMP-PKG signaling pathway
mpuf04024  cAMP signaling pathway
mpuf04062  Chemokine signaling pathway
mpuf04066  HIF-1 signaling pathway
mpuf04068  FoxO signaling pathway
mpuf04071  Sphingolipid signaling pathway
mpuf04072  Phospholipase D signaling pathway
mpuf04140  Autophagy - animal
mpuf04150  mTOR signaling pathway
mpuf04151  PI3K-Akt signaling pathway
mpuf04152  AMPK signaling pathway
mpuf04210  Apoptosis
mpuf04211  Longevity regulating pathway
mpuf04213  Longevity regulating pathway - multiple species
mpuf04218  Cellular senescence
mpuf04261  Adrenergic signaling in cardiomyocytes
mpuf04370  VEGF signaling pathway
mpuf04371  Apelin signaling pathway
mpuf04380  Osteoclast differentiation
mpuf04510  Focal adhesion
mpuf04550  Signaling pathways regulating pluripotency of stem cells
mpuf04611  Platelet activation
mpuf04613  Neutrophil extracellular trap formation
mpuf04620  Toll-like receptor signaling pathway
mpuf04625  C-type lectin receptor signaling pathway
mpuf04630  JAK-STAT signaling pathway
mpuf04660  T cell receptor signaling pathway
mpuf04662  B cell receptor signaling pathway
mpuf04664  Fc epsilon RI signaling pathway
mpuf04666  Fc gamma R-mediated phagocytosis
mpuf04668  TNF signaling pathway
mpuf04722  Neurotrophin signaling pathway
mpuf04725  Cholinergic synapse
mpuf04728  Dopaminergic synapse
mpuf04810  Regulation of actin cytoskeleton
mpuf04910  Insulin signaling pathway
mpuf04914  Progesterone-mediated oocyte maturation
mpuf04915  Estrogen signaling pathway
mpuf04917  Prolactin signaling pathway
mpuf04919  Thyroid hormone signaling pathway
mpuf04920  Adipocytokine signaling pathway
mpuf04922  Glucagon signaling pathway
mpuf04923  Regulation of lipolysis in adipocytes
mpuf04926  Relaxin signaling pathway
mpuf04929  GnRH secretion
mpuf04931  Insulin resistance
mpuf04932  Non-alcoholic fatty liver disease
mpuf04933  AGE-RAGE signaling pathway in diabetic complications
mpuf04935  Growth hormone synthesis, secretion and action
mpuf04936  Alcoholic liver disease
mpuf04973  Carbohydrate digestion and absorption
mpuf05010  Alzheimer disease
mpuf05017  Spinocerebellar ataxia
mpuf05132  Salmonella infection
mpuf05135  Yersinia infection
mpuf05142  Chagas disease
mpuf05145  Toxoplasmosis
mpuf05152  Tuberculosis
mpuf05160  Hepatitis C
mpuf05161  Hepatitis B
mpuf05162  Measles
mpuf05163  Human cytomegalovirus infection
mpuf05164  Influenza A
mpuf05165  Human papillomavirus infection
mpuf05166  Human T-cell leukemia virus 1 infection
mpuf05167  Kaposi sarcoma-associated herpesvirus infection
mpuf05168  Herpes simplex virus 1 infection
mpuf05169  Epstein-Barr virus infection
mpuf05170  Human immunodeficiency virus 1 infection
mpuf05200  Pathways in cancer
mpuf05205  Proteoglycans in cancer
mpuf05207  Chemical carcinogenesis - receptor activation
mpuf05208  Chemical carcinogenesis - reactive oxygen species
mpuf05210  Colorectal cancer
mpuf05211  Renal cell carcinoma
mpuf05212  Pancreatic cancer
mpuf05213  Endometrial cancer
mpuf05214  Glioma
mpuf05215  Prostate cancer
mpuf05218  Melanoma
mpuf05220  Chronic myeloid leukemia
mpuf05221  Acute myeloid leukemia
mpuf05222  Small cell lung cancer
mpuf05223  Non-small cell lung cancer
mpuf05224  Breast cancer
mpuf05225  Hepatocellular carcinoma
mpuf05226  Gastric cancer
mpuf05230  Central carbon metabolism in cancer
mpuf05231  Choline metabolism in cancer
mpuf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mpuf05415  Diabetic cardiomyopathy
mpuf05417  Lipid and atherosclerosis
mpuf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101679776 (AKT3)
   04012 ErbB signaling pathway
    101679776 (AKT3)
   04014 Ras signaling pathway
    101679776 (AKT3)
   04015 Rap1 signaling pathway
    101679776 (AKT3)
   04370 VEGF signaling pathway
    101679776 (AKT3)
