Mycobacterium tuberculosis H37Ra: MRA_2522
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Entry
MRA_2522 CDS
T00540
Symbol
pdhB
Name
(GenBank) putative 2-oxoisovalerate dehydrogenase E1 component subunit beta
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00280
Valine, leucine and isoleucine degradation
mra00640
Propanoate metabolism
mra00785
Lipoic acid metabolism
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MRA_2522 (pdhB)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MRA_2522 (pdhB)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MRA_2522 (pdhB)
Enzymes [BR:
mra01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MRA_2522 (pdhB)
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Gene cluster
GFIT
Motif
Pfam:
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
ABQ74293
UniProt:
A5U5J3
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All DBs
Position
complement(2821904..2822950)
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AA seq
348 aa
AA seq
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MTQIADRPARPDETLAVAVSDITQSLTMVQAINRALYDAMAADERVLVFGEDVAVEGGVF
RVTEGLADTFGADRCFDTPLAESAIIGIAVGLALRGFVPVPEIQFDGFSYPAFDQVVSHL
AKYRTRTRGEVDMPVTVRIPSFGGIGAAEHHSDSTESYWVHTAGLKVVVPSTPGDAYWLL
RHAIACPDPVMYLEPKRRYHGRGMVDTSRPEPPIGHAMVRRSGTDVTVVTYGNLVSTALS
SADTAEQQHDWSLEVIDLRSLAPLDFDTIAASIQRTGRCVVMHEGPRSLGYGAGLAARIQ
EEMFYQLEAPVLRACGFDTPYPPARLEKLWLPGPDRLLDCVERVLRQP
NT seq
1047 nt
NT seq
+upstream
nt +downstream
nt
atgactcaaatcgcagaccgtccggccaggccggatgagacgcttgcggtagcggtgagc
gacatcacgcagtcgttgaccatggtccaggcgatcaaccgcgccctgtacgacgcgatg
gccgccgacgagcgggtattggtgtttggcgaggatgtcgcggtcgagggtggggtgttt
cgggtgaccgagggactggccgatacgttcggtgcagaccggtgcttcgacacgccactg
gcggagtccgcgatcatcggaatagccgtcgggttggcactacgtggctttgtgccggtg
ccagaaatccagttcgacggcttttcctatccggctttcgaccaagtggtgagccatctg
gccaagtaccggactcgcacccgcggtgaggtggacatgccggtgaccgtccggatcccc
tcgtttggcggtatcggtgcggccgaacatcattcggactccacggagtcctactgggtg
cacaccgcgggcctcaaggtggtggtgccgtcgacacccggtgacgcttactggctgctg
cggcacgctatcgcctgcccggaccccgtgatgtatctggagcccaaacgccgctaccac
ggccgcgggatggtcgacactagccggccggaaccgccgatcgggcacgcgatggtgcgc
cggtccggcaccgatgtgaccgtggtaacgtacggaaacctggtgagcaccgccctgtct
agcgcggatactgcagagcagcaacatgattggagtctggaggttatcgatctgcggtcg
ttggcgccgctggacttcgacaccattgctgcgtcgatccagcgcaccgggcgttgcgtg
gtgatgcacgaagggccgcgcagcctcggctatggtgccggtctggccgcgcgcatccag
gaagagatgttctaccaattggaggctccggtgttgcgtgcctgcggttttgacacaccc
tacccgcctgcgcggttggaaaaattgtggttacccggccccgaccggctgttggactgc
gtcgaacgtgtgctgcgtcagccatga
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