Mustela putorius furo (domestic ferret): 101690629
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Entry
101690629 CDS
T07239
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate---cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mpuf
Mustela putorius furo (domestic ferret)
Pathway
mpuf00270
Cysteine and methionine metabolism
mpuf00480
Glutathione metabolism
mpuf01100
Metabolic pathways
mpuf01240
Biosynthesis of cofactors
mpuf04216
Ferroptosis
Module
mpuf_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mpuf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
101690629 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101690629 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
101690629 (GCLC)
Enzymes [BR:
mpuf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
101690629 (GCLC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
HinfI
Motif
Other DBs
NCBI-GeneID:
101690629
NCBI-ProteinID:
XP_004771912
Ensembl:
ENSMPUG00000008858
UniProt:
A0A8U0N8C1
LinkDB
All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVRLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATALLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDEEAAKASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSECGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
RGMFYFRKDICKGGNTMVDGYGKAQHSTEQALEEYALMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIANELCECPELLGPAFRKVKYSGSKTDSST
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagaccaagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtgtcttttgatcat
gaaaataagaaagtccggttggtcctatccggagaggaagttcttgaaactctacaagaa
aagggggaaaggacaaacccaaaccatcctaccctgtggagacctgagtatggcagttac
atgattgaaggcacacccggacagccgtacggaggaacgatgtctgagttcaacaccgtc
gaagacaacatgaggaaacgccggaaggaagcgactgctttattaggagaaaaccaggct
ctctgcacaatcacttcatttcccagattaggctgtcctgggttcacgctgccagagttc
aagcccaatccggttgaaggaggagcttccaagtccctcttctttcctgatgaagccata
aacaagcacccccgctttagtaccctaacaagaaatatccgacacagaagaggagaaaag
gttgtcatcaacgtaccaatatttaaggacaagaatacaccgtctccgtttatagaaaca
tttcctgaggatgaggaggcagccaaggcttctaagcctgatcatatttacatggatgcc
atgggatttggaatgggcaattgctgtcttcaggtaacgttccaagcctgcagcatatcg
gaggccagatacctttatgatcagttggccactatctgtccaattgttatggctttgagt
gcggcatctcctttttaccgaggctatgtgtcagacatcgattgtcgctggggagtgatt
tctgcatctgtggatgacagaactcgggaggagagaggactggagccactgaagaacaat
aactataggatcagtaagtcccgatatgattcgatagacagctacttatctgagtgtggg
gagaaatacaatgacatcgacttgacaatagataaagaaatctatgagcagctgctgcag
gaaggcattgatcatctcctggcccagcatgtcgctcatctcttcattagagacccactg
actctgttcgaagagaaaatacacttggatgatgccaatgaatctgaccattttgagaat
attcagtctacaaattggcagacaatgagatttaagccccctcctccaaactcagatatt
ggatggagagtagaattccgacccatggaggttcagttaacagactttgagaactctgca
tatgtggtgtttgtggtgctgcttaccagagtgatcctttcatacaaactggattttctc
attccactatcaaaggttgacgaaaacatgaaagttgcacagaaacgagacgctgtcttg
cggggaatgttttatttcaggaaagatatttgcaaaggtggcaacaccatggtggacggc
tacggcaaggcccagcacagcacggagcaggcgcttgaggagtacgccctgatgagcata
gacaccatcatcaatgggaaggaaggtgtgtttcccgggctgatcccgattctgaactct
taccttgaaaacatggaagtggatgtggacaccagatgcagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgacagttgccaggtggatgagagagttt
attgcaaaccatcctgactacaagcaagacagtgtcataactgacgaaatgaactacagc
cttattttaaagtgtaaccagattgcaaatgaattatgtgaatgcccagagttacttgga
ccagcatttaggaaagtaaaatatagtggaagtaaaactgactcttccacctag
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