Mustela putorius furo (domestic ferret): 101681935
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Entry
101681935 CDS
T07239
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
mpuf
Mustela putorius furo (domestic ferret)
Pathway
mpuf01521
EGFR tyrosine kinase inhibitor resistance
mpuf01522
Endocrine resistance
mpuf04010
MAPK signaling pathway
mpuf04014
Ras signaling pathway
mpuf04015
Rap1 signaling pathway
mpuf04066
HIF-1 signaling pathway
mpuf04068
FoxO signaling pathway
mpuf04114
Oocyte meiosis
mpuf04140
Autophagy - animal
mpuf04144
Endocytosis
mpuf04150
mTOR signaling pathway
mpuf04151
PI3K-Akt signaling pathway
mpuf04152
AMPK signaling pathway
mpuf04211
Longevity regulating pathway
mpuf04213
Longevity regulating pathway - multiple species
mpuf04510
Focal adhesion
mpuf04520
Adherens junction
mpuf04550
Signaling pathways regulating pluripotency of stem cells
mpuf04730
Long-term depression
mpuf04913
Ovarian steroidogenesis
mpuf04914
Progesterone-mediated oocyte maturation
mpuf05200
Pathways in cancer
mpuf05202
Transcriptional misregulation in cancer
mpuf05205
Proteoglycans in cancer
mpuf05214
Glioma
mpuf05215
Prostate cancer
mpuf05218
Melanoma
mpuf05224
Breast cancer
mpuf05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
mpuf00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101681935 (IGF1R)
04014 Ras signaling pathway
101681935 (IGF1R)
04015 Rap1 signaling pathway
101681935 (IGF1R)
04066 HIF-1 signaling pathway
101681935 (IGF1R)
04068 FoxO signaling pathway
101681935 (IGF1R)
04151 PI3K-Akt signaling pathway
101681935 (IGF1R)
04152 AMPK signaling pathway
101681935 (IGF1R)
04150 mTOR signaling pathway
101681935 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101681935 (IGF1R)
04140 Autophagy - animal
101681935 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
101681935 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101681935 (IGF1R)
04520 Adherens junction
101681935 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
101681935 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101681935 (IGF1R)
04914 Progesterone-mediated oocyte maturation
101681935 (IGF1R)
09156 Nervous system
04730 Long-term depression
101681935 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
101681935 (IGF1R)
04213 Longevity regulating pathway - multiple species
101681935 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101681935 (IGF1R)
05202 Transcriptional misregulation in cancer
101681935 (IGF1R)
05205 Proteoglycans in cancer
101681935 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101681935 (IGF1R)
05214 Glioma
101681935 (IGF1R)
05218 Melanoma
101681935 (IGF1R)
05215 Prostate cancer
101681935 (IGF1R)
05224 Breast cancer
101681935 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101681935 (IGF1R)
01522 Endocrine resistance
101681935 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mpuf01001
]
101681935 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mpuf04090
]
101681935 (IGF1R)
Enzymes [BR:
mpuf01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101681935 (IGF1R)
Protein kinases [BR:
mpuf01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
101681935 (IGF1R)
CD molecules [BR:
mpuf04090
]
Proteins
101681935 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
DUF4476
Motif
Other DBs
NCBI-GeneID:
101681935
NCBI-ProteinID:
XP_004759866
Ensembl:
ENSMPUG00000010753
UniProt:
M3YH59
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACKHYYYSGVCVPTCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHN
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLQGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRGRNTTVVDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSVKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
AGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccgggcattgacatccgc
aatgactatcagcagctaaagcgcctggagaactgcacggtgatcgaaggctacctccac
atcctgctcatctccaaggcagaggactaccgcagctaccgtttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctcgagagcctcggggacctcttc
cccaacctcacagtcatccgcggctggaaactcttctacaactatgccctggtcatcttt
gagatgaccaatctcaaggatatcggactttacaatctgaggaacatcacccggggggcc
atcaggattgagaagaatgccgatctctgttacctctccacggtggactggtccctgatc
ctggatgccgtgtccaataactacatcgtggggaacaagcccccgaaggagtgcggggac
ctgtgtccggggacgatggaggagaagcccttgtgcgagaagacgaccatcaacaacgag
tacaactatcgctgctggaccaccaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgcgcgtgcaccgagaacaacgagtgctgtcaccccgagtgtttgggcagctgcagc
gcgcccgacaacgacacggcctgcgtcgcctgcaagcattactactactccggcgtgtgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccaatgccgagagcagcgactcggaggggttcgtcatccacaac
ggcgaatgcatgcaggagtgcccctctggcttcatccggaacggcagtcagagcatgtac
tgcataccttgtgaaggtccttgccccaaggtctgcgaggaagaaaagaaaacaaagacc
attgattcggttacctctgctcagatgctccaaggatgcaccatcttcaagggaaatttg
ctcattaatatccgccgaggcaataacattgcctcagaactggagaacttcatggggctc
attgaggtggtgacaggctacgtgaagatccgccattctcatgccttggtctccttgtcc
ttcctaaaaaaccttcgccagatcttaggagaggagcaacttgaggggaactactccttc
tatgtcctcgacaaccagaacttgcagcagctgtgggactgggaccatcgcaacctgacc
atcaaagctgggaagatgtactttgctttcaatcccaaattgtgcgtgtccgagatttac
cgcatggaggaggtgacggggacaaaaggacgccagagcaaaggggacataaacaccagg
aacaacggagaacgagcctcttgtgaaagcgacgtcctgcacttcacctctacgaccaca
tggaagaaccgcatcatcataacgtggcaccgttaccggccccctgactacagggacctc
atcagcttcactgtctactacaaggaagcaccttttaaaaacgtcacggagtatgacggg
caggatgcctgtggctccaacagctggaacatggtagatgtggacctccctcccaacaag
gatgtcgagcctggcattttactgcaaggactaaagccctggacacagtacgcggtgtat
gtcaaggcggtgaccctcaccatggtggagaatgaccacatccgtggggccaagagtgaa
atcttgtacattcgcaccaatgcttcagttccttccattcccctggatgttctctccgca
tccaactcctcttcccagctcatcgtaaagtggaacccgccgtccctgcccaacggcaac
ctcagttactacattgtgaggtggcaacggcagccacaggacagctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtacgccgacggcaccatcgacatc
gaggaggtgacggagaatcccaagactgaggtgtgcggcggagagaaggggccttgctgc
gcctgccccaaaacggaggccgagaagcaggctgagaaggaggaggccgagtaccgcaaa
gtctttgagaacttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gacgtcacacaagtcaccaacaccaccatgtccagccgaggcaggaacaccacagtggtg
gacacctataatatcacagacccagaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtaatctccaacctgcggcctttcactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctgggctgcagtgcctccaacttt
gtttttgcaagaaccatgcctgcagaaggggcagatgacattcctgggcctgtgacctgg
gagtcgaggcctgaaaactccatctttctcaagtggccagaacctgagaatcccaacgga
ttgattctcatgtatgaaataaaatacggatcacaagtcgaggaccagcgggagtgcgta
tcaagacaggagtacaggaagtatgggggcgccaagcttaaccggctcaacccggggaac
tacacggcccggatccaggccacctctctctccgggaatgggtcctggacagacccggtg
ttcttctatgtcccagccaaaataacgtacgaaaacttcatccacctgatcatcgctctg
cccgtcgctgtcctgctgatagtgggggggcttgtgataatgctgtacgtcttccacagg
aaaaggaataacagcaggctgggcaatggagtgctgtatgcttctgtgaacccagagtac
ttcagcgccgccgacgtgtacgtgcctgacgagtgggaggtcgctcgagagaagatcacc
atgagccgcgagttggggcaaggctccttcgggatggtgtacgaaggagttgccaaaggc
gtggttaaagatgagcccgagaccagggtggccattaaaacagtgaacgaggccgccagc
atgcgtgaaaggattgaatttctcaatgaggcttcagtgatgaaggagttcaactgccac
cacgtggtgcggttgctgggcgtggtgtcccagggccagccgacgctggtcatcatggaa
ctgatgactcggggcgatctcaaaagctatctccggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggggagattgca
gacggcatggcatacctcaacgccaacaagtttgtccacagagacctggccgcccggaac
tgcatggtggccgaagatttcacagtcaaaatcggagattttggtatgacgagagacatc
tacgagacagactattaccggaaaggaggaaaggggctgctgcctgtgcgctggatgtcc
cccgagtctctcaaggatggagtcttcaccactcactctgacgtctggtcctttggggtc
gtgctctgggagatcgccacgctggccgagcagccctaccagggcttgtccaacgagcag
gtccttcgcttcgttatggagggcggccttctggacaagccggacaactgtcccgacatg
ctgttcgagctgatgcgcatgtgctggcagtacaaccccaagatgaggccctccttcctg
gagatcatcagcagcgtcaaggacgagatggagcccggcttccgggaggtgtccttctac
tacagcgaggagaacaagccgcccgagccggaggagctggacctggagcccgagaacatg
gagagcgtccccctggacccctccgcctcctcttcctccctgccgctgcccgacagacac
gcaggacacaaggccgagaacggcccaggccctggcgtgctggtgctccgagccagcttc
gacgagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgcct
ctgccccagtcttcgacctgctga
DBGET
integrated database retrieval system
