KEGG   Mustela putorius furo (domestic ferret): 101681349
Entry
101681349         CDS       T07239                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf01522  Endocrine resistance
mpuf04010  MAPK signaling pathway
mpuf04012  ErbB signaling pathway
mpuf04014  Ras signaling pathway
mpuf04024  cAMP signaling pathway
mpuf04068  FoxO signaling pathway
mpuf04071  Sphingolipid signaling pathway
mpuf04137  Mitophagy - animal
mpuf04140  Autophagy - animal
mpuf04141  Protein processing in endoplasmic reticulum
mpuf04210  Apoptosis
mpuf04215  Apoptosis - multiple species
mpuf04217  Necroptosis
mpuf04310  Wnt signaling pathway
mpuf04380  Osteoclast differentiation
mpuf04510  Focal adhesion
mpuf04530  Tight junction
mpuf04620  Toll-like receptor signaling pathway
mpuf04621  NOD-like receptor signaling pathway
mpuf04622  RIG-I-like receptor signaling pathway
mpuf04625  C-type lectin receptor signaling pathway
mpuf04657  IL-17 signaling pathway
mpuf04658  Th1 and Th2 cell differentiation
mpuf04659  Th17 cell differentiation
mpuf04660  T cell receptor signaling pathway
mpuf04664  Fc epsilon RI signaling pathway
mpuf04668  TNF signaling pathway
mpuf04722  Neurotrophin signaling pathway
mpuf04723  Retrograde endocannabinoid signaling
mpuf04728  Dopaminergic synapse
mpuf04750  Inflammatory mediator regulation of TRP channels
mpuf04910  Insulin signaling pathway
mpuf04912  GnRH signaling pathway
mpuf04914  Progesterone-mediated oocyte maturation
mpuf04917  Prolactin signaling pathway
mpuf04920  Adipocytokine signaling pathway
mpuf04926  Relaxin signaling pathway
mpuf04930  Type II diabetes mellitus
mpuf04931  Insulin resistance
mpuf04932  Non-alcoholic fatty liver disease
mpuf04933  AGE-RAGE signaling pathway in diabetic complications
mpuf04935  Growth hormone synthesis, secretion and action
mpuf04936  Alcoholic liver disease
mpuf05010  Alzheimer disease
mpuf05012  Parkinson disease
mpuf05016  Huntington disease
mpuf05017  Spinocerebellar ataxia
mpuf05020  Prion disease
mpuf05022  Pathways of neurodegeneration - multiple diseases
mpuf05132  Salmonella infection
mpuf05133  Pertussis
mpuf05135  Yersinia infection
mpuf05142  Chagas disease
mpuf05145  Toxoplasmosis
mpuf05152  Tuberculosis
mpuf05161  Hepatitis B
mpuf05162  Measles
mpuf05166  Human T-cell leukemia virus 1 infection
mpuf05167  Kaposi sarcoma-associated herpesvirus infection
mpuf05169  Epstein-Barr virus infection
mpuf05170  Human immunodeficiency virus 1 infection
mpuf05171  Coronavirus disease - COVID-19
mpuf05200  Pathways in cancer
mpuf05208  Chemical carcinogenesis - reactive oxygen species
mpuf05210  Colorectal cancer
mpuf05212  Pancreatic cancer
mpuf05231  Choline metabolism in cancer
mpuf05415  Diabetic cardiomyopathy
mpuf05417  Lipid and atherosclerosis
mpuf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101681349 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101681349 (MAPK10)
   04012 ErbB signaling pathway
    101681349 (MAPK10)
   04014 Ras signaling pathway
    101681349 (MAPK10)
   04310 Wnt signaling pathway
    101681349 (MAPK10)
   04668 TNF signaling pathway
    101681349 (MAPK10)
   04068 FoxO signaling pathway
    101681349 (MAPK10)
   04071 Sphingolipid signaling pathway
    101681349 (MAPK10)
   04024 cAMP signaling pathway
    101681349 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101681349 (MAPK10)
   04137 Mitophagy - animal
    101681349 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    101681349 (MAPK10)
   04215 Apoptosis - multiple species
    101681349 (MAPK10)
   04217 Necroptosis
    101681349 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101681349 (MAPK10)
   04530 Tight junction
    101681349 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101681349 (MAPK10)
   04621 NOD-like receptor signaling pathway
    101681349 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    101681349 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    101681349 (MAPK10)
   04660 T cell receptor signaling pathway
    101681349 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    101681349 (MAPK10)
   04659 Th17 cell differentiation
    101681349 (MAPK10)
   04657 IL-17 signaling pathway
    101681349 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    101681349 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101681349 (MAPK10)
   04920 Adipocytokine signaling pathway
    101681349 (MAPK10)
   04912 GnRH signaling pathway
