Mycobacterium tuberculosis H37Ra: MRA_0786
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Entry
MRA_0786 CDS
T00540
Symbol
purB
Name
(GenBank) adenylosuccinate lyase
KO
K01756
adenylosuccinate lyase [EC:
4.3.2.2
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00230
Purine metabolism
mra00250
Alanine, aspartate and glutamate metabolism
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01232
Nucleotide metabolism
mra01240
Biosynthesis of cofactors
Module
mra_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
mra_M00049
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MRA_0786 (purB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
MRA_0786 (purB)
Enzymes [BR:
mra01000
]
4. Lyases
4.3 Carbon-nitrogen lyases
4.3.2 Amidine-lyases
4.3.2.2 adenylosuccinate lyase
MRA_0786 (purB)
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GFIT
Motif
Pfam:
Lyase_1
ADSL_C
Motif
Other DBs
NCBI-ProteinID:
ABQ72515
UniProt:
A5U0G5
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Position
871314..872732
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AA seq
472 aa
AA seq
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MSIPNVLATRYASAEMVAIWSPEAKVVSERRLWLAVLRAQAELGVAVADSVLADYERVVD
DVDLASISARERVLRHDVKARIEEFNALAGHEHVHKGMTSRDLTENVEQLQIRRSLEVIF
AHGVAAVARLAERAVSYRDLIMAGRSHNVAAQATTLGKRFASAAQEMMIALRRLRELIDR
YPLRGIKGPMGTGQDMLDLLGGDRAALADLERRVADFLGFATVFNSVGQVYPRSLDHDVV
SALVQLGAGPSSLAHTIRLMAGHELATEGFAPGQVGSSAMPHKMNTRSCERVNGLQVVLR
GYASMVAELAGAQWNEGDVFCSVVRRVALPDSFFAVDGQIETFLTVLDEFGAYPAVIGRE
LDRYLPFLATTKVLMAAVRAGMGRESAHRLISEHAVATALAMREHGAEPDLLDRLAADPR
LTLGRDALEAALADKKAFAGAAGDQVDDVVAMVDALVSRYPDAAKYTPGAIL
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
gtgagcattcccaacgtgctggccacccgatacgccagcgccgagatggtcgcgatctgg
tcgccggaggccaaggtggtctcggagcggcggttatggctggccgtattgcgggcacag
gcagagctgggggtagcggttgccgattcggtgctcgccgactacgaacgtgtggtcgac
gatgtggacttggcctcgatctcagcccgggagcgggtgctgcgccacgatgtcaaggcc
cgcatcgaggaattcaacgcattggccggtcatgagcacgtgcacaaggggatgaccagc
cgcgacctgaccgagaacgtggagcaactgcagattcggcggtcgctggaagtgattttc
gcccatggggtggcggcggtggcgcggctggccgagcgggcggtgagctaccgtgacctg
atcatggccgggcgcagccacaacgtggccgctcaggccaccaccttgggcaagcggttc
gcctcggcggcccaagagatgatgatcgcgttgaggcggttgagggagttgatcgaccgc
taccccctgcgtggcatcaagggcccgatgggcaccggtcaggacatgctcgatctgctg
ggcggtgaccgtgcggcgctggccgatctcgagcggcgcgtcgccgacttcttgggcttt
gcaactgttttcaacagcgtggggcaggtgtatccgcgttcattggaccacgacgtggtt
tcggctctggtgcagctcggcgcggggccgtcatcactggcacacacgattcgattgatg
gccggccacgagctcgccaccgagggtttcgcgccgggtcaggtcggttcgtcggcgatg
ccgcacaagatgaacacccgcagctgcgaacgggtcaacgggctgcaggttgtgctacgc
ggctatgcatccatggtggccgagttagccggtgcacagtggaacgagggtgatgtgttt
tgctccgtggtgcgccgggttgcgttgccggacagcttctttgccgtcgacgggcagatc
gagacgtttttgacggtgctggacgagttcggcgcctacccggcggtgatcggccgcgag
ttggatcgttatctgccgttcctggccaccactaaggtgctaatggcggccgtgcgcgcg
gggatgggtcgcgagtccgcgcaccggttgatctccgagcacgcggtggcgacggcgctg
gccatgcgagaacacggcgcggagcccgacctgctggaccggttggccgccgatccgcgg
ctgacgctgggacgagacgctttggaggccgcgctggccgacaagaaggcatttgccggt
gccgcgggtgaccaggtcgatgatgtggtcgcgatggtggacgcgctggtgagccgttac
ccggacgcggctaaatacacgccgggtgcaattctttag
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