Mustela putorius furo (domestic ferret): 101680482
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Entry
101680482 CDS
T07239
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X2
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
mpuf
Mustela putorius furo (domestic ferret)
Pathway
mpuf05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
mpuf00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
101680482 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
mpuf03021
]
101680482 (SETX)
Enzymes [BR:
mpuf01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
101680482 (SETX)
5.6.2.5 RNA 5'-3' helicase
101680482 (SETX)
Transcription machinery [BR:
mpuf03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
101680482 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
nSTAND3
AAA_22
ResIII
SLFN-g3_helicase
Helicase_RecD
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
101680482
NCBI-ProteinID:
XP_004757124
Ensembl:
ENSMPUG00000012542
UniProt:
M3YM90
LinkDB
All DBs
Position
Unknown
AA seq
2682 aa
AA seq
DB search
MSTCCWCTPGGTSTVGFLKRYASRTHSGEFQTADEDLCYCLECVAEYHRARDDLPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSILEKGKLILLPSHMYDTSNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNVSYNKEIQNIRNSSVRTKLEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHRHKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIKNIKVKVP
QYNTFVDLSPACKSSPASYSKEENEQIDRKSNKDLSCLESSSPTFPKEPMKAETYKMQEN
VLIKANNTVEEDNEQNFIKDWKLEDHVPAESCIKKSSKNLFTEKGQDHVKKSTGKQKSVK
ENCTSRNDPERGCDRGIIMSTRLLTSSSTESLEKASTSTEDFSFKDDALGKTSKSKTKAR
KDEICAKLSHVIKKQHRKGTLVSNTGNLEENLAVSNIDSFYSRKDSGGQKGDGFMHNLSL
DPNGLLDDKNGEQKSQNSLLLKKKPLKSEELDIFSSHENSYQIQECHIDNKDLVSFTEVT
NTFVKKTSPFKDPVTVLESRDKESSKNTSQLSSHLREQALGLSPQSDTLTDSQVDRDLHK
LSLIAQASVIKFPSDSTQKSSSQLQRRVKDGRRRFLADQNNTGEACRGQIIIISDSDDDD
DDDEILGFERHIKQDKIGIKKECPEQHTSVANANVEKKLIKEEETKSLLQFEESDSQIFE
FESPGEVFSVWQDQEPDKNSVQENEKNSCSADIADITNDWGYETDYVSEEVIKKVAEGIE
KHTEPQSSISVGEIRETEVKKRKRKRFEKPMAEDHPRPSPSDRNEDQPDILNERSVTEND
FKSVDLRTSPSSSVQRDKDTTVALKKSSPKLRSYSKPIRRVPLSKTPKKTHSDTKKGQSK
SSNYISCRTTPAIVPPKKLRQCPEPTSTVEKLGLKKAPRRAFELSQRSLEYLVQLRDHGK
TVGVVDTRKKTKLISPQTLSVKNNKKLLTSQDLQLRRQMRSKSQKNRQGLSDYESKDTTR
AGPCAAQNSDILVPESDGSDYRSKGGTEVVANTTGKQSIKRASKEPEPMKTKYVSQVTDD
TCLLSPCASVVLNGRIPTNEINVSASANPLGGSDPIVHRLELATLKDGELDSNSDTEDEN
IFLTQHNPEDMDLCSQVENGNEKLIEVIRGKDKAQVEEDSVSRPQLESWSSTKCKYKDCV
ETPKNQGEYCAKHSEAKAADEDVFRKPGLPLSASKPSRPSTAKIFSSSSTSRIANLSKSL
ESTPALPPALKNKSSGAQAVSKVPQPASVLSPKPAGEVKSLCNVLHPQTPNNSNRQGYKL
TFGESKSFSASTPVNILLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPASLCQSISRPVP
IRFQDCGDYFNVFFPLMILNTFETVAQEWISSPNKEKFYQLHLRKFPADYKKYWEFVVHL
EECELAKQLHPKENDLVFLIPERQNGENKDTERDHMEDLRDYHCAYVHKFRRTSVMRNGK
SECSLSIQTQDNLPVNLNELVKCIVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDF
CTKDLLTTTSERIITYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIV
GLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNP
LGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQEMHRRKEFLDRQLDEL
SRQRALCRGGREMQRQELDEEIAKVSKERQELASKIKEVQGRPQKTQSIIILESHVICCT
LSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPT
VISMKAQEYGYDQSMMARFYKLLEDSVEHSVVGRLPVLQLTVQYRMHPDICLFPSSYVYN
RSLKTSRQTETSRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEIIKLIKDKR
RDVTFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDGFQGRQKDCVIVTCVRANT
VQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTCDRN
YRHDAAKILKLKPVLQRSATHPPAVAPEASRPLGGLPSSRLDSELAKTSITSLYHTPSDS
RESAGPVTAKDPERPLIQDRLRDPRLLRRLGLDPETRGPCLRDPQPSSPQHPGATPPSGE
PGFPGSPQDVGGAQQSTARGAALNNHKPQAHCDPAAAGTEDSASKRRCDWEEGLGSRRET
RAFSEGDQETWSPESYRSKRNPGWDRRGLEREDGSSKRRRLS
NT seq
8049 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgcacgcccggtggcacttccaccgttggcttcctgaagcgc
tacgcgtccaggacccactccggcgagtttcaaacagctgacgaagacctctgctattgc
ttagagtgtgtggccgaataccacagagcaagggacgatttaccattcctgcatgaggtt
ttatgggaattagaaacgttacgtctcataaatcactttgaaaaatccatgaaggcagaa
attggagatgatgatgaattgtatatagtagacaacaatggagaggcacagctgtttgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatctgcttttacatgagcgtgttaatgaattatgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccgggcatctatttgtttttg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaatttgggaaaa
gtggacagagatgattattatgacttgcaggaggttttgacttgtctttttaaagtcatc
gagttggggcttttggaaagtccagacatttatacttcttctatcctcgagaagggtaaa
ctgattcttctgccctcacacatgtatgataccagcaactacaaaaactattggttaggt
atttgtatgttgctgaccattctggaggagcaggccatggactcactgttgctaggctca
gacaaacagaatgatttcatgcagtcaatacttcacaccatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcattacactgtttcatggtgattctggatcgcctc
ggatccaaggtttggggtcaacgtatcgatcctattgaggcatttcaaaccattatcaac
aatgtgagctacaataaagagatccagaatatacggaacagctctgtgaggaccaagtta
gaaccggagtcatatttggatgatatggtgacttgcagccagattgtatacaattataat
cccgagaagaccaaaaaggattcggggtggagatcagccatttgcccggattattgtcct
aacatgtatgaagagatggaaacattagccagtgtgcttcagtcagatattggtcaagac
atgcgtgttcataacagcacgtttctgtggttcatcccttttgttcagtccctcatggat
cttaaggatttgggtgtggcttatatagtggaggttattcatcatctgcactccgaagtc
aaagatgtcctcaaccaaacagatgctgtttgtgacaaagttactgaattttttctccta
attttggtgtccgtgattgagctgcatagacataaaaaatgtctgcatctgctgtgggtt
agttcccagcaatgggtagaagctgttgtaaaatgtgccaagcttcctaccactgcattt
gcacggagttccgagaagtcatctggaaattgctccaaaggaacagcaatgatatcatct
ctgtcattgcattcaatgccatcgaattctgtgcagctggcttgtgtgcagctgattaga
agtctccttaaagaaggttatcagcttgggcagcaaactctatgtaagcgattctgggat
aagctcaacttatttctgcgtggaaatttatcgctaggttggcagttgactactcaggaa
acccatgaattacaaacttgtttaaagcaaattattaaaaacataaaagtcaaagtacct
caatataacacttttgtggatctgagtcctgcatgtaaaagctctcctgcatcttacagt
aaagaagaaaatgaacaaatagataggaagtctaataaagacctgtcctgtctagaaagc
tccagcccaacatttcctaaagaaccaatgaaagcggagacctataagatgcaagagaat
gtgttgatcaaagcaaataacactgtagaagaggataatgagcaaaattttataaaagac
tggaaactagaagatcatgtcccagccgagtcatgcataaagaagagtagtaaaaacctt
ttcactgaaaaaggtcaagatcacgttaaaaaaagtacagggaagcagaagtctgtgaaa
gagaattgtacttcaaggaatgatccagaaaggggatgtgacagaggaataatcatgtca
acacgtttgttaaccagctctagcactgaatctctggagaaggcatccacatcaactgag