   04371 Apelin signaling pathway
    101679776 (AKT3)
   04630 JAK-STAT signaling pathway
    101679776 (AKT3)
   04668 TNF signaling pathway
    101679776 (AKT3)
   04066 HIF-1 signaling pathway
    101679776 (AKT3)
   04068 FoxO signaling pathway
    101679776 (AKT3)
   04072 Phospholipase D signaling pathway
    101679776 (AKT3)
   04071 Sphingolipid signaling pathway
    101679776 (AKT3)
   04024 cAMP signaling pathway
    101679776 (AKT3)
   04022 cGMP-PKG signaling pathway
    101679776 (AKT3)
   04151 PI3K-Akt signaling pathway
    101679776 (AKT3)
   04152 AMPK signaling pathway
    101679776 (AKT3)
   04150 mTOR signaling pathway
    101679776 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101679776 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    101679776 (AKT3)
   04218 Cellular senescence
    101679776 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101679776 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    101679776 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101679776 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101679776 (AKT3)
   04613 Neutrophil extracellular trap formation
    101679776 (AKT3)
   04620 Toll-like receptor signaling pathway
    101679776 (AKT3)
   04625 C-type lectin receptor signaling pathway
    101679776 (AKT3)
   04660 T cell receptor signaling pathway
    101679776 (AKT3)
   04662 B cell receptor signaling pathway
    101679776 (AKT3)
   04664 Fc epsilon RI signaling pathway
    101679776 (AKT3)
   04666 Fc gamma R-mediated phagocytosis
    101679776 (AKT3)
   04062 Chemokine signaling pathway
    101679776 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101679776 (AKT3)
   04922 Glucagon signaling pathway
    101679776 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    101679776 (AKT3)
   04920 Adipocytokine signaling pathway
    101679776 (AKT3)
   04929 GnRH secretion
    101679776 (AKT3)
   04915 Estrogen signaling pathway
    101679776 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    101679776 (AKT3)
   04917 Prolactin signaling pathway
    101679776 (AKT3)
   04926 Relaxin signaling pathway
    101679776 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    101679776 (AKT3)
   04919 Thyroid hormone signaling pathway
    101679776 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101679776 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    101679776 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    101679776 (AKT3)
   04728 Dopaminergic synapse
    101679776 (AKT3)
   04722 Neurotrophin signaling pathway
    101679776 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101679776 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    101679776 (AKT3)
   04213 Longevity regulating pathway - multiple species
    101679776 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101679776 (AKT3)
   05205 Proteoglycans in cancer
    101679776 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    101679776 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    101679776 (AKT3)
   05230 Central carbon metabolism in cancer
    101679776 (AKT3)
   05231 Choline metabolism in cancer
    101679776 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101679776 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101679776 (AKT3)
   05212 Pancreatic cancer
    101679776 (AKT3)
   05225 Hepatocellular carcinoma
    101679776 (AKT3)
   05226 Gastric cancer
    101679776 (AKT3)
   05214 Glioma
    101679776 (AKT3)
   05221 Acute myeloid leukemia
    101679776 (AKT3)
   05220 Chronic myeloid leukemia
    101679776 (AKT3)
   05218 Melanoma
    101679776 (AKT3)
   05211 Renal cell carcinoma
    101679776 (AKT3)
   05215 Prostate cancer
    101679776 (AKT3)
   05213 Endometrial cancer
    101679776 (AKT3)
