Mustela putorius furo (domestic ferret): 101685824 Help Entry 101685824         CDS       T07239                                  Symbol EGFR Name (RefSeq) epidermal growth factor receptor   KO K04361   epidermal growth factor receptor [EC:2.7.10.1] Organism mpuf  Mustela putorius furo (domestic ferret) Pathway mpuf01521   EGFR tyrosine kinase inhibitor resistance mpuf01522   Endocrine resistance mpuf03272   Virion - Hepatitis viruses mpuf04010   MAPK signaling pathway mpuf04012   ErbB signaling pathway mpuf04014   Ras signaling pathway mpuf04015   Rap1 signaling pathway mpuf04020   Calcium signaling pathway mpuf04066   HIF-1 signaling pathway mpuf04068   FoxO signaling pathway mpuf04072   Phospholipase D signaling pathway mpuf04144   Endocytosis mpuf04151   PI3K-Akt signaling pathway mpuf04510   Focal adhesion mpuf04520   Adherens junction mpuf04540   Gap junction mpuf04630   JAK-STAT signaling pathway mpuf04810   Regulation of actin cytoskeleton mpuf04912   GnRH signaling pathway mpuf04915   Estrogen signaling pathway mpuf04921   Oxytocin signaling pathway mpuf04926   Relaxin signaling pathway mpuf04928   Parathyroid hormone synthesis, secretion and action mpuf04934   Cushing syndrome mpuf05160   Hepatitis C mpuf05163   Human cytomegalovirus infection mpuf05165   Human papillomavirus infection mpuf05171   Coronavirus disease - COVID-19 mpuf05200   Pathways in cancer mpuf05205   Proteoglycans in cancer mpuf05206   MicroRNAs in cancer mpuf05207   Chemical carcinogenesis - receptor activation mpuf05208   Chemical carcinogenesis - reactive oxygen species mpuf05210   Colorectal cancer mpuf05212   Pancreatic cancer mpuf05213   Endometrial cancer mpuf05214   Glioma mpuf05215   Prostate cancer mpuf05218   Melanoma mpuf05219   Bladder cancer mpuf05223   Non-small cell lung cancer mpuf05224   Breast cancer mpuf05225   Hepatocellular carcinoma mpuf05226   Gastric cancer mpuf05230   Central carbon metabolism in cancer mpuf05231   Choline metabolism in cancer mpuf05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:mpuf00001]  09120 Genetic Information Processing   09125 Information processing in viruses    03272 Virion - Hepatitis viruses     101685824 (EGFR)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101685824 (EGFR)    04012 ErbB signaling pathway     101685824 (EGFR)    04014 Ras signaling pathway     101685824 (EGFR)    04015 Rap1 signaling pathway     101685824 (EGFR)    04630 JAK-STAT signaling pathway     101685824 (EGFR)    04066 HIF-1 signaling pathway     101685824 (EGFR)    04068 FoxO signaling pathway     101685824 (EGFR)    04020 Calcium signaling pathway     101685824 (EGFR)    04072 Phospholipase D signaling pathway     101685824 (EGFR)    04151 PI3K-Akt signaling pathway     101685824 (EGFR)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     101685824 (EGFR)   09144 Cellular community - eukaryotes    04510 Focal adhesion     101685824 (EGFR)    04520 Adherens junction     101685824 (EGFR)    04540 Gap junction     101685824 (EGFR)   09142 Cell motility    04810 Regulation of actin cytoskeleton     101685824 (EGFR)  09150 Organismal Systems   09152 Endocrine system    04912 GnRH signaling pathway     101685824 (EGFR)    04915 Estrogen signaling pathway     101685824 (EGFR)    04921 Oxytocin signaling pathway     101685824 (EGFR)    04926 Relaxin signaling pathway     101685824 (EGFR)    04928 Parathyroid hormone synthesis, secretion and action     101685824 (EGFR)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101685824 (EGFR)    05206 MicroRNAs in cancer     