KEGG   Mustela putorius furo (domestic ferret): 101681860
Entry
101681860         CDS       T07239                                 
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
  KO
K03099  son of sevenless
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf01521  EGFR tyrosine kinase inhibitor resistance
mpuf01522  Endocrine resistance
mpuf04010  MAPK signaling pathway
mpuf04012  ErbB signaling pathway
mpuf04014  Ras signaling pathway
mpuf04062  Chemokine signaling pathway
mpuf04068  FoxO signaling pathway
mpuf04072  Phospholipase D signaling pathway
mpuf04150  mTOR signaling pathway
mpuf04151  PI3K-Akt signaling pathway
mpuf04510  Focal adhesion
mpuf04540  Gap junction
mpuf04630  JAK-STAT signaling pathway
mpuf04650  Natural killer cell mediated cytotoxicity
mpuf04660  T cell receptor signaling pathway
mpuf04662  B cell receptor signaling pathway
mpuf04664  Fc epsilon RI signaling pathway
mpuf04714  Thermogenesis
mpuf04722  Neurotrophin signaling pathway
mpuf04810  Regulation of actin cytoskeleton
mpuf04910  Insulin signaling pathway
mpuf04912  GnRH signaling pathway
mpuf04915  Estrogen signaling pathway
mpuf04917  Prolactin signaling pathway
mpuf04926  Relaxin signaling pathway
mpuf04935  Growth hormone synthesis, secretion and action
mpuf05034  Alcoholism
mpuf05160  Hepatitis C
mpuf05161  Hepatitis B
mpuf05163  Human cytomegalovirus infection
mpuf05165  Human papillomavirus infection
mpuf05200  Pathways in cancer
mpuf05205  Proteoglycans in cancer
mpuf05206  MicroRNAs in cancer
mpuf05207  Chemical carcinogenesis - receptor activation
mpuf05208  Chemical carcinogenesis - reactive oxygen species
mpuf05210  Colorectal cancer
mpuf05211  Renal cell carcinoma
mpuf05213  Endometrial cancer
mpuf05214  Glioma
mpuf05215  Prostate cancer
mpuf05220  Chronic myeloid leukemia
mpuf05221  Acute myeloid leukemia
mpuf05223  Non-small cell lung cancer
mpuf05224  Breast cancer
mpuf05225  Hepatocellular carcinoma
mpuf05226  Gastric cancer
mpuf05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101681860 (SOS1)
   04012 ErbB signaling pathway
    101681860 (SOS1)
   04014 Ras signaling pathway
    101681860 (SOS1)
   04630 JAK-STAT signaling pathway
    101681860 (SOS1)
   04068 FoxO signaling pathway
    101681860 (SOS1)
   04072 Phospholipase D signaling pathway
    101681860 (SOS1)
   04151 PI3K-Akt signaling pathway
    101681860 (SOS1)
   04150 mTOR signaling pathway
    101681860 (SOS1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101681860 (SOS1)
   04540 Gap junction
    101681860 (SOS1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101681860 (SOS1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    101681860 (SOS1)
   04660 T cell receptor signaling pathway
    101681860 (SOS1)
   04662 B cell receptor signaling pathway
    101681860 (SOS1)
   04664 Fc epsilon RI signaling pathway
    101681860 (SOS1)
   04062 Chemokine signaling pathway
    101681860 (SOS1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101681860 (SOS1)
   04912 GnRH signaling pathway
    101681860 (SOS1)
   04915 Estrogen signaling pathway
    101681860 (SOS1)
   04917 Prolactin signaling pathway
    101681860 (SOS1)
   04926 Relaxin signaling pathway
    101681860 (SOS1)
   04935 Growth hormone synthesis, secretion and action
    101681860 (SOS1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101681860 (SOS1)
  09159 Environmental adaptation
   04714 Thermogenesis
    101681860 (SOS1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101681860 (SOS1)
   05206 MicroRNAs in cancer
    101681860 (SOS1)
   05205 Proteoglycans in cancer
    101681860 (SOS1)
   05207 Chemical carcinogenesis - receptor activation
    101681860 (SOS1)
   05208 Chemical carcinogenesis - reactive oxygen species
    101681860 (SOS1)
   05231 Choline metabolism in cancer
    101681860 (SOS1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101681860 (SOS1)
   05225 Hepatocellular carcinoma
    101681860 (SOS1)
   05226 Gastric cancer
    101681860 (SOS1)
   05214 Glioma
    101681860 (SOS1)
   05221 Acute myeloid leukemia
    101681860 (SOS1)
   05220 Chronic myeloid leukemia
    101681860 (SOS1)
   05211 Renal cell carcinoma
    101681860 (SOS1)
   05215 Prostate cancer
    101681860 (SOS1)
   05213 Endometrial cancer
    101681860 (SOS1)
   05224 Breast cancer
    101681860 (SOS1)
