Mycobacterium tuberculosis H37Ra: MRA_3326
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Entry
MRA_3326 CDS
T00540
Symbol
accA3
Name
(GenBank) acetyl-/propionyl-coenzyme A carboxylase alpha chain biotin carboxylase/biotin carboxyl carrier protein
KO
K11263
acetyl-CoA/propionyl-CoA/long-chain acyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein [EC:
6.4.1.2
6.4.1.3
6.4.1.-
6.3.4.14
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00061
Fatty acid biosynthesis
mra00074
Mycolic acid biosynthesis
mra00280
Valine, leucine and isoleucine degradation
mra00620
Pyruvate metabolism
mra00630
Glyoxylate and dicarboxylate metabolism
mra00640
Propanoate metabolism
mra01100
Metabolic pathways
mra01110
Biosynthesis of secondary metabolites
mra01120
Microbial metabolism in diverse environments
mra01200
Carbon metabolism
mra01212
Fatty acid metabolism
Module
mra_M00082
Fatty acid biosynthesis, initiation
mra_M00741
Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA
mra_M00885
Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA)
mra_M00886
Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA and KasB)
mra_M00887
Mycolic acid biosynthesis, meromycolic acid + alpha-carboxyacyl-CoA + trehalose => TMM => TDM/mAGP/GMM
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
MRA_3326 (accA3)
00630 Glyoxylate and dicarboxylate metabolism
MRA_3326 (accA3)
00640 Propanoate metabolism
MRA_3326 (accA3)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
MRA_3326 (accA3)
00074 Mycolic acid biosynthesis
MRA_3326 (accA3)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MRA_3326 (accA3)
Enzymes [BR:
mra01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
MRA_3326 (accA3)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
MRA_3326 (accA3)
6.4.1.3 propionyl-CoA carboxylase
MRA_3326 (accA3)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Biotin_lipoyl_2
Dala_Dala_lig_C
Phage_cement_2
LAL_C2
Peptidase_M23
Motif
Other DBs
NCBI-ProteinID:
ABQ75109
UniProt:
A5U7V9
LinkDB
All DBs
Position
3677140..3678942
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AA seq
600 aa
AA seq
DB search
MASHAGSRIARISKVLVANRGEIAVRVIRAARDAGLPSVAVYAEPDAESPHVRLADEAFA
LGGQTSAESYLDFAKILDAAAKSGANAIHPGYGFLAENADFAQAVIDAGLIWIGPSPQSI
RDLGDKVTARHIAARAQAPLVPGTPDPVKGADEVVAFAEEYGLPIAIKAAHGGGGKGMKV
ARTIDEIPELYESAVREATAAFGRGECYVERYLDKPRHVEAQVIADQHGNVVVAGTRDCS
LQRRYQKLVEEAPAPFLTDFQRKEIHDSAKRICKEAHYHGAGTVEYLVGQDGLISFLEVN
TRLQVEHPVTEETAGIDLVLQQFRIANGEKLDITEDPTPRGHAIEFRINGEDAGRNFLPA
PGPVTKFHPPSGPGVRVDSGVETGSVIGGQFDSMLAKLIVHGADRAEALARARRALNEFG
VEGLATVIPFHRAVVSDPAFIGDANGFSVHTRWIETEWNNTIEPFTDGEPLDEDARPRQK
VVVEIDGRRVEVSLPADLALSNGGGCDPVGVIRRKPKPRKRGAHTGAAASGDAVTAPMQG
TVVKFAVEEGQEVVAGDLVVVLEAMKMENPVTAHKDGTITGLAVEAGAAITQGTVLAEIK
NT seq
1803 nt
NT seq
+upstream
nt +downstream
nt
gtggctagtcacgccggctcgaggatcgctcggatctctaaggttctcgtcgccaatcgc
ggcgagatcgcagtgcgggtgatccgggcggcccgcgacgccggcctgcccagcgtggcg
gtgtacgccgaacccgacgccgagtccccgcatgttcggctggccgacgaggcgttcgcg
ctgggcggccagacctcggcggagtcctatctggacttcgccaagatcctcgacgcggca
gccaagtccggggccaacgccatccaccccggctacggcttcctagcggaaaatgccgac
ttcgcccaggcggtgatcgacgccggcctgatctggatcggccccagcccgcagtcgatc
cgcgacctgggcgacaaggtcacggcccgtcacatcgcggcccgcgctcaggcgcccctg
gtgccgggtacccccgatccggtcaaaggcgccgacgaggtggtggcattcgccgaggag
tacggcctgccgatcgcgatcaaggccgcccacggcggcggcggcaagggcatgaaggtg
gcccgcaccatcgacgagattccggagctgtacgagtcggcggtgcgcgaggccacggcc
gcgttcggccgcggtgagtgctacgtggagcgctatctcgacaagccgcgccacgtcgaa
gcacaggtgatcgccgaccagcacggcaacgtcgtcgtcgccggcacccgggactgctcg
ctgcagcgccgctaccagaagctggtcgaggaggcgcccgcaccgttcctgaccgacttt
caacgcaaagagatccacgactcggccaaacggatttgcaaagaggcccattaccacggc
gccggcaccgtcgaatacctggtcggtcaggacggcttgatctcgttcttggaggtcaac
acgcgccttcaggtagaacacccggtcaccgaggaaaccgcgggcatcgacttggtgctg
cagcaattccggatcgccaacggcgaaaagctggacatcaccgaggatcccaccccgcgc
gggcacgccatcgaattccggatcaacggcgaggacgcggggcgtaacttcctaccggcg
cccgggccggtgacaaagttccacccgccgtccggccccggtgtgcgggtggactccggt
gtcgagaccggctcggtgatcggcggccagttcgactcgatgctggccaagctgatcgtg
cacggtgccgaccgcgccgaggcgctggcgcgggcccggcgcgcgctgaacgagttcggt
gtcgaaggcctggcgacggtcatcccgtttcaccgcgccgtggtgtccgacccggcattc
atcggcgacgcgaacggcttttcggtacatacccgctggatcgagaccgagtggaataac
accatcgagccctttaccgacggcgaacctctcgacgaggacgcccggccgcgtcagaag
gtggtcgtcgaaatcgacggtcgccgcgtcgaagtctcgctgccggctgatctcgcgctg
tccaatggcggcggttgcgacccggtcggtgtcatccggcgcaagcccaagccgcgcaag
cggggtgcgcacaccggcgcggcggcctccggtgacgcggtgaccgcgcctatgcagggc
accgtagttaagttcgcggtcgaagaagggcaagaggtcgtggccggcgacctagtggtg
gtcctcgaggcgatgaagatggaaaacccggtcaccgcgcataaggatggcaccatcacc
gggctggcggtcgaggcgggcgcggccatcacccagggcacggtgctcgccgagatcaag
taa
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