    101681349 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    101681349 (MAPK10)
   04917 Prolactin signaling pathway
    101681349 (MAPK10)
   04926 Relaxin signaling pathway
    101681349 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    101681349 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    101681349 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    101681349 (MAPK10)
   04722 Neurotrophin signaling pathway
    101681349 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101681349 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101681349 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101681349 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    101681349 (MAPK10)
   05231 Choline metabolism in cancer
    101681349 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101681349 (MAPK10)
   05212 Pancreatic cancer
    101681349 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101681349 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    101681349 (MAPK10)
   05161 Hepatitis B
    101681349 (MAPK10)
   05171 Coronavirus disease - COVID-19
    101681349 (MAPK10)
   05162 Measles
    101681349 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101681349 (MAPK10)
   05169 Epstein-Barr virus infection
    101681349 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101681349 (MAPK10)
   05135 Yersinia infection
    101681349 (MAPK10)
   05133 Pertussis
    101681349 (MAPK10)
   05152 Tuberculosis
    101681349 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101681349 (MAPK10)
   05142 Chagas disease
    101681349 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101681349 (MAPK10)
   05012 Parkinson disease
    101681349 (MAPK10)
   05016 Huntington disease
    101681349 (MAPK10)
   05017 Spinocerebellar ataxia
    101681349 (MAPK10)
   05020 Prion disease
    101681349 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    101681349 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101681349 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    101681349 (MAPK10)
   05415 Diabetic cardiomyopathy
    101681349 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101681349 (MAPK10)
   04936 Alcoholic liver disease
    101681349 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    101681349 (MAPK10)
   04931 Insulin resistance
    101681349 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101681349 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101681349 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mpuf01001]
    101681349 (MAPK10)
Enzymes [BR:mpuf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101681349 (MAPK10)
Protein kinases [BR:mpuf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101681349 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 101681349
NCBI-ProteinID: XP_004756195
Ensembl: ENSMPUG00000002290
UniProt: A0A8U0MU45
LinkDB
Position
Unknown
AA seq 464 aa
MSLHLLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttattgtactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcagggattcgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagttgacaaccagttctacagtgtggaagtgggagactcaaccttcacagtt
ctcaagcgctaccagaatttgaagcctattggctctggggctcagggaatagtttgtgct
gcgtatgatgctgttcttgacagaaatgtggccattaagaagctcagcagaccttttcag
aaccaaacgcatgccaagagagcttaccgggagctggtcctcatgaagtgtgtgaaccat
aagaacattattagtttattaaatgtcttcacaccccagaaaacattggaggagttccaa
gatgtttacttagtcatggaactgatggatgccaacttgtgtcaggtgattcagatggaa
ttagaccatgagcgaatgtcttacctgctataccaaatgttgtgtggcatcaagcacctt
cattctgctggaattattcacagggatttaaaaccaagtaacattgtagtcaagtctgat
tgtacattgaaaatcctcgactttggactggccaggacggcaggcacgagcttcatgatg
actccttatgtggtcacacgttattatagagcccccgaggttattctgggaatgggctac
aaggagaatgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtaattgagcaactagga
acaccatgtcctgaattcatgaagaaattgcaacctacagtaagaaactatgtggagaat
cggcccaagtatgcaggactcaccttccccaagctctttccagattccctcttcccagcg
gactctgagcacaataaactcaaagccagccaagccagggacttactgtcaaagatgcta
gtgatcgacccagcaaaaagaatatcggtggatgacgccttacagcatccttacatcaat
gtttggtatgaccctgccgaagtggaggcgcctccacctcagatttatgacaaacaattg
gatgaaagagaacacaccattgaagaatggaaagaacttatctacaaagaagtaatgaat
tcagaagaaaagactaaaaacggtgttgtaaaaggacaaccgtctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcttcgtccgtcaatgacatctcctccatgtcc
accgaccagaccctggcatctgacactgacagcagcctggaagcttcagcaggacccctg
ggttgttgcaggtga

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