Mycobacterium tuberculosis H37Ra: MRA_1741
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Entry
MRA_1741 CDS
T00540
Symbol
gabD2
Name
(GenBank) succinic semialdehyde dehydrogenase
KO
K00135
succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:
1.2.1.16
1.2.1.79
1.2.1.20
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00250
Alanine, aspartate and glutamate metabolism
mra00310
Lysine degradation
mra00350
Tyrosine metabolism
mra00650
Butanoate metabolism
mra00760
Nicotinate and nicotinamide metabolism
mra01100
Metabolic pathways
mra01120
Microbial metabolism in diverse environments
Module
mra_M00027
GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
MRA_1741 (gabD2)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
MRA_1741 (gabD2)
00310 Lysine degradation
MRA_1741 (gabD2)
00350 Tyrosine metabolism
MRA_1741 (gabD2)
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
MRA_1741 (gabD2)
Enzymes [BR:
mra01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
MRA_1741 (gabD2)
1.2.1.20 glutarate-semialdehyde dehydrogenase
MRA_1741 (gabD2)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
MRA_1741 (gabD2)
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Motif
Pfam:
Aldedh
LuxC
Motif
Other DBs
NCBI-ProteinID:
ABQ73490
UniProt:
A5U390
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All DBs
Position
1959195..1960751
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AA seq
518 aa
AA seq
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MPAPSAEVFDRLRNLAAIKDVAARPTRTIDEVFTGKPLTTIPVGTAADVEAAFAEARAAQ
TDWAKRPVIERAAVIRRYRDLVIENREFLMDLLQAEAGKARWAAQEEIVDLIANANYYAR
VCVDLLKPRKAQPLLPGIGKTTVCYQPKGVVGVISPWNYPMTLTVSDSVPALVAGNAVVL
KPDSQTPYCALACAELLYRAGLPRALYAIVPGPGSVVGTAITDNCDYLMFTGSSATGSRL
AEHAGRRLIGFSAELGGKNPMIVARGANLDKVAKAATRACFSNAGQLCISIERIYVEKDI
AEEFTRKFGDAVRNMKLGTAYDFSVDMGSLISEAQLKTVSGHVDDATAKGAKVIAGGKAR
PDIGPLFYEPTVLTNVAPEMECAANETFGPVVSIYPVADVDEAVEKANDTDYGLNASVWA
GSTAEGQRIAARLRSGTVNVDEGYAFAWGSLSAPMGGMGLSGVGRRHGPEGLLKYTESQT
IATARVFNLDPPFGIPATVWQKSLLPIVRTVMKLPGRR
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgcctgcaccctcggccgaggttttcgatcgcttgcgtaacctggccgcgatcaaggac
gtcgccgcacgtccgaccaggacgatcgacgaggtcttcaccggcaagccgttgactacg
attccggtcggcacggccgcggacgtcgaagcggcattcgccgaagctcgcgcggcgcag
accgactgggcgaagcgtcccgtcatcgagcgagctgcagtcatccgccgctatcgcgac
ctggtcatcgagaaccgcgagttcctcatggacctcctgcaagccgaggcgggcaaggcc
cgatgggcggcgcaagaggaaattgtcgatctgatcgcgaacgcgaattattacgcacga
gtctgtgtggacctgctgaagccccgtaaggcacagccgctgctgcccgggataggcaag
accacggtgtgctatcaaccgaagggcgtggtgggggtgatctcgccgtggaactacccc
atgacgcttacggtgtcggactcggtgcccgcgctggtggccggtaacgcggtggtgctc
aagccggacagccagacgccgtattgtgcgctcgcgtgtgccgagctgctgtatcgggcg
ggtctgccgcgagcgctgtatgcgatcgtgcccggtccgggctcggtggtgggcaccgcc
atcaccgacaactgcgactacctgatgttcaccggttcatcggcgaccggcagccgcctc
gccgagcacgccggccgccggcttatcggtttctcggccgaacttggcggcaagaacccc
atgatcgtggcgcggggtgccaacctcgacaaggtcgccaaggcggccacccgtgcctgc
ttctcgaacgccggccagctgtgcatctccattgagcggatctacgtcgaaaaggacatc
gccgaggagttcacccggaagttcggcgatgcggtgcggaacatgaagctcggcaccgca
tacgacttctcggtcgacatgggtagtttgatctccgaagcacagctgaaaaccgtgtcc
ggtcacgtggatgacgcgacggccaagggcgccaaggtgattgcgggcggcaaggctcga
cccgacatcgggccgctgttctacgagccgaccgtgctgaccaacgtcgcacccgaaatg
gaatgcgcggccaacgagacgttcgggccggtggtctcgatctacccggtcgccgacgtg
gacgaagccgtcgaaaaggccaacgacaccgactacgggctcaacgccagcgtctgggcc
ggctccaccgcggagggccagaggatcgccgcccggctgcggtcggggacggtgaacgtc
gacgaggggtacgcgttcgcctggggcagcctcagcgcgccgatgggcgggatgggcctc
tcgggggtcggccgccggcacggtccggagggcttgctcaagtacaccgaatcacagacg
atcgcgaccgcccgcgtgttcaatctcgatccgcccttcggcatcccggccacagtctgg
cagaagtcactgttacccatcgtgcgcaccgtgatgaagcttcccggccgcaggtga
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