Mycobacterium tuberculosis H37Ra: MRA_0777
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Entry
MRA_0777 CDS
T00540
Symbol
aldA
Name
(GenBank) NAD-dependent aldehyde dehydrogenase AldA
KO
K00128
aldehyde dehydrogenase (NAD+) [EC:
1.2.1.3
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00010
Glycolysis / Gluconeogenesis
mra00053
Ascorbate and aldarate metabolism
mra00071
Fatty acid degradation
mra00280
Valine, leucine and isoleucine degradation
mra00310
Lysine degradation
mra00330
Arginine and proline metabolism
mra00340
Histidine metabolism
mra00380
Tryptophan metabolism
mra00410
beta-Alanine metabolism
mra00561
Glycerolipid metabolism
mra00620
Pyruvate metabolism
mra00625
Chloroalkane and chloroalkene degradation
mra00770
Pantothenate and CoA biosynthesis
mra00903
Limonene degradation
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01120
Microbial metabolism in diverse environments
mra01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MRA_0777 (aldA)
00053 Ascorbate and aldarate metabolism
MRA_0777 (aldA)
00620 Pyruvate metabolism
MRA_0777 (aldA)
09103 Lipid metabolism
00071 Fatty acid degradation
MRA_0777 (aldA)
00561 Glycerolipid metabolism
MRA_0777 (aldA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MRA_0777 (aldA)
00310 Lysine degradation
MRA_0777 (aldA)
00330 Arginine and proline metabolism
MRA_0777 (aldA)
00340 Histidine metabolism
MRA_0777 (aldA)
00380 Tryptophan metabolism
MRA_0777 (aldA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
MRA_0777 (aldA)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
MRA_0777 (aldA)
09109 Metabolism of terpenoids and polyketides
00903 Limonene degradation
MRA_0777 (aldA)
09111 Xenobiotics biodegradation and metabolism
00625 Chloroalkane and chloroalkene degradation
MRA_0777 (aldA)
Enzymes [BR:
mra01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.3 aldehyde dehydrogenase (NAD+)
MRA_0777 (aldA)
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
LuxC
Motif
Other DBs
NCBI-ProteinID:
ABQ72506
UniProt:
A5U0F6
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All DBs
Position
862218..863687
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AA seq
489 aa
AA seq
DB search
MALWGDGISALLIDGKLSDGRAGTFPTVNPATEEVLGVAADADAEDMGRAIEAARRAFDS
TDWSRNTELRVRCVRQLRDAMQQHVEELRELTISEVGAPRMLTASAQLEGPVGDLSFAAD
TAESYPWKQDLGEASPLGIATRRTLAREAVGVVGAITPWNFPHQINLAKLGPALAAGNTV
VLKPAPDTPWCAAALGEIIVEHTDFPPGVVNIVTSSSHALGALLAKDPRVDMISFTGSTA
TGRAVMADAAATIKKVFLELGGKSAFVVLDDADLAAASAVSAFSACMHAGQGCAITTRLV
VPRARYEEAVAIAAATMSSIRPGDPNDPGTVCGPLISARQRDRVQGYLDLAVAEGGRFAC
GGARPADREVGFYIEPTVIAGLTNDARVAREEIFGPVLTVIAHDGDDDAVRIANDSPYGL
SGTVYGADPQRAARIASRLRVGTVNVNGGVWYCADAPFGGYKQSGIGREMGLLGFEEYLE
AKLIATAAN
NT seq
1470 nt
NT seq
+upstream
nt +downstream
nt
atggccctgtggggcgacggaattagtgcgctgctcatcgacggcaaactatcggacggc
cgtgcgggcaccttcccgacggtcaatccggccaccgaggaagtgctgggagtcgccgcc
gacgccgatgccgaggacatgggccgcgccatcgaggccgcgcggcgggcgttcgactcg
accgactggtcccgcaataccgaacttcgggtgcggtgtgttcggcaactgcgcgacgca
atgcaacagcacgtcgaagaactacgcgaactgacgatctccgaggtgggcgcgccgcgg
atgctcaccgccagcgcccagctggaaggcccggtcggggatctatcgtttgcggcggac
acggccgagtcctacccgtggaagcaggacctcggcgaggcatcgccgttgggcatcgcc
acccggcgcaccctcgcacgggaggccgtcggtgtcgtcggcgccatcaccccgtggaac
ttcccgcaccagatcaatctcgccaagctaggtccggcgctagccgcgggtaacaccgtc
gttttaaagccggcgcctgacacaccgtggtgcgcagcagcgctcggggaaatcatcgtc
gagcacaccgacttcccaccgggcgttgtcaacatcgtcacctccagcagtcacgctttg
ggggcgctgttggccaaagaccctcgggtggacatgatttcgttcaccggttctactgcg
accggccgtgccgtaatggccgatgccgcggccaccatcaaaaaggtttttctggaactg
ggtggcaagtcggcgttcgtcgtgctcgacgacgctgacctagccgctgccagcgcggta
tcggcgttctcggcttgcatgcacgccgggcaggggtgcgcaatcacgacccggctggtg
gtgccacgggcccgttatgaagaggcggttgccatcgcggcagccaccatgtcgtcgatc
aggcccggcgatcccaacgaccccggaaccgtttgcgggccgttgatttcggcccgacaa
cgggatcgtgtgcagggctacctcgacctggcggtcgccgaaggcggaaggttcgcatgc
ggtggcgcgcggccggcggatagagaggtcggtttctacatcgagcccacggtcatcgca
gggttgaccaatgacgccagagtcgcccgagaggagatcttcggaccggtgctcacggtg
attgcccacgacggtgacgatgatgcggtgcgcatcgccaacgactcgccatacggcttg
tcgggcaccgtgtatggcgccgacccgcagcgcgccgcgaggattgcctcgcggctgcgg
gtaggcaccgtcaacgtcaatgggggtgtctggtactgcgccgacgcgccgttcggcggc
tacaagcaatccggtatcggacgcgagatgggtctcctcggcttcgaggagtacttagaa
gccaaactcattgctaccgctgcaaattag
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