KEGG   Muntiacus reevesi (Reeves' muntjac): 136147120
Entry
136147120         CDS       T10466                                 
Symbol
AKT1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01521  EGFR tyrosine kinase inhibitor resistance
mree01522  Endocrine resistance
mree01524  Platinum drug resistance
mree04010  MAPK signaling pathway
mree04012  ErbB signaling pathway
mree04014  Ras signaling pathway
mree04015  Rap1 signaling pathway
mree04022  cGMP-PKG signaling pathway
mree04024  cAMP signaling pathway
mree04062  Chemokine signaling pathway
mree04066  HIF-1 signaling pathway
mree04068  FoxO signaling pathway
mree04071  Sphingolipid signaling pathway
mree04072  Phospholipase D signaling pathway
mree04140  Autophagy - animal
mree04150  mTOR signaling pathway
mree04151  PI3K-Akt signaling pathway
mree04152  AMPK signaling pathway
mree04210  Apoptosis
mree04211  Longevity regulating pathway
mree04213  Longevity regulating pathway - multiple species
mree04218  Cellular senescence
mree04261  Adrenergic signaling in cardiomyocytes
mree04370  VEGF signaling pathway
mree04371  Apelin signaling pathway
mree04380  Osteoclast differentiation
mree04510  Focal adhesion
mree04517  IgSF CAM signaling
mree04518  Integrin signaling
mree04550  Signaling pathways regulating pluripotency of stem cells
mree04611  Platelet activation
mree04613  Neutrophil extracellular trap formation
mree04620  Toll-like receptor signaling pathway
mree04625  C-type lectin receptor signaling pathway
mree04630  JAK-STAT signaling pathway
mree04660  T cell receptor signaling pathway
mree04662  B cell receptor signaling pathway
mree04664  Fc epsilon RI signaling pathway
mree04666  Fc gamma R-mediated phagosome formation
mree04668  TNF signaling pathway
mree04722  Neurotrophin signaling pathway
mree04725  Cholinergic synapse
mree04728  Dopaminergic synapse
mree04810  Regulation of actin cytoskeleton
mree04910  Insulin signaling pathway
mree04914  Progesterone-mediated oocyte maturation
mree04915  Estrogen signaling pathway
mree04917  Prolactin signaling pathway
mree04919  Thyroid hormone signaling pathway
mree04920  Adipocytokine signaling pathway
mree04922  Glucagon signaling pathway
mree04923  Regulation of lipolysis in adipocytes
mree04926  Relaxin signaling pathway
mree04929  GnRH secretion
mree04931  Insulin resistance
mree04932  Non-alcoholic fatty liver disease
mree04933  AGE-RAGE signaling pathway in diabetic complications
mree04935  Growth hormone synthesis, secretion and action
mree04936  Alcoholic liver disease
mree04973  Carbohydrate digestion and absorption
mree05010  Alzheimer disease
mree05017  Spinocerebellar ataxia
mree05132  Salmonella infection
mree05135  Yersinia infection
mree05142  Chagas disease
mree05145  Toxoplasmosis
mree05152  Tuberculosis
mree05160  Hepatitis C
mree05161  Hepatitis B
mree05162  Measles
mree05163  Human cytomegalovirus infection
mree05164  Influenza A
mree05165  Human papillomavirus infection
mree05166  Human T-cell leukemia virus 1 infection
mree05167  Kaposi sarcoma-associated herpesvirus infection
mree05168  Herpes simplex virus 1 infection
mree05169  Epstein-Barr virus infection
mree05170  Human immunodeficiency virus 1 infection
mree05200  Pathways in cancer
mree05205  Proteoglycans in cancer
mree05207  Chemical carcinogenesis - receptor activation
mree05208  Chemical carcinogenesis - reactive oxygen species
mree05210  Colorectal cancer
mree05211  Renal cell carcinoma
mree05212  Pancreatic cancer
mree05213  Endometrial cancer
mree05214  Glioma
mree05215  Prostate cancer
mree05218  Melanoma
mree05220  Chronic myeloid leukemia
mree05221  Acute myeloid leukemia
mree05222  Small cell lung cancer
mree05223  Non-small cell lung cancer
mree05224  Breast cancer
mree05225  Hepatocellular carcinoma
mree05226  Gastric cancer
mree05230  Central carbon metabolism in cancer
mree05231  Choline metabolism in cancer
mree05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mree05415  Diabetic cardiomyopathy
mree05417  Lipid and atherosclerosis
mree05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136147120 (AKT1)
   04012 ErbB signaling pathway
    136147120 (AKT1)
   04014 Ras signaling pathway
    136147120 (AKT1)
