KEGG   Muntiacus reevesi (Reeves' muntjac): 136149127
Entry
136149127         CDS       T10466                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01521  EGFR tyrosine kinase inhibitor resistance
mree01522  Endocrine resistance
mree04012  ErbB signaling pathway
mree04066  HIF-1 signaling pathway
mree04140  Autophagy - animal
mree04150  mTOR signaling pathway
mree04151  PI3K-Akt signaling pathway
mree04152  AMPK signaling pathway
mree04211  Longevity regulating pathway
mree04213  Longevity regulating pathway - multiple species
mree04350  TGF-beta signaling pathway
mree04371  Apelin signaling pathway
mree04666  Fc gamma R-mediated phagocytosis
mree04714  Thermogenesis
mree04910  Insulin signaling pathway
mree04931  Insulin resistance
mree05163  Human cytomegalovirus infection
mree05165  Human papillomavirus infection
mree05170  Human immunodeficiency virus 1 infection
mree05200  Pathways in cancer
mree05205  Proteoglycans in cancer
mree05207  Chemical carcinogenesis - receptor activation
mree05210  Colorectal cancer
mree05212  Pancreatic cancer
mree05221  Acute myeloid leukemia
mree05224  Breast cancer
mree05225  Hepatocellular carcinoma
mree05226  Gastric cancer
mree05231  Choline metabolism in cancer
mree05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    136149127 (RPS6KB1)
   04350 TGF-beta signaling pathway
    136149127 (RPS6KB1)
   04371 Apelin signaling pathway
    136149127 (RPS6KB1)
   04066 HIF-1 signaling pathway
    136149127 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    136149127 (RPS6KB1)
   04152 AMPK signaling pathway
    136149127 (RPS6KB1)
   04150 mTOR signaling pathway
    136149127 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    136149127 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    136149127 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    136149127 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    136149127 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    136149127 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    136149127 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136149127 (RPS6KB1)
   05205 Proteoglycans in cancer
    136149127 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    136149127 (RPS6KB1)
   05231 Choline metabolism in cancer
    136149127 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136149127 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    136149127 (RPS6KB1)
   05212 Pancreatic cancer
    136149127 (RPS6KB1)
   05225 Hepatocellular carcinoma
    136149127 (RPS6KB1)
   05226 Gastric cancer
    136149127 (RPS6KB1)
   05221 Acute myeloid leukemia
    136149127 (RPS6KB1)
   05224 Breast cancer
    136149127 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    136149127 (RPS6KB1)
   05163 Human cytomegalovirus infection
    136149127 (RPS6KB1)
   05165 Human papillomavirus infection
    136149127 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    136149127 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136149127 (RPS6KB1)
   01522 Endocrine resistance
    136149127 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mree01001]
    136149127 (RPS6KB1)
Enzymes [BR:mree01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     136149127 (RPS6KB1)
Protein kinases [BR:mree01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   136149127 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 136149127
NCBI-ProteinID: XP_065765160
LinkDB
Position
18:complement(50704737..50745034)
AA seq 525 aa
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSALSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacgacggaggcgggacggtttctacccagcgccggacttccgagacagggaa
gctgaggacatggcaggggtgtttgacatagacctggaccagccggaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggagcattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgagtacttggtaaaggg
ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaataccgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcctttcattgtggatttaatttat
gcctttcagaccggtggaaaactctacctcatccttgagtatctcagcggaggagaatta
tttatgcagttagaaagagaaggaatatttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcacgtcaaactaacagattttggactatgc
aaagaatctattcatgacggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgagatcttgatgagaagtggccacaaccgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccgttcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacgcaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggatgctggagaagttcaagctcatccattcttcagacatattaactgggaagaactg
ctggctcggaaggtggagccccccttcaaacctcttttgcaatcggaagaggatgtgagt
cagtttgattccaagtttacacgtcagacacctgttgacagcccagatgactcagctctc
agcgaaagtgccaaccaggtcttcctgggttttacatatgtggctccatctgtacttgaa
agcgtgaaagaaaagttttcctttgaaccaaaaatccgatcccctcgaagatttattggc
agcccacgaacacctgtcagcccagtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacggcaaatccgcagacgcctgtggaatacccaatggagacaagtggg
atagagcagatggacgtgacgatgagcggggaggcttcagcaccgcttccaatacgacag
ccaaactccggaccgtacaaaaagcaagcttttcccatgatctccaaacgaccagagcac
ctgcgtatgaatctatga

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