Muntiacus reevesi (Reeves' muntjac): 136148559 Help Entry 136148559         CDS       T10466                                  Symbol JAK2 Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism mree  Muntiacus reevesi (Reeves' muntjac) Pathway mree01521   EGFR tyrosine kinase inhibitor resistance mree04062   Chemokine signaling pathway mree04081   Hormone signaling mree04148   Efferocytosis mree04151   PI3K-Akt signaling pathway mree04217   Necroptosis mree04550   Signaling pathways regulating pluripotency of stem cells mree04630   JAK-STAT signaling pathway mree04658   Th1 and Th2 cell differentiation mree04659   Th17 cell differentiation mree04725   Cholinergic synapse mree04917   Prolactin signaling pathway mree04920   Adipocytokine signaling pathway mree04933   AGE-RAGE signaling pathway in diabetic complications mree04935   Growth hormone synthesis, secretion and action mree05140   Leishmaniasis mree05145   Toxoplasmosis mree05152   Tuberculosis mree05161   Hepatitis B mree05164   Influenza A mree05167   Kaposi sarcoma-associated herpesvirus infection mree05168   Herpes simplex virus 1 infection mree05200   Pathways in cancer mree05207   Chemical carcinogenesis - receptor activation mree05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mree05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:mree00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     136148559 (JAK2)    04151 PI3K-Akt signaling pathway     136148559 (JAK2)   09133 Signaling molecules and interaction    04081 Hormone signaling     136148559 (JAK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     136148559 (JAK2)   09143 Cell growth and death    04217 Necroptosis     136148559 (JAK2)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     136148559 (JAK2)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     136148559 (JAK2)    04659 Th17 cell differentiation     136148559 (JAK2)    04062 Chemokine signaling pathway     136148559 (JAK2)   09152 Endocrine system    04920 Adipocytokine signaling pathway     136148559 (JAK2)    04917 Prolactin signaling pathway     136148559 (JAK2)    04935 Growth hormone synthesis, secretion and action     136148559 (JAK2)   09156 Nervous system    04725 Cholinergic synapse     136148559 (JAK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     136148559 (JAK2)    05207 Chemical carcinogenesis - receptor activation     136148559 (JAK2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     136148559 (JAK2)   09172 Infectious disease: viral    05161 Hepatitis B     136148559 (JAK2)    05164 Influenza A     136148559 (JAK2)    05168 Herpes simplex virus 1 infection     136148559 (JAK2)    05167 Kaposi sarcoma-associated herpesvirus infection     136148559 (JAK2)   09171 Infectious disease: bacterial    05152 Tuberculosis     136148559 (JAK2)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     136148559 (JAK2)    05140 Leishmaniasis     136148559 (JAK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     136148559 (JAK2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     136148559 (JAK2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     136148559 (JAK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mree01001]     136148559 (JAK2) Enzymes [BR:mree01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      136148559 (JAK2) Protein kinases [BR:mree01001]  Non-receptor tyrosine kinases   JAK family [OT]    136148559 (JAK2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Jak1_Phl SH2 ABC1 FERM_C_FAK1 RIO1 Kinase-like FERM_M Motif Other DBs NCBI-GeneID:  136148559 NCBI-ProteinID:  XP_065764249 LinkDB All DBs Position 17:complement(36901662..36995442) Genome browser AA seq 1132 aa AA seqDB search MGMACLTMTEMEETSTSPVHQNGDISGNASSVKQIDPVLQVYLYHSLGKAEGDYLKFPTG EYVAEEICVAASKACGITPVYHSMFALMSETERIWYPPNHVFHIDESTRQNVLYRIRFYF PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG MAVLDMMRIAKEKNQTPLDIYSSISYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIEQF SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR GKHKESETLTEQDLQLYCDFPDIIDISIKQANQEGSNESRIVTIHKQDGKSLEIELKSLR EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKTGNQT GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI RNEDLVFNESLGQGTFTKIFKGIRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM MSQLSHKHLILNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA MHFLEEKTLIHGNVCAKNILLIREEDRKTGNLPFIKLSDPGISITVLPKDILQERIPWVP PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE ILKSLQHDNIVKYKGVCYSAGRHNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE LLKNNGRLPRPDGCPDEIYVIMTECWNNNVSQRPSFRDLAVRVDQIRDNMTG NT seq 3399 nt NT seq  +upstreamnt  +downstreamnt atgggaatggcttgccttacaatgacagaaatggaagaaacctccacatcccctgtacat cagaatggtgatatttctggaaatgctagttctgtgaagcaaatagatccagtcctacag gtctatctttatcattcccttgggaaagctgagggggattatctgaagtttccaactgga gagtatgttgctgaagagatttgtgttgctgcttctaaagcttgtggaatcacacctgtg tatcatagtatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccat gtcttccatatagatgaatcaaccaggcaaaatgtactctacagaatcagattttacttt ccttactggtattgtaatggcagcaacagaacctatcgacatggaatatctcgaggtgct gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggcggcatgat tttttacatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg atggcagtgttagatatgatgagaatagccaaagaaaagaatcaaaccccactggacatc tatagctctatcagctacaagacatttttgccaaaatgtgttcgagcaaagatccaagag tatcatattttgacaaggaagagaataaggtacagatttcgcagatttattgagcaattc agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact cttcagtctgccttctacacagagcagtttgaagtaaaagaacctggaagaggtccttca ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga gggaaacataaagaaagtgagacactgacagaacaggatttacagttgtattgtgatttt cctgatattattgatatcagtattaaacaagcaaatcaagaaggctcaaatgaaagcaga attgtaactattcataagcaagatggtaaaagtctagaaattgagcttaagtcattaaga gaagctttgtcttttgtgtcattaattgatggatattatagattaactgcagatgcacat cattatctttgtaaagaagtagcacctccgatggtgcttgaaaatatacaaagcaactgt catggcccaatttcaatggattttgctatcagtaaactgaagaaaacaggtaatcagact ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct gttgagcgagaaaatgttattgaatataagcactgtttgattacaaaaaatgagaatgga gaatacaacctcagtggtactaagaagaacttcagtaatcttaaagatcttctgaattgc taccagatggaaactgttcgctcagacagtataattttccaatttactaaatgctgtccc ccaaagccaaaagacaaatcaaaccttctagtcttcagaaccaatggtatttctgatgta ccaacctcaccaactttacaaaggcataataatgtgaaccaaatggtgttccacaaaatt agaaatgaagatttggtatttaatgaaagccttggccaaggaacttttacaaaaattttt aaaggcataagaagagaaataggagactatggtcagctgcatgaaacagaagttctttta aaagttctggataaagcgcatagaaactattcagagtctttctttgaagcagcaagcatg atgagccagctttctcacaaacatctgattttaaattatggagtatgtgtctgtggagag gagaatattctggttcaggaatttgtaaaatttggatcactagatacatatctgaaaaag aataaaaattctataaatatattatggaaacttgaagtggctaaacagttggcatgggcc atgcattttctagaagaaaaaacccttattcatgggaatgtgtgcgccaaaaatattctt cttatcagagaagaagacaggaagacaggaaatcttcctttcatcaaacttagtgatcct ggcattagtattacagttttgccaaaagacatcctgcaggagagaataccatgggtacca cctgaatgcattgaaaatcctaaaaatctaaacctggcaacagacaaatggagttttggt accacattgtgggaaatctgtagtggaggagataagcctctgagtgctttggattctcaa agaaaactacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta gcaaatcttattaataattgcatggattatgaaccagattttagaccttctttcagagcc attataagagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac atgttaccaaatatgagaataggtgccctagggttttctggtgcttttgaagaccgagac cctacacaatttgaagaaagacacttgaaatttctacagcaacttggcaagggtaatttt gggagtgtggagatgtgccggtatgaccctctacaagacaatactggggaggtggtggct gtgaaaaagctccagcacagtactgaagagcacctcagagacttcgaaagagaaattgaa attcttaaatccttgcagcatgacaacattgtaaagtacaaaggagtctgctatagtgct ggccggcataatctaagattaattatggagtatttaccatatggaagtttacgagactat ctccaaaaacataaagaacggatagatcataaaaaacttctgcagtacacatctcagata tgcaagggtatggaatatcttggtacaaaaaggtatatccacagggatctggcgacaagg aatatactagtggagaatgaaaacagagttaaaataggagattttggattaaccaaagtc ttgccacaagacaaagagtactacaaagtgaaagaacctggtgaaagtcccatattctgg tatgcaccagagtcactgacagagagcaaattttccgtggcctcagatgtttggagcttc ggagtggttctctatgaactcttcacgtacattgagaagagtaaaagcccgccagcggaa tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaa ctcctgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatgtg attatgacagaatgctggaacaataatgtaagccagcgcccctctttcagagacctagct gttcgagttgatcaaataagggacaacatgactggatga

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