Mycobacterium tuberculosis H37Ra: MRA_1843
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Entry
MRA_1843 CDS
T00540
Symbol
gcvB
Name
(GenBank) glycine dehydrogenase
KO
K00281
glycine cleavage system P protein (glycine dehydrogenase) [EC:
1.4.4.2
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00260
Glycine, serine and threonine metabolism
mra00630
Glyoxylate and dicarboxylate metabolism
mra00670
One carbon pool by folate
mra00785
Lipoic acid metabolism
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01200
Carbon metabolism
Module
mra_M00621
Glycine cleavage system
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
MRA_1843 (gcvB)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MRA_1843 (gcvB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MRA_1843 (gcvB)
00670 One carbon pool by folate
MRA_1843 (gcvB)
Enzymes [BR:
mra01000
]
1. Oxidoreductases
1.4 Acting on the CH-NH2 group of donors
1.4.4 With a disulfide as acceptor
1.4.4.2 glycine dehydrogenase (aminomethyl-transferring)
MRA_1843 (gcvB)
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GFIT
Motif
Pfam:
GDC-P
GcvP2_C
Aminotran_5
Beta_elim_lyase
Aminotran_1_2
SepSecS
Motif
Other DBs
NCBI-ProteinID:
ABQ73599
UniProt:
A5U3J9
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All DBs
Position
2085809..2088634
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AA seq
941 aa
AA seq
DB search
MSDHSTFADRHIGLDSQAVATMLAVIGVDSLDDLAVKAVPAGILDTLTDTGAAPGLDSLP
PAASEAEALAELRALADANTVAVSMIGQGYYDTHTPPVLLRNIIENPAWYTAYTPYQPEI
SQGRLEALLNFQTLVTDLTGLEIANASMLDEGTAAAEAMTLMHRAARGPVKRVVVDADVF
TQTAAVLATRAKPLGIEIVTADLRAGLPDGEFFGVIAQLPGASGRITDWSALVQQAHDRG
ALVAVGADLLALTLIAPPGEIGADVAFGTTQRFGVPMGFGGPHAGYLAVHAKHARQLPGR
LVGVSVDSDGTPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAMYASYHGAGGLTAI
ARRVHAHAEAIAGALGDALVHDKYFDTVLARVPGRADEVLARAKANGINLWRVDADHVSV
ACDEATTDTHVAVVLDAFGVAAAAPAHTDIATRTSEFLTHPAFTQYRTETSMMRYLRALA
DKDIALDRSMIPLGSCTMKLNAAAEMESITWPEFGRQHPFAPASDTAGLRQLVADLQSWL
VLITGYDAVSLQPNAGSQGEYAGLLAIHEYHASRGEPHRDICLIPSSAHGTNAASAALAG
MRVVVVDCHDNGDVDLDDLRAKVGEHAERLSALMITYPSTHGVYEHDIAEICAAVHDAGG
QVYVDGANLNALVGLARPGKFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVRAHLAPFLPG
HPFAPELPKGYPVSSAPYGSASILPITWAYIRMMGAEGLRAASLTAITSANYIARRLDEY
YPVLYTGENGMVAHECILDLRGITKLTGITVDDVAKRLADYGFHAPTMSFPVAGTLMVEP
TESESLAEVDAFCEAMIGIRAEIDKVGAGEWPVDDNPLRGAPHTAQCLLASDWDHPYTRE
QAAYPLGTAFRPKVWPAVRRIDGAYGDRNLVCSCPPVEAFA
NT seq
2826 nt
NT seq
+upstream
nt +downstream
nt
gtgtccgaccattcgacgttcgcagaccggcacatcggtctggacagccaggccgtcgcg
accatgctcgccgtgatcggggtggattcgctcgatgacctggcagtcaaggcggtcccg
gcgggcatcctagacacactcaccgacaccggagccgcaccgggtttggacagtctgcca
ccggctgccagcgaagccgaggcgctggccgagctgcgagcgctggccgacgctaacacc