   04015 Rap1 signaling pathway
    136147120 (AKT1)
   04370 VEGF signaling pathway
    136147120 (AKT1)
   04371 Apelin signaling pathway
    136147120 (AKT1)
   04630 JAK-STAT signaling pathway
    136147120 (AKT1)
   04668 TNF signaling pathway
    136147120 (AKT1)
   04066 HIF-1 signaling pathway
    136147120 (AKT1)
   04068 FoxO signaling pathway
    136147120 (AKT1)
   04072 Phospholipase D signaling pathway
    136147120 (AKT1)
   04071 Sphingolipid signaling pathway
    136147120 (AKT1)
   04024 cAMP signaling pathway
    136147120 (AKT1)
   04022 cGMP-PKG signaling pathway
    136147120 (AKT1)
   04151 PI3K-Akt signaling pathway
    136147120 (AKT1)
   04152 AMPK signaling pathway
    136147120 (AKT1)
   04150 mTOR signaling pathway
    136147120 (AKT1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    136147120 (AKT1)
   04518 Integrin signaling
    136147120 (AKT1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    136147120 (AKT1)
  09143 Cell growth and death
   04210 Apoptosis
    136147120 (AKT1)
   04218 Cellular senescence
    136147120 (AKT1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    136147120 (AKT1)
   04550 Signaling pathways regulating pluripotency of stem cells
    136147120 (AKT1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    136147120 (AKT1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    136147120 (AKT1)
   04613 Neutrophil extracellular trap formation
    136147120 (AKT1)
   04620 Toll-like receptor signaling pathway
    136147120 (AKT1)
   04625 C-type lectin receptor signaling pathway
    136147120 (AKT1)
   04660 T cell receptor signaling pathway
    136147120 (AKT1)
   04662 B cell receptor signaling pathway
    136147120 (AKT1)
   04664 Fc epsilon RI signaling pathway
    136147120 (AKT1)
   04666 Fc gamma R-mediated phagosome formation
    136147120 (AKT1)
   04062 Chemokine signaling pathway
    136147120 (AKT1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    136147120 (AKT1)
   04922 Glucagon signaling pathway
    136147120 (AKT1)
   04923 Regulation of lipolysis in adipocytes
    136147120 (AKT1)
   04920 Adipocytokine signaling pathway
    136147120 (AKT1)
   04929 GnRH secretion
    136147120 (AKT1)
   04915 Estrogen signaling pathway
    136147120 (AKT1)
   04914 Progesterone-mediated oocyte maturation
    136147120 (AKT1)
   04917 Prolactin signaling pathway
    136147120 (AKT1)
   04926 Relaxin signaling pathway
    136147120 (AKT1)
   04935 Growth hormone synthesis, secretion and action
    136147120 (AKT1)
   04919 Thyroid hormone signaling pathway
    136147120 (AKT1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    136147120 (AKT1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    136147120 (AKT1)
  09156 Nervous system
   04725 Cholinergic synapse
    136147120 (AKT1)
   04728 Dopaminergic synapse
    136147120 (AKT1)
   04722 Neurotrophin signaling pathway
    136147120 (AKT1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    136147120 (AKT1)
  09149 Aging
   04211 Longevity regulating pathway
    136147120 (AKT1)
   04213 Longevity regulating pathway - multiple species
    136147120 (AKT1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136147120 (AKT1)
   05205 Proteoglycans in cancer
    136147120 (AKT1)
   05207 Chemical carcinogenesis - receptor activation
    136147120 (AKT1)
   05208 Chemical carcinogenesis - reactive oxygen species
    136147120 (AKT1)
   05230 Central carbon metabolism in cancer
    136147120 (AKT1)
   05231 Choline metabolism in cancer
    136147120 (AKT1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136147120 (AKT1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    136147120 (AKT1)
   05212 Pancreatic cancer
    136147120 (AKT1)
   05225 Hepatocellular carcinoma
    136147120 (AKT1)
   05226 Gastric cancer
    136147120 (AKT1)
   05214 Glioma
    136147120 (AKT1)
   05221 Acute myeloid leukemia
    136147120 (AKT1)
   05220 Chronic myeloid leukemia
    136147120 (AKT1)
   05218 Melanoma
    136147120 (AKT1)
   05211 Renal cell carcinoma
    136147120 (AKT1)
   05215 Prostate cancer
    136147120 (AKT1)
   05213 Endometrial cancer
    136147120 (AKT1)