gatttctctttcaaagatgatgctcttggcaaaacctcaaaatcaaaaactaaggcacgt
aaagatgaaatctgtgctaagttatcacatgtaataaagaagcaacacaggaaaggaact
ttggtcagtaatactggtaatttagaggaaaacctagctgtgtctaacattgacagtttc
tattcaaggaaagattcaggaggtcagaaaggggacggctttatgcacaatctctcttta
gatcctaatggccttctggatgataaaaatggggaacaaaaatctcaaaacagcttattg
ctgaaaaagaaaccactgaagagtgaagaattagatattttctcgtcccatgaaaacagc
tatcaaatacaggaatgtcacattgataataaagatttggtctcatttacagaagtgacc
aacacttttgtgaagaaaacttctcccttcaaagatcctgtgactgttcttgaatcaaga
gataaggaaagtagcaagaacactagtcagttgtcttctcacttgagagaacaagctctt
ggcctaagtcctcagtctgacaccttaacagattctcaggtagacagagacctccacaag
ttatctttaatagctcaggccagtgttattaagttcccatcagattcaactcaaaaaagc
tcatcccagttacaaagaagagtgaaagatggcagaaggcgtttcctggctgaccagaat
aatactggggaagcctgccgcggccagattattattatttcagattctgatgatgatgac
gatgatgatgaaatcctgggttttgagagacatattaagcaagataaaataggcatcaag
aaagaatgtccggagcagcatacttcagtagctaatgcgaatgtggaaaagaagctaata
aaggaagaggagacaaagtcccttttgcagtttgaggaatcggattctcagatttttgag
tttgaaagtccaggtgaagtgttttctgtttggcaagatcaggaaccagacaagaattca
gttcaagagaatgagaaaaattcttgttcagctgacatagctgatatcacaaatgattgg
ggttatgaaacagattatgtatctgaagaggttattaagaaagtagcagaaggcattgaa
aaacacacagaaccgcagagcagtatttctgttggggaaattcgtgaaactgaagtaaaa
aaacgtaagcgaaaacgatttgaaaaacctatggctgaagatcatccaagaccttcacct
tctgatagaaatgaggaccagcctgatattcttaatgagagaagtgtgactgaaaatgat
tttaaaagtgtggacctaaggacaagtcccagttcaagtgttcagagagacaaagacact
acagttgcactaaagaagtcttctccaaagcttcgttcttattccaaacccattaggaga
gtcccactttctaaaactcctaagaaaacgcattcagataccaagaaagggcagagtaaa
agttcaaattacatcagttgtaggaccactcctgctatagttccaccaaagaagttgcgc
cagtgccctgagccaacttcaacagttgagaaacttggtctaaagaaggctcctcgtagg
gcatttgagttgtctcagcgatctctagagtatttagttcagttacgcgaccatggcaaa
actgttggagtggttgatactagaaaaaagactaagttaatttcccctcagactctctct
gtgaaaaataataagaaactgctgacaagtcaagatcttcagttgcgaaggcagatgaga
tccaaatcacaaaaaaatagacaaggactttcagattatgaaagtaaagatactacaaga
gcaggaccgtgtgcagcacagaattctgacatacttgtcccagaatcagatggttcagat
tatcgttctaaaggaggaactgaggtggttgctaacaccactgggaaacagtcaataaaa
cgtgcatctaaagaaccagaacccatgaaaacaaaatacgtctctcaagtgacagatgat
acttgcctcttgagcccgtgtgcttctgttgtgttaaatggaagaataccaacaaatgaa
ataaatgtctctgcttcagccaaccccttaggtggaagtgacccaatagtacatcgttta
gagttggcaactttgaaagacggagagctggactcgaacagtgatacagaagatgagaat
atatttctgacacagcacaaccctgaagatatggatttgtgttcacaggtggagaacggt
aatgagaaactcattgaagtaattcgtggcaaagataaagcacaggtggaagaagattct
gtaagtcggcctcagttggaatcttggagtagcacaaaatgtaagtacaaagattgtgtt
gaaacaccgaaaaaccagggtgaatactgcgcaaaacactctgaagccaaagcagccgat
gaagatgtatttcgtaaacctggcttgcctctttctgcatctaagccttcgagaccttcc
actgctaagatttttagctcaagtagtacttcacgaattgctaatctttccaagtctttg
gaaagtacccctgcacttccaccagctctaaaaaataagtcaagtggggcacaggctgtt
tcgaaagtcccacagccagcctctgtgttgtctccaaagccggcgggtgaagtgaagagt
ttgtgcaatgttcttcatcctcagactccaaataattccaacaggcaaggttacaaactg
acgtttggtgaaagcaaatccttctcagcttccactccagtcaacattctcttgtcatca
cagtccatctctgacacctttgtcaaagaggtcttaaaatggaaatatgaaatgtttgtg
