KEGG   Mycobacterium tuberculosis H37Ra: MRA_2789
Entry
MRA_2789          CDS       T00540                                 
Symbol
thyA
Name
(GenBank) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
mra  Mycobacterium tuberculosis H37Ra
Pathway
mra00240  Pyrimidine metabolism
mra00670  One carbon pool by folate
mra01100  Metabolic pathways
mra01232  Nucleotide metabolism
mra04981  Folate transport and metabolism
Module
mra_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mra00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    MRA_2789 (thyA)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    MRA_2789 (thyA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    MRA_2789 (thyA)
Enzymes [BR:mra01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     MRA_2789 (thyA)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-ProteinID: ABQ74567
UniProt: A5U6B7
LinkDB
Position
complement(3085648..3086439)
AA seq 263 aa
MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL
WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR
TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS
YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE
YTYEDIVVKNYDPHPAIKAPVAV
NT seq 792 nt   +upstreamnt  +downstreamnt
gtgacgccatacgaggacctgctgcgcttcgtgctcgaaacgggtacgcccaaatccgac
cgcaccggcaccggaacccgcagcctgttcggccagcagatgcgctatgatttgtcggcc
ggtttcccgctgctcactaccaagaaagtccatttcaaatcggtagcctacgagctgctg
tggtttttgcgcggcgattccaatatcggttggctgcacgagcacggagtcaccatctgg
gacgaatgggcaagtgatacaggcgaactcgggccgatctacggtgtacaatggcgatcg
tggccggctccatccggtgagcacatcgaccagatcagcgcggcgctggatttgctgcgc
accgatcccgattcccggcgcatcatcgtgtcggcctggaacgtcggcgaaatcgagcgg
atggcgctgccgccctgtcatgcgttcttccagttctacgtcgccgatggccggctgagc
tgtcagctctaccaacgcagcgccgacctgtttctgggtgtgccgttcaacatcgccagc
tatgcgttgctcacccacatgatggccgcccaggccggcttgtcggtcggcgagttcatc
tggaccggtggcgactgccacatctacgacaatcacgtcgagcaagtacggctgcagctc
agccgcgagccgcggccatatccgaaactacttctagccgaccgggattcaatcttcgag
tacacctatgaagacatcgttgtgaagaactacgatccgcatccggcgatcaaagctcca
gtcgcggtatga

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