   05224 Breast cancer
    136147120 (AKT1)
   05222 Small cell lung cancer
    136147120 (AKT1)
   05223 Non-small cell lung cancer
    136147120 (AKT1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    136147120 (AKT1)
   05170 Human immunodeficiency virus 1 infection
    136147120 (AKT1)
   05161 Hepatitis B
    136147120 (AKT1)
   05160 Hepatitis C
    136147120 (AKT1)
   05164 Influenza A
    136147120 (AKT1)
   05162 Measles
    136147120 (AKT1)
   05168 Herpes simplex virus 1 infection
    136147120 (AKT1)
   05163 Human cytomegalovirus infection
    136147120 (AKT1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136147120 (AKT1)
   05169 Epstein-Barr virus infection
    136147120 (AKT1)
   05165 Human papillomavirus infection
    136147120 (AKT1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136147120 (AKT1)
   05135 Yersinia infection
    136147120 (AKT1)
   05152 Tuberculosis
    136147120 (AKT1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    136147120 (AKT1)
   05142 Chagas disease
    136147120 (AKT1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136147120 (AKT1)
   05017 Spinocerebellar ataxia
    136147120 (AKT1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136147120 (AKT1)
   05418 Fluid shear stress and atherosclerosis
    136147120 (AKT1)
   05415 Diabetic cardiomyopathy
    136147120 (AKT1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    136147120 (AKT1)
   04932 Non-alcoholic fatty liver disease
    136147120 (AKT1)
   04931 Insulin resistance
    136147120 (AKT1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    136147120 (AKT1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136147120 (AKT1)
   01524 Platinum drug resistance
    136147120 (AKT1)
   01522 Endocrine resistance
    136147120 (AKT1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mree01001]
    136147120 (AKT1)
Enzymes [BR:mree01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     136147120 (AKT1)
Protein kinases [BR:mree01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   136147120 (AKT1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 PH_11 Seadorna_VP7
Other DBs
NCBI-GeneID: 136147120
NCBI-ProteinID: XP_065762407
LinkDB
Position
15:complement(65197414..65217714)
AA seq 480 aa
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDLEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDF
RSGSPGESSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFPEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLSPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFASIVWQDVYEKK
LNPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMEGLDSERRPHFPQFSYSASGTA
NT seq 1443 nt   +upstreamnt  +downstreamnt
atgaacgacgtggccatcgtgaaggagggctggctccacaagcgaggtgagtacatcaag
acctggaggccgcgttacttcctcctaaagaatgatggcaccttcattggctacaaggag
cggccgcaggacctggagcagcgagagtcgcccctcaacaacttctccgtggcccaatgc
cagttgatgaagacggagcggccgcggcccaacaccttcattatccgctgcctgcagtgg
accacagtcatcgagcgcacgttccacgtggagacgcccgaggagcgggaggagtggacc
accgccatccagacggtggccgacgggctcaagaggcaggaggaggagacgatggacttc
cggtcgggctcccccggcgagagctcgggggccgaggagatggaggtgtcgctggccaag
cccaagcaccgcgtgaccatgaatgagtttgagtacctgaagctgctgggcaaaggcacc
tttgggaaggtgatcctggtgaaggagaaggccacaggccgctactacgccatgaagatc
ctgaagaaagaggtcatcgtggctaaggacgaggtggcccacacgctcacggagaaccgc
gttctccagaactcccggcacccgttcctgacggccctgaagtactccttccagacccac
gaccgcctgtgcttcgtcatggaatacgccaacgggggcgagctcttcttccacctgtcc
cgggagcgggtgtttcccgaggaccgggcccgcttctacggcgcggagatcgtgtcggcc
ctggattacctgcactcggagaagaacgtggtgtaccgggacctcaagctggagaacctc
atgctggacaaggacgggcacatcaagatcaccgactttggactgtgcaaggagggcatc
aaggacggcgccaccatgaagactttctgcgggacccccgagtacctggcccctgaggtg
ctggaggacaacgactacggccgcgcggtggactggtgggggctgggcgtggtcatgtac
gagatgatgtgcggccgcctgcccttctacaaccaggaccacgagaagctcttcgagctc
atcctcatggaggagatccgcttcccgcgcacactcagcccggaggccaagtccctgctc
tcggggcttctcaagaaggaccccaagcagcggcttggcgggggctctgaggacgccaag
gagatcatgcagcaccgattcttcgccagcatcgtgtggcaggatgtgtacgagaagaag
ctcaacccgcccttcaagcctcaggtcacgtctgagacagacaccaggtattttgacgag
gagttcacggcccagatgatcaccatcacgccacccgaccaagacgacagcatggaggga
ctggacagcgagcggaggccccacttcccccagttctcctactcggccagcggcacggcc
tga

DBGET integrated database retrieval system