Mycobacterium tuberculosis H37Ra: MRA_0868
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Entry
MRA_0868 CDS
T00540
Symbol
fadB
Name
(GenBank) fatty oxidation complex subunit alpha
KO
K01782
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00071
Fatty acid degradation
mra00280
Valine, leucine and isoleucine degradation
mra00310
Lysine degradation
mra00362
Benzoate degradation
mra00380
Tryptophan metabolism
mra00410
beta-Alanine metabolism
mra00640
Propanoate metabolism
mra00650
Butanoate metabolism
mra00907
Pinene, camphor and geraniol degradation
mra00930
Caprolactam degradation
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01120
Microbial metabolism in diverse environments
mra01200
Carbon metabolism
mra01212
Fatty acid metabolism
Module
mra_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MRA_0868 (fadB)
00650 Butanoate metabolism
MRA_0868 (fadB)
09103 Lipid metabolism
00071 Fatty acid degradation
MRA_0868 (fadB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MRA_0868 (fadB)
00310 Lysine degradation
MRA_0868 (fadB)
00380 Tryptophan metabolism
MRA_0868 (fadB)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
MRA_0868 (fadB)
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
MRA_0868 (fadB)
09111 Xenobiotics biodegradation and metabolism
00362 Benzoate degradation
MRA_0868 (fadB)
00930 Caprolactam degradation
MRA_0868 (fadB)
Enzymes [BR:
mra01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
MRA_0868 (fadB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
MRA_0868 (fadB)
5. Isomerases
5.1 Racemases and epimerases
5.1.2 Acting on hydroxy acids and derivatives
5.1.2.3 3-hydroxybutyryl-CoA epimerase
MRA_0868 (fadB)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
ECH_2
3HCDH
NAD_binding_2
F420_oxidored
DAO
Motif
Other DBs
NCBI-ProteinID:
ABQ72598
UniProt:
A5U0P8
LinkDB
All DBs
Position
957599..959761
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AA seq
720 aa
AA seq
DB search
MPDNTIQWDKDADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASA
KKTFFAGGDVKTMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEI
ALACHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAK
AKEIGLVDELVATVEELVPAAKAWIKEELKANPDGAGVQPWDKKGYKMPGGTPSSPGLAA
ILPSFPSNLRKQLKGAPMPAPRAILAAAVEGAQVDFDTASRIESRYFASLVTGQVAKNMM
QAFFFDLQAINAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEA
AAKGKGYSEKLEAKALERGRTTQERSDALLARITPTADAADFKGVDFVIEAVFENQELKH
KVFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEK
TSDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGS
QAGYPAPPLQLSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRSGRLK
GAGFYEYADGKRSGLWPGLRETFKSGSSQPPLQDMIDRMLFAEALETQKCLDEGVLTSTA
DANIGSIMGIGFPPWTGGSAQFIVGYSGPAGTGKAAFVARARELAAAYGDRFLPPESLLS
NT seq
2163 nt
NT seq
+upstream
nt +downstream
nt
atgccagacaacacaatccagtgggacaaggatgccgacggcatcgtcacgctgaccatg
gacgatccctccgggtcaaccaacgtgatgaacgaggcctacatcgagtcgatgggcaag
gccgtcgatcgccttgtcgccgaaaaggattcgatcaccggagtggtagtcgccagcgcg
aagaaaaccttcttcgccggcggcgacgtcaagacgatgatccaggccaggcccgaggac
gccggcgatgtattcaacaccgtcgagaccatcaagcggcagctgcgcaccttggagaca
ttgggtaagccggtcgtcgcggccatcaacggggcggcgttgggcggcggcctggagatc
gcgctggcgtgtcatcaccggatcgccgccgacgtcaagggcagccagctcggtctgccg
gaggtgacgctgggtctgctgccgggtggcggtggggtgacccgcacggtacggatgttc
ggcatccagaacgcgttcgtgagcgtgctggcgcaaggtacccggttcaagccggccaag
gccaaggagatcggtctggtcgacgagctggtggcaacggtcgaggagctggtgcccgcc
gccaaggcttggataaaggaggagctcaaggccaaccccgacggtgccggggtgcagccg
tgggacaagaagggctacaagatgcccggcggcaccccgtcgtcgccgggtctggcggcg
attttgccgtcgttcccgtcgaacctgcgcaagcagctcaagggtgccccgatgccggcg
ccgcgggccatcctggccgccgcggtcgagggggcacaggtcgatttcgacaccgccagc
cgcatcgagagccgctacttcgcgtcgttggtcaccggccaggtcgccaagaacatgatg
caggcgttcttcttcgacctgcaggccatcaatgccggcgggtctcggcccgaaggcatc
ggcaagaccccgatcaagaggatcggtgtgctgggtgcgggcatgatgggcgccggcatc
gcctacgtctctgccaaggccggctatgaggtggtactcaaagatgtcagccttgaggcc
gccgctaaaggcaagggctactccgaaaagctggaggccaaggcgctggagcggggccgc
accacacaggagcgcagcgacgccctgctggcgcgcatcaccccgaccgccgacgccgcc
gatttcaagggcgttgatttcgtgatcgaggcggtttttgaaaaccaggagctcaagcac
aaggtgttcggcgagatcgaagacatcgtcgagcccaacgcgatcctgggatccaacacc
tcgacgctgccgatcaccggtctggcgaccggcgtcaagcggcaggaagactttatcggg
atccacttcttctcgccggtcgacaagatgccgctggtggagatcatcaagggcgagaag
acttctgacgaggccctggcccgggtgttcgactacaccttggccatcggcaagaccccg
atcgtggtcaacgacagccgcggctttttcacctcgcgggtcatcggcacgttcgtcaac
gaggcgctggcgatgctcggtgagggtgtcgagccggcttctatcgagcaggcggggtcg
caggccgggtatccggcgccgccgctgcagctgtccgacgagctcaacttggagctgatg
cacaagatcgccgtcgccacccgtaagggtgttgaggacgccggcggcacgtaccagccg
catccggcggaggccgtggtggagaagatgatcgagctcggccggtccggccggctgaag
ggcgcgggcttctacgagtacgccgacggcaagcgatccgggttgtggcccggcttgcgc
gagacgttcaagtcgggctcgtcgcagccgccgctgcaggacatgatcgaccgcatgctg
ttcgccgaggcgctggaaacccagaagtgcctcgacgagggggtgctgacgtcgacggcc
gacgccaacatcggctcgatcatgggcatcggcttcccgccgtggacaggtggcagtgcc
cagttcatcgtcggctactccggcccggccggtaccggtaaggcggctttcgtggcccgg
gcccgcgagctggcggccgcctacggcgaccgcttcctgccgccggagtcgctgctaagc
tga
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