Muntiacus reevesi (Reeves' muntjac): 136148094
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Entry
136148094 CDS
T10466
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mree Muntiacus reevesi (Reeves' muntjac)
Pathway
mree00010
Glycolysis / Gluconeogenesis
mree00020
Citrate cycle (TCA cycle)
mree00620
Pyruvate metabolism
mree00785
Lipoic acid metabolism
mree01100
Metabolic pathways
mree01200
Carbon metabolism
mree01210
2-Oxocarboxylic acid metabolism
mree04066
HIF-1 signaling pathway
mree04922
Glucagon signaling pathway
mree05230
Central carbon metabolism in cancer
mree05415
Diabetic cardiomyopathy
Module
mree_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mree00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
136148094 (PDHA2)
00020 Citrate cycle (TCA cycle)
136148094 (PDHA2)
00620 Pyruvate metabolism
136148094 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
136148094 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
136148094 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
136148094 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
136148094 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
136148094 (PDHA2)
Enzymes [BR:
mree01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
136148094 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
136148094
NCBI-ProteinID:
XP_065763639
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Position
16:complement(27517044..27518219)
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AA seq
391 aa
AA seq
DB search
MKKMLTAAVSRVLSGVTQKPASRVLAASCKYSNNATFEMKKCDLYRLEEGPPVTTVLTRE
DGLRYYKMMQTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGFSYTRGLTVRSILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGVAL
ACKYKGNNEVCLTLYGDGAANQGQISEAYNMAALWHLPCVFICENNRYGMGTSVERAAAN
TDYYKRGNFIPGLRVDGMDILCVREATKFAADYCRSGKGPILMELLTYRYHGHSMSDPGI
SYRTREEIQSVRSKSDPIMLLKDKMVNNKLASVEELKEIDVEVRKEIDDAAQFAMTDPEP
PLEELGHHIYSSNPPFDIRGANQWIKFQSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctgaccgcggcggtctctcgcgtgctgtctggcgtcacccagaagcca
gctagcagagtgcttgcggcctcctgtaaatattcaaacaatgctacctttgagatgaag
aaatgtgatctttatcggttggaagagggcccgcctgtcaccaccgtgctcacccgggag
gatggactcagatactacaagatgatgcagacggttcgtcgaatggaactgaaggcagat
cagttgtataaacagaaatttattcgtggtttctgtcacttgtgtgatggtcaggaggct
tgttgtgtgggtcttgaggctgggataaaccccacggatcacgtcattacgtcctatcgg
gctcacggcttcagttatacgcggggacttactgtccgatcaattctggcagagctgaca
ggacgaagaggtggttgtgctaaaggaaagggagggtccatgcacatgtatgccaagaac
ttctatgggggcaatggcattgtcggtgctcagggaccgctgggagccggcgttgctctg
gcctgtaagtacaaggggaacaacgaggtgtgcttgactctgtatggcgatggcgctgct
aatcagggccagatatctgaagcttacaatatggcggctttgtggcacttaccttgcgtt
ttcatctgtgagaataaccgctatggaatgggaacatctgtggagagagctgcagccaac
actgattactacaagagaggcaattttatccctggtctaagagtagatggaatggatatt
ctatgtgttcgggaggcaactaagtttgcagctgactattgtagatctggaaaggggccc
atactgatggagctgctgacataccgttatcatggacacagtatgagtgatcctggaatc
agttaccgtacacgagaagaaattcagagcgtaagaagtaagagtgatcccattatgctt
ctcaaagataaaatggtaaacaacaagcttgccagtgttgaagaattgaaggaaattgat
gttgaagtgaggaaagaaattgatgatgcagctcaatttgctatgactgatccggaaccc
cctttggaagaattaggccatcacatctatagcagtaatccaccttttgatattcgtggt
gcaaatcagtggatcaagtttcagtcaatcagttaa
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