gtcgccgtgtcgatgatcgggcaaggctactacgacacacacacccccccggtgctgttg
cgcaacatcatcgagaacccggcctggtataccgcctacacgccgtaccagcccgagatt
agtcagggtcggctggaagccttgctgaacttccagaccctggtcaccgatctgaccggc
ctcgagatcgcgaacgcgtcgatgctcgacgagggcaccgcggcggccgaggccatgact
ttgatgcaccgcgcggcccgcgggccggtgaagagggtggtcgtggacgccgacgtgttc
acccagaccgcggcggtgctggccacccgcgccaagccgctgggtatcgagatcgtcacg
gccgacctgcgcgccggtctgcccgacggcgaatttttcggcgtcatcgcccagctgccc
ggggccagcggccggatcaccgactggtctgccctggtgcaacaggcccacgaccgtggc
gcactggtggccgtcggcgccgacttgttggcgctgacgctgatcgcgccgcccggagag
atcggcgctgacgtcgcctttggcaccacacaacggttcggagtgccgatggggtttggc
ggcccgcatgccgggtaccttgcggtgcacgccaagcatgcgcgtcagctgcccggccgg
ctggtcggtgtgtccgtcgacagtgacggcacgccggcctatcggttggcgctgcagact
cgcgagcaacacatccgccgcgacaaggccaccagcaacatctgcaccgcacaagtgctg
ttggcggtgcttgccgcgatgtacgcgagctaccacggcgcgggcgggctgaccgccatc
gcacgccgggtgcatgcccacgccgaggctatcgccggtgcactgggcgatgcgttggtg
cacgacaagtacttcgacacggtgttggcccgggtgcccggtcgtgccgacgaggtgctg
gccagggccaaggccaacggcatcaacctgtggcgtgtcgacgccgaccatgtgtcggta
gcctgcgacgaagccaccactgacacccacgtggcggtcgttctggacgcgttcggtgta
gcggccgccgcacccgcccatacggacatcgcaacgcgcacatcggagttcctgacgcat
ccagcgttcacgcaataccgcaccgagacgtcgatgatgcggtacttgcgtgcgctggcg
gataaggatattgccctcgaccgcagcatgattccgctcggctcgtgcacgatgaaactc
aacgccgccgccgagatggagtcgattacctggcctgaattcgggcgtcagcatccattt
gccccggcatctgataccgctgggctgcgtcaacttgttgccgacctacagagttggctg
gtgctgatcaccggttatgacgcggtgtcgctgcaacctaacgcgggctcgcaaggcgag
tatgcgggcctattggcgatccacgagtaccacgccagccggggtgaaccgcatcgcgac
atctgcctgatcccgtccagcgcgcacggcaccaatgccgcgtcagccgccttggccggc
atgcgcgtggtggtggtggactgccacgacaacggcgacgtcgacctcgatgacctgcgc
gctaaggtcggggagcatgccgagcggttgtcggcgctaatgatcacctacccgtccact
cacggcgtgtacgaacacgacatcgccgagatctgcgctgccgtgcacgacgcgggcggc
caggtatacgtcgacggagccaacctcaacgccctggtcggcctggcccggccgggcaag
ttcggcggtgacgtcagtcacctcaacctacacaagacattctgcattccgcacggcggc
ggtggcccaggcgtcggcccggtggcggtgcgggcgcacctggcaccgtttctgccaggt
caccccttcgcccccgagctgcccaagggctatccggtgtcgtcggcaccatatgggtcg
gcttcgattcttccgatcacctgggcatacatccggatgatgggggctgagggactgcgg
gcggcatcgctgacagcgatcacgtcggctaactacattgcgcgccgccttgacgagtat
tacccggtgctgtacaccggcgagaacggcatggtcgcccacgagtgcatcctggacttg
cgcggtatcactaagttgaccggtatcaccgtcgacgatgtcgcaaaacggctggcagac
tatggttttcacgcaccaacgatgagttttccggtggccggtacgctcatggtggagccc
accgagagcgagagcctggccgaagtggacgccttctgcgaggccatgatcggcatccgc
gccgagatcgacaaagtcggggccggggagtggcctgtcgacgacaatccgctgcgcggc
gcaccgcacaccgcgcagtgcctgctggcgtctgattgggaccacccgtatacgcgggaa
caggccgcctacccgctcggcaccgcattccgacccaaggtttggcccgcggtacgtcgc
atcgacggcgcctacggggatcgcaacctggtctgctcatgcccgccggtagaggctttt
gcctaa
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