101685824 (EGFR)    05205 Proteoglycans in cancer     101685824 (EGFR)    05207 Chemical carcinogenesis - receptor activation     101685824 (EGFR)    05208 Chemical carcinogenesis - reactive oxygen species     101685824 (EGFR)    05230 Central carbon metabolism in cancer     101685824 (EGFR)    05231 Choline metabolism in cancer     101685824 (EGFR)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     101685824 (EGFR)   09162 Cancer: specific types    05210 Colorectal cancer     101685824 (EGFR)    05212 Pancreatic cancer     101685824 (EGFR)    05225 Hepatocellular carcinoma     101685824 (EGFR)    05226 Gastric cancer     101685824 (EGFR)    05214 Glioma     101685824 (EGFR)    05218 Melanoma     101685824 (EGFR)    05219 Bladder cancer     101685824 (EGFR)    05215 Prostate cancer     101685824 (EGFR)    05213 Endometrial cancer     101685824 (EGFR)    05224 Breast cancer     101685824 (EGFR)    05223 Non-small cell lung cancer     101685824 (EGFR)   09172 Infectious disease: viral    05160 Hepatitis C     101685824 (EGFR)    05171 Coronavirus disease - COVID-19     101685824 (EGFR)    05163 Human cytomegalovirus infection     101685824 (EGFR)    05165 Human papillomavirus infection     101685824 (EGFR)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     101685824 (EGFR)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101685824 (EGFR)    01522 Endocrine resistance     101685824 (EGFR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mpuf01001]     101685824 (EGFR)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:mpuf04147]     101685824 (EGFR) Enzymes [BR:mpuf01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      101685824 (EGFR) Protein kinases [BR:mpuf01001]  Receptor tyrosine kinases (RTK)   EGFR family [OT]    101685824 (EGFR) Exosome [BR:mpuf04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    101685824 (EGFR)   Exosomal proteins of pancreatic cancer cells    101685824 (EGFR)   Exosomal proteins of bladder cancer cells    101685824 (EGFR) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like Borrelia_P83 ABC1 Motif Other DBs NCBI-GeneID:  101685824 NCBI-ProteinID:  XP_004739433 Ensembl:  ENSMPUG00000018153 UniProt:  M3Z380 LinkDB All DBs Position Unknown AA seq 1207 aa AA seqDB search MRPSGTAGAALLVLLAAHFPASPALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMFNNCEV VLGNLEITYMQKNYDLSFLKTIQEVAGYVLIALNTVEKIPLENLQIIRGNVLYENMHALS VLSNYGTNKTGLQELPLRNLHEILQGAVRFSNNPVLCNVDSIKWQDIVDDSFVSNMSMDF QNHAGNCQKCDPSCPNGSCWGPGKENCQKLTKIICAQQCSGRCRGRSPSDCCHNQCAAGC TGPRESDCLVCRKFRDETTCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV VTDHGSCVRACSSDSYEVEEDGVRKCKKCEGPCRKVCNGIGIGEFKDTLSINATNIKHFK NCTSISGDLHILPVAFRGDSFTRTLPLDPKELDILKTVKEITGFLLIQAWPENRTDLHAF ENLEIIRGRTKQHGQFSLAVVGLDITSLGLRSLKEISDGDVIISGNKKLCYANTINWKKL FGTSSQKTKIINNKDEKGCKAMGHVCHPLCSSEGCWGPEPKDCVSCRNVSRGKECVEKCN VLEGEPREFVENSECIQCHPECLPQPMNVTCTGRGPDSCVKCAHYIDGPHCVKTCPAGIM GENNTLVWKFADANRVCHLCHSNCTYGCDGPGLEGCTIEGNKIPPIAIGIVGGLFLVVMV ALGVGLFLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY GVTVWELMTFGSKPYDGIPASEISTILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMEDVVDADEYLIPQ QGFFHSPSTSRTPLLSSLSATSNNSTVACIDRNGSCPLKEDSFLQRYSSDPTGTLTEDNI DDTFLPAPEYINQSVPKRPAGSVQNPVYHNQPLNPAPGRDAHYQNPHSNAVGNPEYLNTV PPGITSALGGPGLWAQKDNHQISLDNPDYQQHFFPKEAKSNGVFKGPAAEHADYLRVAPP SSEFIGA NT seq 3624 nt NT seq  +upstreamnt  +downstreamnt atgcgaccctccgggaccgcgggagccgcgctcctggtcctgctggccgcgcacttcccg gcgagtccggcgctggaggagaagaaagtttgccaaggcacgagtaaccggctcacccag ctgggcacttttgaagaccacttcctgagccttcagaggatgttcaataactgtgaggtg