Mustela putorius furo (domestic ferret): 101681913 Help Entry 101681913         CDS       T07239                                  Symbol TOP2B Name (RefSeq) DNA topoisomerase 2-beta   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism mpuf  Mustela putorius furo (domestic ferret) Pathway mpuf01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:mpuf00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     101681913 (TOP2B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:mpuf03032]     101681913 (TOP2B)    03036 Chromosome and associated proteins [BR:mpuf03036]     101681913 (TOP2B) Enzymes [BR:mpuf01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      101681913 (TOP2B) DNA replication proteins [BR:mpuf03032]  Eukaryotic type   DNA Topoisomerases    101681913 (TOP2B) Chromosome and associated proteins [BR:mpuf03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     101681913 (TOP2B)   Centrosome formation proteins    Centriole proteins     101681913 (TOP2B) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c DUF7180 Microp_apicomplexa_20 Motif Other DBs NCBI-GeneID:  101681913 NCBI-ProteinID:  XP_012912633 Ensembl:  ENSMPUG00000012113 UniProt:  M3YL11 LinkDB All DBs Position Unknown AA seq 1542 aa AA seqDB search MWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWN NGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE TACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMT RRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVC LTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHI WVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQ TQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDR YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMT DQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKK HIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDD RKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVD GFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNN INLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAVDDNLLKFLYDDNQRVEPEW YIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQ ELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEY HTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILK EFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQR GYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEE LIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMAGKAIKGKVG KPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKKGDLDTTAVKVEFDEEFSGT PVEGTGEEALISSAPVNKGPKPKREKKEPGTRVRKTPTSSGKSSAKKVKKRNPWSDDESK SESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDLEELKVKASPI TNDGEDEFIPSDGLDKDEYTFSPGKSKATPEKSSHDKKSQDFGNLFSFPSYSQKSEDDSA KFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTTAKPKRAPKQKKVEPINSD SDSEFGIPKKTTPLKGKGRGAKKRKASGSENEGDYNPGRKTSKTTSKKLKKTSFDQDSDV DIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN NT seq 4629 nt NT seq  +upstreamnt  +downstreamnt atgtgggtatatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggt ttatacaagatctttgatgaaattttggtcaatgcagctgacaataaacagagggacaag aatatgacttgtattaaagtttctattgatcctgaatcaaatattataagcatttggaat aatgggaaaggcattccagtagtggaacacaaagtagagaaagtatatgttcctgcgtta atttttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggt ggtcgcaatggttatggtgcaaaactttgtaatattttcagtacaaaatttacagtagaa actgcttgcaaagaatacaaacacagttttaagcagacatggatgaataacatgatgaag acttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattccaa ccagatctgtctaaatttaagatggaaaaacttgacaaggatattgtggcccttatgacc agaagagcttatgatttggctggttcatgcaagggtgtcaaggtcatgtttaatggaaag aaattgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaagttggat gaaactggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgt ctcacactgagtgaaaagggattccagcaaatcagctttgtaaatagtattgcaacaaca aaaggtggacgtcatgtggattatgtagtagatcaagttgttggtaaactgattgaagta gttaagaaaaagaacaaagccggtgtatcagtaaaaccatttcaagtaaaaaaccatata tgggtttttattaactgccttatcgaaaatccaacttttgattctcaaactaaggaaaac atgactctgcaacccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaa gcagcttctaactgtggcattgtagaaagtattctgaattgggtgaaatttaaggcccag actcagctgaacaagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaaa ctggatgatgctaatgatgctggtggcaaacattccctggagtgtacactgatactaacc gagggagactctgccaaatcattggctgtgtctggattaggtgtgattgggcgagacaga tatggagtctttccacttaggggaaaaattcttaacgtacgggaagcttctcataaacag atcatggaaaatgcagaaataaacaatattatcaaaatagttggtctacagtacaagaaa agttatgatgatgcagaatctctgaaaactttacgctatgggaagattatgattatgact gatcaggatcaagatggttctcacataaaaggtctgcttattaatttcatccatcacaat tggccatcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggct agcaaaaataaacaggaactttccttctatagtattcctgaatttgatgagtggaaaaaa catatagaaaaccagaaagcctggaaaataaaatactacaaagggttgggtaccagtaca gctaaagaagcaaaggaatattttgctgatatggaaaggcaccgcatcttatttagatat gctggtcctgaagatgatgctgccattaccttggcattcagtaaaaagaagattgatgat agaaaagaatggttaacaaattttatggaagaccggagacagcgtaggttacatggctta ccagagcaatttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaac aaggaattgattctcttctcaaattcagacaatgaaagatctataccatctcttgttgat ggatttaaaccaggacaacgaaaagttttatttacttgtttcaagaggaatgataaacgt gaagtaaaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatgga gagcaagcattgatgatgactattgtgaatttggctcagaactttgtgggaagcaacaac attaatttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgct gcaagccctcgttatattttcacaatgttaagctctttatcaagattgctttttcctgct gtggacgacaacctgcttaaattcctttatgatgataatcaacgtgttgagcctgagtgg tatattcctataattcccatggttttaataaatggtgctgagggcattggtactggatgg gcttgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgcta gatggcttggatcctcatcctatgcttccaaactacaaaaactttaaaggaaccatccaa gagcttggtcaaaaccagtatgcagtcagtggtgaaatatttgtggtggatagaaacaca gtagagattacagagcttccagttagaacttggacacaggtatacaaagaacaggtttta gaaccaatgctcaatggaacagataaaacaccagcattaatttctgattataaagaatat catactgatacaactgtgaaatttgtggtgaaaatgactgaagagaagcttgcacaagca gaagctgctggattgcacaaagtttttaaacttcagactactcttacttgtaattccatg gtactctttgatcatatgggatgtctcaagaagtatgaaactgttcaagacatcttgaaa gaattctttgatttacgattaagttactatggtttacgtaaggaatggcttgtaggaatg ttgggagcagagtccacaaagcttaacaatcaagcccgtttcattttagagaagatacaa ggaaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagaga ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagag gaagaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggcccc gattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaa ctgattaaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctcct tcagatctttggaaagaagacttagcagcatttgttgaagaactggataaagtggaagca caagaacgggaggatattctggctggaatggcaggaaaagcaataaaaggtaaagttggc aaacctaaggtgaagaaacttcaactggaagagacaatgccctcaccttatgggagaaga atagttcctgaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaagaaa aagggtgatcttgataccacagcggtaaaagtagaatttgatgaagaatttagtggaaca ccggtagagggtactggagaagaggcattgatctcgtcagctcctgtaaataaaggtccc aaacccaaaagggaaaaaaaggaacctggcaccagggtgagaaaaacacctacatcctct ggtaaatccagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaag tcagaaagtgacctggaagaaacagaacctgtggttattccaagagattctttacttagg agagcagctgcggaaaggcctaagtacacatttgatttctcagaggaagaggatgatgat gctgatgatgatgatgataataatgatttagaggagttgaaagttaaagcatctcctata acaaatgatggggaagatgaatttattccttcagatggcctagataaagatgaatataca ttttcaccaggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaagtcaa gattttgggaatctcttctcatttccttcgtactctcagaagtcagaagatgattcagct aaatttgacagtaatgaagaagattctgcctctgtattttcaccatcatttggtctgaaa caaacagataaggttccaagtaaaactgtagctgctaaaaagggcaaaccatcttcagat acaactgctaagcccaagagagcccctaaacagaaaaaagtagagcctatcaactctgat tcagattcagaatttggcattccaaagaagactacacccctaaaaggtaaaggccgaggg gcaaagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaa acatccaaaacaacaagcaagaaactgaagaaaacatcttttgatcaggattcagatgtg gacatcttcccatcagacttcacttctgaaccgccttctctgccacggaccggtagggct aggaaagaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatg tttaattaa

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