Mycobacterium tuberculosis H37Ra: MRA_0154
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Entry
MRA_0154 CDS
T00540
Name
(GenBank) putative aldehyde dehydrogenase (NAD+) dependent
KO
K00128
aldehyde dehydrogenase (NAD+) [EC:
1.2.1.3
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00010
Glycolysis / Gluconeogenesis
mra00053
Ascorbate and aldarate metabolism
mra00071
Fatty acid degradation
mra00280
Valine, leucine and isoleucine degradation
mra00310
Lysine degradation
mra00330
Arginine and proline metabolism
mra00340
Histidine metabolism
mra00380
Tryptophan metabolism
mra00410
beta-Alanine metabolism
mra00561
Glycerolipid metabolism
mra00620
Pyruvate metabolism
mra00625
Chloroalkane and chloroalkene degradation
mra00770
Pantothenate and CoA biosynthesis
mra00903
Limonene degradation
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01120
Microbial metabolism in diverse environments
mra01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MRA_0154
00053 Ascorbate and aldarate metabolism
MRA_0154
00620 Pyruvate metabolism
MRA_0154
09103 Lipid metabolism
00071 Fatty acid degradation
MRA_0154
00561 Glycerolipid metabolism
MRA_0154
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MRA_0154
00310 Lysine degradation
MRA_0154
00330 Arginine and proline metabolism
MRA_0154
00340 Histidine metabolism
MRA_0154
00380 Tryptophan metabolism
MRA_0154
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
MRA_0154
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
MRA_0154
09109 Metabolism of terpenoids and polyketides
00903 Limonene degradation
MRA_0154
09111 Xenobiotics biodegradation and metabolism
00625 Chloroalkane and chloroalkene degradation
MRA_0154
Enzymes [BR:
mra01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.3 aldehyde dehydrogenase (NAD+)
MRA_0154
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
DRTGG
Motif
Other DBs
NCBI-ProteinID:
ABQ71872
UniProt:
A5TYM2
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All DBs
Position
174597..176117
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AA seq
506 aa
AA seq
DB search
MSDRVKAVAPPDGRTMMTTESVARKTQKSETEAPREPAPVSDEKQTDVAKTVARLRKTFA
SGRTRSVEWRKQQLRALQKLMDENEDAIAAALAEDLDRNPFEAYLADIATTSAEAKYAAK
RVRRWMRRRYLLLEVPQLPGRGWVEYEPYGTVLIIGAWNYPFYLTLGPAVGAIAAGNAVV
LKPSEIAAASAHLMTELVYRYLDTEAIAVVQGDGAVSQELIAQGFDRVMFTGGTEIGRKV
YEGAAPHLTPVTLELGGKSPVIVAADADVDVAAKRIAWIKLLNAGQTCVAPDYVLADATV
RDELVSKITAALTKFRSGAPQGMRIVNQRQFDRLSGYLAAAKTDAAADGGGVVVGGDCDA
SNLRIQPTVVVDPDPDGPLMSNEIFGPILPVVTVKSLDDAIRFVNSRPKPLSAYLFTKSR
AVRERVIREVPAGGMMVNHLAFQVSTAKLPFGGVGASGMGAYHGRWGFEEFSHRKSVLTK
PTRPDLSSFIYPPYTERAIKVARRLF
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
atgagtgaccgcgtcaaggcggtcgcgccgccggacggaaggacgatgatgaccaccgaa
tcggttgcccggaagacccagaaatctgagaccgaggctccgcgcgaaccggcgcccgtt
tcggatgaaaagcaaaccgatgtcgctaaaacggtggctcggctgcgaaagacctttgcc
agcgggcgtacccgcagcgtcgagtggcgcaagcagcagttgcgcgcgctacagaagttg
atggacgagaacgaggacgcgatcgccgcggcactcgccgaggatctggatcgcaatccg
ttcgaggcatacctcgctgacatcgcgacgacctccgccgaagcgaaatacgcggccaag
cgggtgcgcaggtggatgcggcgccgctacctgctgctcgaggtgccgcagctgcccggc
cgcggctgggtggagtacgagccatatggcaccgtgctaatcatcggtgcctggaactac
ccgttctacctgaccctgggtccggcggtcggagccattgccgctggaaacgccgtcgtg
ctcaaaccgtcggaaatcgccgctgcatcggcgcacttgatgaccgaattggtgtatcgc
tatctcgacaccgaagcgatcgcggtcgtgcagggcgatggtgcggtgagtcaggagctg
atcgctcagggtttcgaccgcgtgatgttcaccggtggcaccgagatcggccgcaaggtc
tacgaaggcgccgcgccgcacctgaccccggtcaccctcgagctcggcggcaagagcccg
gtgatcgtcgcggccgatgccgatgtagatgtcgcggccaagcggatcgcctggatcaaa
ctgctcaacgccgggcagacatgcgttgcacccgactatgtgctggcggatgccaccgtc
cgcgacgagctggtcagcaagatcaccgcggccctcaccaagttccgctccggtgcgccg
cagggcatgcgcatcgtcaaccagcgtcaattcgaccggctgagtggatacctcgccgca
gcgaaaaccgacgctgcagccgacggcggcggggtcgtcgtgggcggcgactgtgacgca
tcgaacctgcgcatccaacccaccgtggtcgtcgatcccgacccggacgggccgttgatg
agcaacgagatcttcggaccgatcctgccggtggtcaccgtcaaatctctggacgacgcg
attcgcttcgtgaactcgcggcccaagccgctatcggcgtacctgttcactaagtcgcgt
gcggttcgcgagcgggtgatcagggaggtgccggcgggcggaatgatggttaaccatttg
gcttttcaggtgtcgacggccaaactgccgttcggtggtgtcggcgcatcgggcatgggt
gcctaccacggccgttggggtttcgaggagttcagccaccgtaagtcggtgttgaccaaa
ccaacccgacccgacctgtccagctttatctacccgccgtacaccgagcgcgccatcaag
gtggctcgccggctgttctga
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