Mustela putorius furo (domestic ferret): 101680315 Help Entry 101680315         CDS       T07239                                  Symbol TOP2A Name (RefSeq) DNA topoisomerase 2-alpha   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism mpuf  Mustela putorius furo (domestic ferret) Pathway mpuf01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:mpuf00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101680315 (TOP2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:mpuf03032]     101680315 (TOP2A)    03036 Chromosome and associated proteins [BR:mpuf03036]     101680315 (TOP2A) Enzymes [BR:mpuf01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      101680315 (TOP2A) DNA replication proteins [BR:mpuf03032]  Eukaryotic type   DNA Topoisomerases    101680315 (TOP2A) Chromosome and associated proteins [BR:mpuf03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     101680315 (TOP2A)   Centrosome formation proteins    Centriole proteins     101680315 (TOP2A) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim Motif Other DBs NCBI-GeneID:  101680315 NCBI-ProteinID:  XP_012918099 Ensembl:  ENSMPUG00000014680 UniProt:  A0A8U0RK53 LinkDB All DBs Position Unknown AA seq 1534 aa AA seqDB search MEVSPLQPVNENMQISKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQH MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TASREYKKMFKQTWMNNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKVIHEQVNPRWEVC LTMSEKGFQQISFVNSIATSKGGRHVDYIADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM WIFVNALIENPTFDSQTKENMTLQVKSFGSTCLLSEKFIKAAIGCGIVESILNWVKFKAQ IQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR GYDSDPVKAWKEAQQKVPDEEENEESDNENEAEKSDSVRDSGPTFNYLLDMPLWYLTKEK KDELCKLRNEKEQELETLKRKSPSDLWREDLAAFIEELEAVETKEKQEEQIGLPGKGGKA KGKKTQMAEVLPSPCGKRVIPRVTVEMKAEAEKKIKKKIKNENTEGNPPEDSIEPEGLKQ RLEKKQKREPGTKTKKQTTLSFKPIKKGKKRNPWSDSESDMSSNESNFDVPPREIEPRRA ATKTKFTVDLDSDDDFSDFDEKTQDEDFVPSSDVSPLKTKASPKHATKELKPQKSATSVM DVDADDAKDSVLLPPGSPAADFSTETEILNPVAKKKVVVKKIAAKSQSSTSTKGAKKGAA PKGTKKDPGLNSDVPQKPDPPKTKTRRKRKPSTSDDSDSNFEKMISKTVTNKKSKAESED FHLDLDSAVAPRAKSGRAKKPIKYLEESDEDDLF NT seq 4605 nt NT seq  +upstreamnt  +downstreamnt atggaggtgtcaccattgcagcctgtaaatgaaaatatgcaaatcagcaaaacaaagaaa aatgaagatgccaagaaaagattgtctattgaaagaatctatcaaaagaaaacccaactg gaacatattttgctccgcccagacacctacattggctctgtggaattagtgacccagcac atgtgggtttacgatgaagatattggcattaactatagggaagtcacctttgtccctggg ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggaccca aaaatgtcttgtattagagtcacaattgacccggaaaataacttaattagtatatggaat aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt ggtcgaaatggctatggagccaaactgtgtaacatattcagtaccaaatttactgtggaa acagccagtagagaatacaagaaaatgttcaaacagacatggatgaataatatggggaga gctggtgagatggaactcaagccctttaatggtgaagattatacatgtattacattccag cctgatttgtccaagtttaaaatgcaaagcctagataaagatattgttgcactgatggtt agaagagcatatgatattgctggatccactaaagatgtcaaagtctttctcaatggaaat aagctgccggtaaaaggatttcgtagctatgtagatatgtatttgaaggataaggtagat gaaactggcaatccattgaaagttatccatgaacaagtaaaccccaggtgggaagtatgt ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc aagggtggcagacatgttgattacatagctgatcagattgtgactaaacttgttgatgtc gtgaagaagaagaacaagggtggtgttgcagtaaaagcgcatcaggtgaaaaatcacatg tggatttttgtgaatgccttaattgagaacccaacctttgactctcagacaaaagaaaac atgactttgcaagtcaagagctttggatcaacatgccttttaagtgaaaaattcatcaaa gctgcaattggctgtggtatagtggaaagcatactaaactgggtgaagtttaaggcccaa atccaattaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa cttgatgatgccaatgatgcagggggtcgaaactccaatgaatgtacactcatcctgact gagggagactcagctaaaactttggctgtttcaggacttggtgtagttgggagagacaaa tacggggttttcccacttagaggaaaaatactcaatgttcgagaagcttctcataaacag atcatggaaaatgctgaaattaacaatatcatcaagattgtgggtcttcaatacaagaaa aactatgaagatgaagattcattgaagactcttcgttatggaaagataatgattatgaca gatcaggaccaagatggttcccatatcaaaggcctgctgattaattttatccatcataac tggccctctcttctacggcatcgttttctggaagaatttatcactcccattgtaaaggtg tctaaaaacaaacaagaaatggcattctatagtcttcctgaatttgaagaatggaagagt tctactccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcaccagcaca tcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtattcagtttaaatat tctggtcctgaagatgatgctgccattagcctggcctttagcaagaaacagatagatgat cggaaagaatggttaacccatttcatggaggatagaaggcaacggaagttacttggcctt cctgaggattacttgtatggacaaactaccacatatctgacatacaatgacttcataaat aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat ggcttgaaaccaggtcaaagaaaggttttgtttacctgtttcaaacggaatgacaagcga gaggtgaaggttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggt gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat ctgaacctcttgcagcccattggtcaatttggtactaggctgcatggtggcaaggattct gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca aaagatgatcacacattgaagtttttatatgatgacaatcagcgtgttgaacctgagtgg tatattcctattatacccatggtgctgataaatggtgctgaaggaattggtactgggtgg tcctgcaaaatccccaactttgatattcgtgaagttgtaaataatatcaggcgtttgatg gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactatcgaa gaactggctccaaatcagtacgtgatcagtggtgaagtggctattcttaattccacaacc attgaaatctcagagcttccgatcagaacatggacccagacatataaagaacaggttcta gaacccatgttgaatggaactgagaagactccacctctcataacagactatagggaatac catacagacactacagtgaagtttgttgtgaaaatgactgaagagaaactggcagaggca gagagagtgggactacacaaagttttcaaactccaaactagtctcacatgcaactctatg gtgctttttgaccatgtaggatgtttaaagaaatatgacacggtgttggatattctaaga gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg ggatacgattcagatcccgtgaaggcttggaaagaggcacagcaaaaggtaccagatgaa gaagagaatgaagagagtgacaatgaaaatgaagctgaaaagagtgactctgtaagagat tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcactaaggagaag aaggatgaactgtgtaagctgagaaatgaaaaagagcaagagctagaaacattaaagaga aagagtccatcagatttgtggagagaagacttggctgcttttattgaagagctggaggct gttgaaacaaaggaaaaacaagaagaacaaataggacttcctgggaaaggggggaaagca aaggggaaaaaaacacaaatggctgaagttctgccttctccatgtgggaaaagagtcatc ccccgagtgaccgtagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag aatgaaaacactgaagggaaccctccagaagacagtattgaaccagaaggtctgaaacaa aggttggagaaaaaacagaaaagagaaccaggtaccaagacaaagaagcaaactacattg tcatttaaaccaatcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat atgagcagtaatgaaagtaactttgatgtccctccacgagagatagagccacggagagca gcaacaaaaaccaaattcacagtggatttggattcagatgacgatttctcggattttgat gaaaaaactcaagatgaagattttgtcccatcatcagatgttagtccacttaagaccaaa gcttccccaaaacatgctaccaaagaactgaaaccacagaaaagtgccacatcagtaatg gacgttgatgctgatgatgccaaggacagtgtactacttcctccaggttctcctgctgct gatttctcaactgaaactgaaatcctaaaccctgttgctaaaaagaaggtggtggtgaag aagatagctgcaaaaagtcagtcttccacctccactaaaggtgccaagaaaggggctgca ccaaaaggaactaaaaaggatccaggcttgaattccgatgtacctcaaaagcctgatccc cccaaaaccaaaactcgccgcaaaaggaaaccatccacttctgatgattctgactctaat tttgagaaaatgatttctaaaacagtcacaaacaagaaatccaaggcggagagtgaggac ttccatctggacttagactcagctgtggctcctcgggccaaatcaggacgggcaaagaaa cctataaagtacctcgaagaatcagatgaagatgatctgttctaa

DBGET integrated database retrieval system