Mycobacterium tuberculosis H37Ra: MRA_0813
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Entry
MRA_0813 CDS
T00540
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase subunit II
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00230
Purine metabolism
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
Module
mra_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MRA_0813 (purL)
Enzymes [BR:
mra01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MRA_0813 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
FGAR-AT_PurM_N-like
Motif
Other DBs
NCBI-ProteinID:
ABQ72542
UniProt:
A5U0J2
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Position
897126..899390
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AA seq
754 aa
AA seq
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MLDTVEHAATTPDQPQPYGELGLKDDEYRRIRQILGRRPTDTELAMYSVMWSEHCSYKSS
KVHLRYFGETTSDEMRAAMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATG
VGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNSLGLPNIGGETV
FDPCYAGNPLVNALCVGVLRQEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASDTFD
AEGSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVIGIQDLGGAGLSCATSELASAGDGG
MTIQLDSVPLRAKEMTPAEVLCSESQERMCAVVSPKNVDAFLAVCRKWEVLATVIGEVTD
GDRLQITWHGETVVDVPPRTVAHEGPVYQRPVARPDTQDALNADRSAKLSRPVTGDELRA
TLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGMLRIDESTGRGIAVSTDASGRY
TLLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPGVMWQFTQAVRGLADGCA
DLGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVIDDVRRRIPTGLGAEPGETLMLLGDTR
DEFDGSVWAQVTADHLGGLPPVVDLAREKLLAAVLSSASRDGLVSAAHDLSEGGLAQAIV
ESALAGETGCRIVLPEGADPFVLLFSESAGRVLVAVPRTEESRFRGMCEARGLPAVRIGV
VDQGSDAVEVQGLFAVSLAELRATSEAVLPRYFG
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
gtgctggacaccgtcgaacacgccgcgaccacacccgaccaaccacaaccgtatggtgag
ctgggcctcaaagacgacgagtaccggcggattcgccagatcctgggccgccggcccacc
gacaccgagctggccatgtactcggtgatgtggagcgaacactgttcgtacaagtcctcc
aaggtgcacctgcgctacttcggtgagaccacctccgacgagatgcgcgcggccatgctg
gccggcatcggcgagaacgccggcgtcgtcgacatcggcgacggctgggcggtcaccttc
aaggtggagtcacacaaccacccgtcctacgtcgagccctaccagggcgcggccaccggg
gtgggcggcatcgtccgcgacatcatggccatgggcgcccgaccggtcgccgtgatggac
cagcttcggttcggcgccgccgacgcccccgatacccgccgcgtgctcgacggcgtggtc
cgcggcatcggcggatacggcaactccctgggcctgcccaacattggcggagagaccgtc
ttcgacccgtgctacgccggcaaccccttagtgaacgcgttgtgtgtcggcgtattacgg
caggaggacctgcatttggcgttcgcctccggcgccggcaacaagatcatcctgtttggc
gcgcgcaccgggctcgacggtatcggcggggtgtcggtgctggcgtcggacaccttcgat
gccgagggatcccgcaagaagctgccctcggtgcaggtcggcgacccgttcatggagaag
gtgctcatcgaatgctgtctcgagctctacgcgggcggcctggtgatcggcatccaagac
ctgggcggagccggattatcttgtgccacatcggagttagcatccgccggtgatggcgga
atgacgatccagctggacagcgtcccgctgcgggccaaggagatgacgcccgccgaggtg
ctctgcagcgaatcgcaggagcggatgtgcgcggtggtctccccgaagaacgtcgacgca
ttcctggcggtgtgccgcaagtgggaggtgctggcgacggtgatcggcgaggtcaccgac
ggcgaccggctgcagatcacctggcacggcgagacggtggtcgacgtgccgccgcgcacc
gtagctcacgaaggtccggtatatcagcgcccggtcgcccgccccgatacgcaggacgcg
ctgaacgccgaccgctcggccaagctgtcacggccggtcaccggcgacgagctgcgcgcg
actttgcttgcgttacttggcagcccgcacctgtgcagccgcgcgttcatcaccgagcag
tacgaccgctatgtgcgcggcaacacggtgctcgccgagcacgccgacggcggcatgctg
cgcatcgacgagtcgaccggccggggcatcgcggtatcgaccgacgcgtcgggacgctac
acgctgctggatccctacgctggcgcgcaactcgcgttggccgaggcgtaccgcaacgtc
gccgtcaccggcgccaccccggtcgcggtgaccaactgcctgaacttcggttcccccgag
gaccccggcgtgatgtggcagttcacgcaggcggtccgcggtctggccgatggctgtgcg
gacctcgggattccggtgaccggtggcaacgtgagtttctacaaccaaaccggttcggcg
gcaatcctgcccacgccggtggtcggggtgctcggcgtcatcgacgatgtgcgtcggcgc
atccctaccggcctgggcgccgagcccggggaaacgttgatgctgttgggcgacacccgc
gacgagttcgacggttccgtgtgggcgcaggtgaccgcagaccacctgggtggattgccg
ccggtagtcgatctggcgcgggagaagctgctggccgcggtgctgagctcggcgtcgcgg
gacgggctagtgtccgcggcgcacgatctgtccgagggtgggctggcccaagccatcgtg
gaatcggcgttagcgggtgaaaccggttgccgcatagtgcttcccgaaggggctgacccg
tttgtgctgctgttctccgagtcggcgggtcgggtgctggtcgcggtgccacgcaccgag
gagagccggtttcgcgggatgtgtgaggcgcggggacttcccgcggtccgcatcggcgtc
gtcgatcaaggttcggacgcggttgaggtgcagggcttgttcgcggtgtcgttggccgaa
ctgcgtgcgacatccgaggcggtgttgccgcgatacttcggatga
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