Muntiacus reevesi (Reeves' muntjac): 136151384
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Entry
136151384 CDS
T10466
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mree Muntiacus reevesi (Reeves' muntjac)
Pathway
mree00270
Cysteine and methionine metabolism
mree00480
Glutathione metabolism
mree01100
Metabolic pathways
mree01240
Biosynthesis of cofactors
mree04216
Ferroptosis
Module
mree_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mree00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
136151384 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
136151384 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
136151384 (GCLC)
Enzymes [BR:
mree01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
136151384 (GCLC)
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Gene cluster
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
136151384
NCBI-ProteinID:
XP_065768538
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All DBs
Position
20:9147830..9189933
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AA seq
638 aa
AA seq
DB search
MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
EKKKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMRKRRKEATSLLRENQALCTITSFPRLGCPGFTLPEFKPSPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPTPFIETFPEDEEAAKAAKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTKDKEIYEQLLQ
EGLDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGQFYFRKDICKAGGNAVVDGCGKAAGSAEPAAEEYTLMTIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIAKHPDYKQDSVITDQMNY
SLLLKCNQIANESCECPELLGPAFRKVRYSGNKTDSPT
NT seq
1917 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggagacccagcgccacgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccga
cacaaggacgtgctcaagtggggcgatgaggtggagtacatgttggtgtcttttgatcat
gaaaagaaaaaagcccagttggtcctgtctggagaggaacttcttgaaactctgcaagaa
aaaggggaaaggacaaacccaaaccatccgaccctttggagaccagaatatgggagctac
atgatcgaggggacaccggggcagccgtatggcgggaccatgtctgagttcaacacggtt
gaggacaacatgaggaaacggcgcaaagaggccacatccctcctgcgggaaaaccaggcc
ctctgcacaatcacatcctttcccagattaggctgccctgggttcacgctgcccgagttc
aaacccagcccggtggaaggaggcgcttccaagtccctcttcttcccggatgaagcgatc
aacaagcacccacgcttcagcacgctcaccaggaatatccggcaccggaggggcgagaaa
gtggtcatcaacgtgcccatctttaaggacaagaacaccccaactccatttatagagact
tttcctgaggacgaggaggccgcgaaggccgctaagcccgaccacatttacatggacgcc
atgggcttcgggatgggcaactgctgcctgcaggtaacgttccaagcctgcagcatatcc
gaggccagatacctttatgatcagttggctaccatctgcccaattgttatggctttgagc
gctgcgtcacctttttaccgaggctatgtgtcagacattgattgtcgctggggcgtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccactgaagaacaac
cactataggatcagtaagtcccgatacgattcgatagacagttacttatctgagtgcggt
gagaaatacaatgacattgacctgacaaaagacaaagaaatctacgaacagctgttgcag
gaaggcctcgaccacctgctggcccagcacgtggcgcacctcttcatcagagacccgctg
actctgtttgaagagaaaatccacctggatgatgccaacgagtccgaccactttgagaat
attcagtccacaaattggcagacaatgagattcaagcctcctcctccaaattctgacatt
gggtggagagtggaattccggcccatggaggttcagctgacagacttcgagaactccgca
tacgtggtgttcgtggtgctgctcaccagggtcatcctgtcctacaaactggactttctc
atcccgctgtcgaaggttgatgagaacatgaaggtcgcccagaagcgagatgccgtcctg
cagggacagttttatttcagaaaagacatttgcaaagcaggtggcaacgctgtggtggac
ggctgcggcaaggccgcgggcagcgcagagccagcggccgaggagtacacgctcatgacc
atcgacaccatcatcaatggcaaggaaggtgtgttccctgggctgatccccattctgaac
tcctacctggagaacatggaggtggatgtggacaccagatgcagcattctgaactacttg
aagctgatcaagaagagagcatctggcgaattaatgacagttgccaaatggatgagggag
tttatcgcaaagcatcctgactacaagcaggacagtgtaataactgaccagatgaactat
agccttcttctaaagtgtaatcaaatcgcaaacgaatcatgtgagtgcccagagttactc
ggaccagcgtttaggaaagtaaggtacagtggaaataaaaccgactctcccacctag
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