KEGG   Mustela putorius furo (domestic ferret): 101686271
Entry
101686271         CDS       T07239                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf01522  Endocrine resistance
mpuf04010  MAPK signaling pathway
mpuf04015  Rap1 signaling pathway
mpuf04068  FoxO signaling pathway
mpuf04071  Sphingolipid signaling pathway
mpuf04114  Oocyte meiosis
mpuf04148  Efferocytosis
mpuf04218  Cellular senescence
mpuf04261  Adrenergic signaling in cardiomyocytes
mpuf04370  VEGF signaling pathway
mpuf04380  Osteoclast differentiation
mpuf04550  Signaling pathways regulating pluripotency of stem cells
mpuf04611  Platelet activation
mpuf04613  Neutrophil extracellular trap formation
mpuf04620  Toll-like receptor signaling pathway
mpuf04621  NOD-like receptor signaling pathway
mpuf04622  RIG-I-like receptor signaling pathway
mpuf04625  C-type lectin receptor signaling pathway
mpuf04657  IL-17 signaling pathway
mpuf04658  Th1 and Th2 cell differentiation
mpuf04659  Th17 cell differentiation
mpuf04660  T cell receptor signaling pathway
mpuf04664  Fc epsilon RI signaling pathway
mpuf04668  TNF signaling pathway
mpuf04670  Leukocyte transendothelial migration
mpuf04714  Thermogenesis
mpuf04722  Neurotrophin signaling pathway
mpuf04723  Retrograde endocannabinoid signaling
mpuf04728  Dopaminergic synapse
mpuf04750  Inflammatory mediator regulation of TRP channels
mpuf04912  GnRH signaling pathway
mpuf04914  Progesterone-mediated oocyte maturation
mpuf04917  Prolactin signaling pathway
mpuf04926  Relaxin signaling pathway
mpuf04932  Non-alcoholic fatty liver disease
mpuf04933  AGE-RAGE signaling pathway in diabetic complications
mpuf04935  Growth hormone synthesis, secretion and action
mpuf04936  Alcoholic liver disease
mpuf05014  Amyotrophic lateral sclerosis
mpuf05020  Prion disease
mpuf05022  Pathways of neurodegeneration - multiple diseases
mpuf05132  Salmonella infection
mpuf05133  Pertussis
mpuf05135  Yersinia infection
mpuf05140  Leishmaniasis
mpuf05142  Chagas disease
mpuf05145  Toxoplasmosis
mpuf05152  Tuberculosis
mpuf05161  Hepatitis B
mpuf05163  Human cytomegalovirus infection
mpuf05167  Kaposi sarcoma-associated herpesvirus infection
mpuf05169  Epstein-Barr virus infection
mpuf05170  Human immunodeficiency virus 1 infection
mpuf05171  Coronavirus disease - COVID-19
mpuf05205  Proteoglycans in cancer
mpuf05208  Chemical carcinogenesis - reactive oxygen species
mpuf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mpuf05415  Diabetic cardiomyopathy
mpuf05417  Lipid and atherosclerosis
mpuf05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101686271 (MAPK12)
   04015 Rap1 signaling pathway
    101686271 (MAPK12)
   04370 VEGF signaling pathway
    101686271 (MAPK12)
   04668 TNF signaling pathway
    101686271 (MAPK12)
   04068 FoxO signaling pathway
    101686271 (MAPK12)
   04071 Sphingolipid signaling pathway
    101686271 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    101686271 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    101686271 (MAPK12)
   04218 Cellular senescence
    101686271 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    101686271 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101686271 (MAPK12)
   04613 Neutrophil extracellular trap formation
    101686271 (MAPK12)
   04620 Toll-like receptor signaling pathway
    101686271 (MAPK12)
   04621 NOD-like receptor signaling pathway
    101686271 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    101686271 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    101686271 (MAPK12)
   04660 T cell receptor signaling pathway
    101686271 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    101686271 (MAPK12)
   04659 Th17 cell differentiation
    101686271 (MAPK12)
   04657 IL-17 signaling pathway
    101686271 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    101686271 (MAPK12)
   04670 Leukocyte transendothelial migration
    101686271 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101686271 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    101686271 (MAPK12)
   04917 Prolactin signaling pathway
    101686271 (MAPK12)
   04926 Relaxin signaling pathway
    101686271 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    101686271 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101686271 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    101686271 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    101686271 (MAPK12)
   04722 Neurotrophin signaling pathway
    101686271 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101686271 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101686271 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    101686271 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101686271 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    101686271 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101686271 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101686271 (MAPK12)
   05161 Hepatitis B
    101686271 (MAPK12)
   05171 Coronavirus disease - COVID-19
    101686271 (MAPK12)
   05163 Human cytomegalovirus infection
    101686271 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101686271 (MAPK12)
   05169 Epstein-Barr virus infection
    101686271 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101686271 (MAPK12)
   05135 Yersinia infection
    101686271 (MAPK12)
   05133 Pertussis
    101686271 (MAPK12)
   05152 Tuberculosis
    101686271 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101686271 (MAPK12)
   05140 Leishmaniasis
    101686271 (MAPK12)
   05142 Chagas disease
    101686271 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101686271 (MAPK12)
   05020 Prion disease
    101686271 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    101686271 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101686271 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    101686271 (MAPK12)
   05415 Diabetic cardiomyopathy
    101686271 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101686271 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    101686271 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101686271 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101686271 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mpuf01001]
    101686271 (MAPK12)
Enzymes [BR:mpuf01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101686271 (MAPK12)
Protein kinases [BR:mpuf01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101686271 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 101686271
NCBI-ProteinID: XP_012902728
Ensembl: ENSMPUG00000002323
UniProt: M3XT99
LinkDB
Position
Unknown
AA seq 287 aa
MRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLMKHEKLSEDRIQFLVYQMLKG
LKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADSEMTGYVVTRWYRAPEVILNW
TRYTQTVDIWSAGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRLQSADAKN
YMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAERRVTAAEALTHPYFESLQDTEDE
PTAQKYDESFDDMDHTLDDWKRVTYKEVLSFKPPRQLGTKVSKETAL
NT seq 864 nt   +upstreamnt  +downstreamnt
atgcgccacgagaacgtcatcgggctgctggatgtgttcactcctgatgaaaccctggat
gatttcacagacttttacctggtgatgccgttcatggggactgacctgggcaagctcatg
aagcacgagaagctgagtgaggaccgaatccagttcctcgtctaccagatgctgaagggg
ctaaagtatatccatgctgctggcatcatccacagggacctgaagcccggcaatctggcg
gtgaacgaggactgtgagctgaagatcctggactttggcctggcgaggcaggccgacagc
gagatgaccgggtatgtggtgacccggtggtaccgggcacctgaagtcatcttgaattgg
acgcgctacacgcagacagtggacatctggtcggcgggctgcatcatggcagagatgatc
actgggaagacgctgttcaagggcagtgaccacctggaccagctgaaggagatcatgaag
gtgaccgggacgcctcctgctgagtttgttcagaggctgcagagtgccgatgcgaagaac
tacatgaagggcctccccgagctggagaagaaggatttcgcctccatcctgactaatgca
agccctctggccgtgaaccttctggagaaaatgctggtgctggatgcagagcggcgggtg
actgcggccgaggcgctgacccacccctacttcgagtcactacaggacacggaggatgag
cccacggcccagaagtacgacgagtcctttgatgatatggatcacacgctggacgactgg
aaacgtgtcacatataaagaagtgctcagcttcaagcctccccggcagctggggaccaag
gtctccaaggagacggctctgtga

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