aactttgatcagtgcgggcccccagcaagcctttgtcagtccatctcaagacctgtgcct
atcagatttcaagattgtggcgattattttaatgtttttttccctttgatgatactgaat
actttcgaaacagtggcacaggagtggatcagctctccaaacaaagaaaaattctatcag
ttgcatttacgaaaatttcctgctgattataaaaaatactgggagtttgtggttcatctt
gaggaatgtgaactcgctaaacaacttcatccaaaggaaaatgatttggtgtttttgatt
cccgaaagacaaaacggagagaataaagatacagagagagatcacatggaagatctccgt
gattaccactgcgcgtatgttcataagtttcgccgcacttctgtcatgcgcaacgggaag
tctgagtgttccctttccatccagactcaagataatttgccagtcaatttaaatgagctc
gtgaaatgcattgtgatcagttctctggtaactacacaaaggaagttgaaagccatgtct
ttgttgagtggacggaaccaactggccagagctgttctgaatccaaaccctatggacttc
tgtacgaaagatttactaactacaacatctgagagaattatcacctacttaagagatttc
aacgaagaccagaagaaagcgatagaaactgcatatgccatggtcaagcactccccgtct
gttgccaagatctgtctgatacatggaccgcctggaacaggaaaatcaaaaactattgtt
ggcctcctgtaccgcctcctgacagagaaccagaggaagggccattcagatgaaaactcc
aatgccaaaatcaaacaaaaccgtgtccttgtgtgtgcgccttccaacgcagctgttgat
gagcttatgaaaaaaatcatcctcgaatttaaagaaaaatgtaaagacaagaagaatcct
ttgggaaactgtggagatataaatttagtacgtctcggtccagaaaagtctattaataat
gaggtcctaaaattcagtttggatagccaagttaaccacagaatgaaaaaagacttacct
tctcatgttcaggaaatgcatagaagaaaggaatttctagatcgtcaactagatgaactt
tcccgccagcgtgctttatgccgaggtggaagggaaatgcagaggcaagaattagatgaa
gaaattgcaaaagtttcaaaagagaggcaagaactagcttctaaaattaaagaggttcaa
ggacgcccacaaaaaacacagagcatcatcatcttggagtcccatgtcatctgctgcaca
ctgagcacaagtggtggcttactgctggagtctgcttttcgtgggcaagggggtgtcccc
ttcagttgtgtcattgtggatgaggccgggcagtcttgtgaggttgagactctcactcca
ctcatccatcgttgtaacaagctcatcctcgtgggagatccgaaacagctccctcccacg
gtcatttctatgaaagctcaggagtacggctatgaccagtcaatgatggcgcgcttctac
aagctgctggaagacagcgtggagcacagtgtggtcggccggctgccggtcctgcagctc
accgttcagtaccggatgcacccggacatctgtctcttcccctccagctatgtttacaac
agaagcttgaagacgagcagacagactgaaaccagtcgctgttcatcagactggccattt
caaccttacctggtgttcgatgttggagacggttcagaaagacgggacaatgactcatat
gtaaatgttcaagaaataaaactggtaatggaaataattaaacttattaaagacaaaaga
agggatgttactttccggaacattggcataataacccattacaaggctcagaagacgatg
attcagaaggatttggacaaagaatttgatagaaaagggccagcagaagtagataccgtg
gatgggttccagggccggcagaaggattgtgtcattgtcacgtgtgtccgagcaaatacc
gtgcagggctcaattgggtttctggcaagtttgcagagactgaacgtcaccatcacacga
gccaagtacagcctcttcatccttggacacttaaggaccctcatggagaaccagcactgg
aaccacctgatccaggatgcccagaagcggggcgccatcatcaagacgtgtgacaggaac
tacaggcacgacgcggccaagatcctgaagctgaagccagtgctgcagagaagcgcgaca
cacccccccgccgtcgcccccgaggcgtccagacccctgggcggcttgcccagcagcagg
ctggacagcgagcttgccaagacgtccatcacgtctctctaccacacgccctcggactcc
agggagtctgctggtcccgtcacggcaaaggaccctgaaaggccccttatccaggaccgg
cttcgggacccaagactgcttaggaggctgggcctggaccctgaaaccagagggccgtgc
ctcagggatccgcagccttcaagcccccagcatcccggggcgacaccgccctcgggggag
ccaggcttccccgggagtccccaggatgtgggaggcgctcagcagtccactgccaggggg
gccgctctgaacaaccacaaacctcaggcacactgtgaccctgcagctgctgggaccgag
gactccgcgagtaaaagaagatgtgactgggaagaagggctcggctccaggagagagacg
cgagctttcagtgagggggaccaagagacgtggagcccggagagctaccgctcgaagagg
aacccgggctgggacaggaggggcctggagagggaggacggcagctccaagagaaggaga
ctttcctag
DBGET
integrated database retrieval system
