Meiothermus ruber DSM 1279: K649_12550
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Entry
K649_12550 CDS
T02636
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mre
Meiothermus ruber DSM 1279
Pathway
mre00300
Lysine biosynthesis
mre00550
Peptidoglycan biosynthesis
mre01100
Metabolic pathways
mre01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mre00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
K649_12550
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
K649_12550
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
K649_12550
Enzymes [BR:
mre01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
K649_12550
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGK05796
UniProt:
M9XB97
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Position
complement(2514400..2515677)
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AA seq
425 aa
AA seq
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MASLTGGQVHPGASVAHDLHWDSRQVGPGVAFFALPGARTHGREFGQQAVQAGAAFVVSD
LNHPGAVQVARPERALLAVGRALRDQFRGSVLAVGGSSGKTTTKECLAQGLAWPAPEGNL
NNAPGLTRFFFHLEPAEGCVVELGIDRLLEMAELTYLARPDIGVLTGLGVEHLEGLGNLE
NVVREESWLLQVSPLRLASVQAAELLDLPNLVTYGIEAGDFRAEGVEMGLEATRFRFEGK
VVHLPYPGVGPVMGALAALAVARMLDKPLAQTIERLAALRLPPGRMQRLRLGGIDFIHDA
YNANPLSFKAGMAFLQAQPGRKWLVLGRMAELGQEALKHHLEAARLAAAVSPNLVFVGPF
AKQQAAEAGGTAVETIEEAVQLLFGKVQPGDLVYLKASRSVGLERLLELWPRENNPSAPA
GKEGA
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
gtggccagtctgaccggcggccaggtgcaccccggtgcctcggtggcccacgacctgcac
tgggactcccgccaggttggcccgggggtggcctttttcgccctgccgggcgcccgaacg
catgggcgcgagttcggtcagcaggctgtgcaagccggcgccgctttcgtggtcagcgac
ctgaaccaccccggtgcggtgcaggtggccaggcctgagcgggccttgctggcggttggg
cgggccttgcgggatcagttcaggggaagcgtgctggcggtaggcggcagctcgggcaag
accaccaccaaggaatgcctggcccaggggctggcctggccggccccggaaggcaatctt
aacaacgcccccggcctcacgcgcttctttttccacctggagccggccgaaggctgtgtg
gtggagctgggcatcgaccggctgctggaaatggccgaactgacctacctggcccgaccc
gatatcggggtgctcaccggcctgggcgtggagcatctggaagggctggggaacctcgag
aacgtcgttcgggaggaaagctggctgttgcaggtcagccccctgcggctggccagcgtg
caggccgctgagctgctggacttacccaacctggtcacctatggcatcgaagccggcgac
ttccgcgccgaaggggtcgagatgggcctcgaggccacccgcttccgcttcgagggaaag
gttgtccacctcccctaccccggtgtggggccggtgatgggggcgctggctgcgctggcc
gtcgcccggatgctggacaagcccctcgcccagaccatcgagcggctggccgccctccgg
ctgccccccggccggatgcagcgcctgcggctgggtggtatcgactttatccacgatgcc
tacaacgccaaccccctgtcgtttaaggccggaatggcgtttttacaggcgcagcctggc
cgcaagtggctggtgctggggcgcatggccgagctgggccaggaagccttaaagcaccac
ctcgaggccgcccggctggctgctgccgtcagcccaaacctggttttcgtcggcccgttt
gcaaaacagcaggccgccgaagccggtggaaccgccgtagaaaccatcgaggaggcggtg
cagttgctttttggcaaagttcaacccggcgacctggtctacctcaaagcctcgcgcagc
gtgggcctcgagcgcctcctggaactctggccccgagaaaacaacccgtcggcaccggcc
ggaaaggagggggcatga
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