gtccttgggaatctggaaattacctacatgcaaaagaattacgacctttccttcttaaag accatccaggaagttgccggctatgtcctcattgccctgaacaccgtggagaagattccc ttggaaaacctgcagatcatccgaggaaacgtgctctatgaaaacatgcatgccttgtcc gtcttatccaactacggcacgaacaaaaccgggctgcaggagcttcccctgagaaactta catgaaatcctccagggcgccgtgcgcttcagcaacaaccctgtcctctgcaacgtggac agcatcaagtggcaggacatcgtggacgacagttttgtaagcaacatgtcaatggacttc cagaaccatgcgggcaattgccaaaagtgtgatccgagctgtcccaatggaagttgttgg ggtccgggaaaggagaattgccagaaattgaccaaaatcatctgtgcccagcagtgttcg gggcgctgccgcggcaggtcccccagcgactgctgtcacaaccagtgtgccgccggctgc acagggccccgcgagagcgactgtctggtgtgccgcaagttccgcgacgaaaccacgtgc aaggacacctgcccgccgctcatgctctacaacccgaccacctaccagatggacgtcaac ccagagggaaaatacagctttggtgctacctgcgtgaagaagtgcccccgtaactacgtg gtgaccgaccacggctcgtgtgtccgagcctgcagctccgacagctacgaggtagaggaa gatggagtccgcaagtgtaagaagtgtgaggggccttgccgcaaagtgtgtaatggaata ggcattggcgaatttaaagacacgctttccataaatgctacaaatattaaacacttcaaa aattgcacgtcaatcagcggagatcttcatatcttgcctgtagcgtttagaggtgactcc ttcacgcgtactctgcctctcgatccaaaggaactggacattctaaaaactgtaaaggaa ataacagggtttctgctgattcaggcctggcctgaaaacagaactgacctccatgctttt gagaacctagaaatcatacgtggaagaacaaagcaacatggtcagttttctcttgcggtc gtcggcctggacataacgtccttgggtttacgctccctcaaggagatcagtgatggggat gtgatcatctcgggaaacaaaaaattgtgctatgcgaatacaataaactggaaaaaacta tttgggacttcaagtcagaaaaccaaaattataaacaacaaagatgaaaaaggctgcaag gccatgggccacgtctgccatcctttgtgctcatcagagggctgctggggcccagagccg aaagactgtgtgtcctgcagaaacgtcagccggggcaaggaatgtgtggagaagtgcaat gttctggagggggagccaagggagtttgtggagaactccgagtgtatacagtgccatccg gaatgcctgccccagcccatgaatgtaacctgcacgggacggggaccggacagctgtgtc aagtgtgcgcactacatcgacggcccgcactgcgtcaagacctgtccggctggcatcatg ggagagaacaacaccctggtctggaagtttgcagacgccaatcgcgtgtgccacctgtgt cattccaactgtacctatggctgtgacgggccaggtcttgaaggctgtacgatagaaggg aacaagatcccacccattgccattgggattgtgggcggccttttcttggtggtgatggtg gccctcggggtgggcctctttttgcgccggcgccatattgtccggaagcgaacccttcgt agactgctgcaagaaagagagcttgttgagcctcttacgcccagcggagaagctcccaac caagctctcttgaggatcttaaaggaaacagaattcaaaaagatcaaggtgctgggctct ggagcatttggcacggtgtacaagggactctggatcccagaaggtgagaaggttaaaatt cccgtggccatcaaggaattaagagaagccacatctccgaaagccaacaaggaaattctt gatgaagcctacgtgatggccagtgtggacaatccacatgtctgccgcctcctgggcatc tgcctcacctccacagtccagctgatcacacagctcatgccctttggctgcctcctggac tacgtccgcgagcacaaggacaacatcggctcccagtacctgctcaactggtgtgtgcag attgcaaagggcatgaactacctagaggaccggcgcttggtgcaccgcgacctggcagcc agaaatgtcctggtgaagaccccacagcacgtcaagatcacagattttgggctggccaag ctgcttggtgccgaggagaaagaataccatgcggaaggaggcaaggtgcctatcaagtgg atggctttggaatcaattttacaccgaatttatacccaccaaagtgatgtgtggagctac ggggtcactgtttgggagttgatgaccttcgggtccaagccttatgacggaatccccgcc agcgagatctccaccatcctggagaaaggagaacgcctcccgcagccgcccatatgcacc atcgatgtctacatgatcatggtcaagtgctggatgatagatgcagacagtcgccccaaa ttccgtgagctgatcattgaattctccaaaatggcccgagacccccagcgctaccttgtc atccagggagatgagagaatgcacttgccgagccctacagactccaatttttaccgcgca ctgatggacgaagaggacatggaggatgtggtggacgctgatgagtacctcatcccccag cagggcttcttccacagcccctccacgtcccggacccccctcctgagctctctgagcgcc accagcaacaactccaccgtggcttgcattgacagaaatgggagctgtcctctcaaagaa gacagcttcctacagcggtacagctcagaccccactggcaccttgactgaggacaacata gatgacactttcctcccagcacccgaatacataaaccagtccgtccccaagaggccggca ggttccgtgcagaatccggtctatcataatcagcctctaaacccagctcctggcagagac gctcactaccaaaacccccacagcaatgccgtgggcaaccctgagtatctcaacactgtc cctcccggcatcaccagcgcgcttggtggccccggcctctgggcccagaaagacaaccac cagatcagcctggacaaccccgactaccagcagcatttctttcccaaggaagccaagtcc aacggcgtcttcaagggccctgcagccgaacatgcagactacctgcgggtagccccgccg agcagtgagtttattggagcgtga

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