Meiothermus ruber DSM 1279: Mrub_2000
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Entry
Mrub_2000 CDS
T01193
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mrb
Meiothermus ruber DSM 1279
Pathway
mrb00300
Lysine biosynthesis
mrb00550
Peptidoglycan biosynthesis
mrb01100
Metabolic pathways
mrb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mrb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Mrub_2000
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Mrub_2000
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Mrub_2000
Enzymes [BR:
mrb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Mrub_2000
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADD28756
UniProt:
A0A806DB11
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Position
2039024..2040343
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AA seq
439 aa
AA seq
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MVPSNTPKELRPEWVASLTGGQVHPGASVAHDLHWDSRQVGPGVAFFALPGARTHGREFG
QQAVQAGAAFVVSDLNHPGAVQVARPERALLAVGRALRDQFRGSVLAVGGSSGKTTTKEC
LAQGLAWPAPEGNLNNAPGLTRFFFHLEPAEGCVVELGIDRLLEMAELTYLARPDIGVLT
GLGVEHLEGLGNLENVVREESWLLQVSPLRLASVQAAELLDLPNLVTYGIEAGDFRAEGV
EMGLEATRFRFEGKVVHLPYPGVGPVMGALAALAVARMLDKPLAQTIERLAALRLPPGRM
QRLRLGGIDFIHDAYNANPLSFKAGMAFLQAQPGRKWLVLGRMAELGQEALKHHLEAARL
AAAVSPNLVFVGPFAKQQAAEAGGTAVETIEEAVQLLFGKVQPGDLVYLKASRSVGLERL
LELWPRENNPSAPAGKEGA
NT seq
1320 nt
NT seq
+upstream
nt +downstream
nt
atggtaccgtccaacactcctaaggaactccgccctgaatgggtggccagtctgaccggc
ggccaggtgcaccccggtgcctcggtggcccacgacctgcactgggactcccgccaggtt
ggcccgggggtggcctttttcgccctgccgggcgcccgaacgcatgggcgcgagttcggt
cagcaggctgtgcaagccggcgccgctttcgtggtcagcgacctgaaccaccccggtgcg
gtgcaggtggccaggcctgagcgggccttgctggcggttgggcgggccttgcgggatcag
ttcaggggaagcgtgctggcggtaggcggcagctcgggcaagaccaccaccaaggaatgc
ctggcccaggggctggcctggccggccccggaaggcaatcttaacaacgcccccggcctc
acgcgcttctttttccacctggagccggccgaaggctgtgtggtggagctgggcatcgac
cggctgctggaaatggccgaactgacctacctggcccgacccgatatcggggtgctcacc
ggcctgggcgtggagcatctggaagggctggggaacctcgagaacgtcgttcgggaggaa
agctggctgttgcaggtcagccccctgcggctggccagcgtgcaggccgctgagctgctg
gacttacccaacctggtcacctatggcatcgaagccggcgacttccgcgccgaaggggtc
gagatgggcctcgaggccacccgcttccgcttcgagggaaaggttgtccacctcccctac
cccggtgtggggccggtgatgggggcgctggctgcgctggccgtcgcccggatgctggac
aagcccctcgcccagaccatcgagcggctggccgccctccggctgccccccggccggatg
cagcgcctgcggctgggtggtatcgactttatccacgatgcctacaacgccaaccccctg
tcgtttaaggccggaatggcgtttttacaggcgcagcctggccgcaagtggctggtgctg
gggcgcatggccgagctgggccaggaagccttaaagcaccacctcgaggccgcccggctg
gctgctgccgtcagcccaaacctggttttcgtcggcccgtttgcaaaacagcaggccgcc
gaagccggtggaaccgccgtagaaaccatcgaggaggcggtgcagttgctttttggcaaa
gttcaacccggcgacctggtctacctcaaagcctcgcgcagcgtgggcctcgagcgcctc
ctggaactctggccccgagaaaacaacccgtcggcaccggccggaaaggagggggcatga
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