   05224 Breast cancer
    101679776 (AKT3)
   05222 Small cell lung cancer
    101679776 (AKT3)
   05223 Non-small cell lung cancer
    101679776 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101679776 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    101679776 (AKT3)
   05161 Hepatitis B
    101679776 (AKT3)
   05160 Hepatitis C
    101679776 (AKT3)
   05164 Influenza A
    101679776 (AKT3)
   05162 Measles
    101679776 (AKT3)
   05168 Herpes simplex virus 1 infection
    101679776 (AKT3)
   05163 Human cytomegalovirus infection
    101679776 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101679776 (AKT3)
   05169 Epstein-Barr virus infection
    101679776 (AKT3)
   05165 Human papillomavirus infection
    101679776 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101679776 (AKT3)
   05135 Yersinia infection
    101679776 (AKT3)
   05152 Tuberculosis
    101679776 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101679776 (AKT3)
   05142 Chagas disease
    101679776 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101679776 (AKT3)
   05017 Spinocerebellar ataxia
    101679776 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101679776 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    101679776 (AKT3)
   05415 Diabetic cardiomyopathy
    101679776 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101679776 (AKT3)
   04932 Non-alcoholic fatty liver disease
    101679776 (AKT3)
   04931 Insulin resistance
    101679776 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101679776 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101679776 (AKT3)
   01524 Platinum drug resistance
    101679776 (AKT3)
   01522 Endocrine resistance
    101679776 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mpuf01001]
    101679776 (AKT3)
Enzymes [BR:mpuf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     101679776 (AKT3)
Protein kinases [BR:mpuf01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   101679776 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1 PH_11
Other DBs
NCBI-GeneID: 101679776
NCBI-ProteinID: XP_004756832
Ensembl: ENSMPUG00000015730
UniProt: A0A8U0SG63
LinkDB
Position
Unknown
AA seq 479 aa
MSDVTVVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCVDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagcgatgttaccgttgtgaaagaaggctgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaacctcaagatgtggatttaccttatcccctcaacaacttttcagtggcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacatttattatcagatgtcttcagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagggaagagtggacagaa
gccattcaggctgtagcagacagacttcagagacaagaagaggagagaatgaattgtagt
ccaacttcacaaattgataatataggggaggaagagatggatgcttccacaacccatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg
aaagttattttggttcgagagaaggcaagtggcaaatactatgctatgaagattctgaag
aaggaagttattattgcaaaggacgaagtggcacacactctaactgagagcagagtatta
aagaacactagacatccctttttaacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgtaaatggtggagagctgtttttccatttgtcgagagag
cgggtgttctccgaggaccgcacacgtttctatggtgcagaaattgtctctgctttggac
tatctacattccggaaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaattacagattttggactttgcaaagaagggatcacagatgca
gccaccatgaagacattctgtggcacaccagagtatctggcaccagaggtgttagaagac
aacgactatggccgagccgtggattggtggggcctgggggttgtcatgtatgagatgatg
tgtgggaggctacctttctacaaccaggatcatgagaaactttttgaactaatactaatg
gaagacattaaatttcctcgaacactctcttcagatgcaaaatcactgctttcagggctt
ttgataaaggatccaaataaacgccttggcgggggcccagatgatgcaaaagaaattatg
aggcacagtttcttctctggagtcaactggcaagatgtatacgataaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagataccagatattttgatgaagaatttaca
gctcagactattacaataacgccacctgaaaaatatgacgaggacggcatggactgcgtc
gacaacgagcggcggccgcatttccctcagttctcctattctgccagcggccgcgagtaa

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