Mycobacterium tuberculosis H37Ra: MRA_1613
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Entry
MRA_1613 CDS
T00540
Symbol
hisA
Name
(GenBank) phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
KO
K24017
phosphoribosyl isomerase A [EC:
5.3.1.16
5.3.1.24
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00340
Histidine metabolism
mra00400
Phenylalanine, tyrosine and tryptophan biosynthesis
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01230
Biosynthesis of amino acids
Module
mra_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
MRA_1613 (hisA)
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
MRA_1613 (hisA)
Enzymes [BR:
mra01000
]
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.1 Interconverting aldoses and ketoses, and related compounds
5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
MRA_1613 (hisA)
5.3.1.24 phosphoribosylanthranilate isomerase
MRA_1613 (hisA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
His_biosynth
NMO
Dus
Motif
Other DBs
NCBI-ProteinID:
ABQ73359
UniProt:
A5U2V9
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Position
1804812..1805549
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AA seq
245 aa
AA seq
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MMPLILLPAVDVVEGRAVRLVQGKAGSQTEYGSAVDAALGWQRDGAEWIHLVDLDAAFGR
GSNHELLAEVVGKLDVQVELSGGIRDDESLAAALATGCARVNVGTAALENPQWCARVIGE
HGDQVAVGLDVQIIDGEHRLRGRGWETDGGDLWDVLERLDSEGCSRFVVTDITKDGTLGG
PNLDLLAGVADRTDAPVIASGGVSSLDDLRAIATLTHRGVEGAIVGKALYARRFTLPQAL
AAVRD
NT seq
738 nt
NT seq
+upstream
nt +downstream
nt
gtgatgccgctgatacttttgcccgccgtcgacgtggtcgagggtcgtgccgtgcgcctc
gttcaagggaaggccggcagccaaaccgagtacggctcagcggtggatgccgcgttgggc
tggcaacgcgatggcgccgagtggatccatttggtggacctggatgctgcgttcggccgc
ggttccaaccacgaactgcttgccgaggttgtcggcaagctcgacgtacaggttgagcta
tccggcggtattcgagacgacgagtcgctggccgcggcgctggccaccggatgcgctcgg
gtcaatgtgggcactgctgccctggaaaacccgcagtggtgtgcccgggtgattggcgag
cacggcgaccaggtcgccgtcggcttggacgtccagatcatcgacggcgagcatcggttg
cgcggacgcggctgggaaaccgacggcggcgacctgtgggacgtgctagaacgcctagac
agtgaaggatgttcgcggttcgtcgtgaccgatatcaccaaggacggcaccctgggcggc
cccaatctggacctgctggccggtgttgccgaccgcaccgacgccccggtgatcgcgtcc
ggaggtgtgtccagcctcgatgacctgcgcgccattgcgactctcacgcaccgcggcgtc
gagggggccatcgtcggcaaggccctctacgcccgtcggttcaccttgccgcaagcgttg
gccgcggttcgggactag
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