   05223 Non-small cell lung cancer
    101681860 (SOS1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    101681860 (SOS1)
   05160 Hepatitis C
    101681860 (SOS1)
   05163 Human cytomegalovirus infection
    101681860 (SOS1)
   05165 Human papillomavirus infection
    101681860 (SOS1)
  09165 Substance dependence
   05034 Alcoholism
    101681860 (SOS1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101681860 (SOS1)
   01522 Endocrine resistance
    101681860 (SOS1)
SSDB
Motif
Pfam: RasGEF RasGEF_N RhoGEF SOS1_NGEF_PH PH PH_10 PH_19 IQ_SEC7_PH RHG20_PH Takusan
Other DBs
NCBI-GeneID: 101681860
NCBI-ProteinID: XP_004765580
Ensembl: ENSMPUG00000010472
UniProt: A0A8U0N3N8
LinkDB
Position
Unknown
AA seq 1333 aa
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVSLPHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLPSITGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq 4002 nt   +upstreamnt  +downstreamnt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcacccaagtggcgg
gggctgctggtgccggcgctgaaaaaggtccaggggcaagttcatccaactcttgagtct
agtgatgatgctcttcaatatgttgaagaattaattttgcagttattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataagtgggcaatagctgatgcccagtcggctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttactaaaggaggtcctaggttat
aaaattgaccaccaggtctctgtttacatagtagcagtattagaatacatttctgcagac
attttaaagctggtggggaattatgtacgaaatatacggcattatgaaattacaaagcag
gatattaaagtggcaatgtgtgctgataaggtattaatggacatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagagccttccacctcaggagagcaaact
tactatgatttggtaaaagcatttatggcagaaattcgacagtacataagggaactaaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtagatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtggaaatgactgatgaaggtagcccccatcccttagtagga
agctgctttgaagacttagcagaggaactggcctttgatccatacgaatcatacgctcgc
gatatcttacggcctggttttcacgatcgtttccttagtcagttatcaaagcctggagca
gcactctatttacagtcaataggcgaaggcttcaaagaagctgttcagtatgttctgccc
aggctacttctagcccccgtttaccactgtctgcattactttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagattg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcaaaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaataccgtcttaaagaaaagtttttcatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagcc
ttgatatctttacaataccggagtacgctggagaggatgcttgatgtgacgatgctgcag
gaagagaaggaggagcagatgaggctccctagtgccgatgtttatagatttgcagagcct
gactctgaagagaatataatatttgaagaaaacatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaagctaatagagaggctcacataccatatgtatgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagcccacagaagctgatcgc
atagctatagagaatggagatcagcccttgagtgcagaactaaaaaggtttagaaaagaa
tacatacagcctgtacagctgcgagtattaaatgtatgtcggcattgggtagagcaccac
ttctatgattttgaaagggatgcagatcttttgcagcgaatggaagaatttattggaaca
gtgagaggtaaagctatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccacg
gttgagtggcatataagcaggcctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctatatagagctgtacaa
ccatcagaattagttggaagtgtgtggactaaagaagacaaagaaattaattctcctaat
ctcctaaaaatgatccggcataccacgaatctcactctgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgagtcgaatcattgagattctacaa
gtctttcaagagctgaacaacttcaatggtgtccttgaggttgtcagtgctatgaactcc
tcacctgtttacagactagatcacacatttgagcaaataccaagtcgccaaaagaaaatc
ttagaagaagctcatgaattaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttacctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcagatatcaaaaggttctttgaaaatttgaatccaatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctcttccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagcca
aggaaaattagttacagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcgtctggtgcttctagtaccaccgat
gtttgcagcgtttttgattccgatcattcgagcccttttcattcaagcagcgataccgtc
tttatccaagtttcactgccccatggcccaagatctgcttcagtatcatctataagttta
accaagggcactgatgaggtgcccgtcccccctcctgttcctccacgaagacggccggaa
tctgcccccgccgaatcttcgccatctaagattatgtctaagcatttggacagcccccca
gcaattcctcctaggcagcccacatcaaaagcctattcgccacgatactccatatcagac
cggacctctatatcagaccctcctgagagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctccagctcaccactacatctccagcctccccctttgggcaaa
aaaagcgatcatggcaatgccttcttcccaaatagcccttccccttttacaccacctcct
cctcaaacaccctctcctcatggcacaagaaggcacttgccgtcgccaccactgacacaa
gaagtggaccttccttccatcaccgggccgcctgttcctccacgacaaagcacttctcag
catatccctaaactccctccaaaaacttataaaagggagcacacgcacccatccatgcac
agagatggacccccactgttggagaatgcccattcctcctga

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