KEGG   Muntiacus reevesi (Reeves' muntjac): 136159455
Entry
136159455         CDS       T10466                                 
Symbol
GNAS
Name
(RefSeq) guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas isoform X1
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01522  Endocrine resistance
mree04015  Rap1 signaling pathway
mree04020  Calcium signaling pathway
mree04024  cAMP signaling pathway
mree04072  Phospholipase D signaling pathway
mree04081  Hormone signaling
mree04082  Neuroactive ligand signaling
mree04261  Adrenergic signaling in cardiomyocytes
mree04270  Vascular smooth muscle contraction
mree04540  Gap junction
mree04611  Platelet activation
mree04713  Circadian entrainment
mree04714  Thermogenesis
mree04724  Glutamatergic synapse
mree04726  Serotonergic synapse
mree04728  Dopaminergic synapse
mree04730  Long-term depression
mree04750  Inflammatory mediator regulation of TRP channels
mree04911  Insulin secretion
mree04912  GnRH signaling pathway
mree04913  Ovarian steroidogenesis
mree04915  Estrogen signaling pathway
mree04916  Melanogenesis
mree04918  Thyroid hormone synthesis
mree04921  Oxytocin signaling pathway
mree04922  Glucagon signaling pathway
mree04923  Regulation of lipolysis in adipocytes
mree04924  Renin secretion
mree04925  Aldosterone synthesis and secretion
mree04926  Relaxin signaling pathway
mree04927  Cortisol synthesis and secretion
mree04928  Parathyroid hormone synthesis, secretion and action
mree04934  Cushing syndrome
mree04935  Growth hormone synthesis, secretion and action
mree04961  Endocrine and other factor-regulated calcium reabsorption
mree04962  Vasopressin-regulated water reabsorption
mree04970  Salivary secretion
mree04971  Gastric acid secretion
mree04972  Pancreatic secretion
mree04976  Bile secretion
mree05012  Parkinson disease
mree05030  Cocaine addiction
mree05031  Amphetamine addiction
mree05032  Morphine addiction
mree05034  Alcoholism
mree05142  Chagas disease
mree05146  Amoebiasis
mree05163  Human cytomegalovirus infection
mree05165  Human papillomavirus infection
mree05200  Pathways in cancer
mree05207  Chemical carcinogenesis - receptor activation
mree05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    136159455 (GNAS)
   04020 Calcium signaling pathway
    136159455 (GNAS)
   04072 Phospholipase D signaling pathway
    136159455 (GNAS)
   04024 cAMP signaling pathway
    136159455 (GNAS)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    136159455 (GNAS)
   04081 Hormone signaling
    136159455 (GNAS)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    136159455 (GNAS)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    136159455 (GNAS)
  09152 Endocrine system
   04911 Insulin secretion
    136159455 (GNAS)
   04922 Glucagon signaling pathway
    136159455 (GNAS)
   04923 Regulation of lipolysis in adipocytes
    136159455 (GNAS)
   04912 GnRH signaling pathway
    136159455 (GNAS)
   04913 Ovarian steroidogenesis
    136159455 (GNAS)
   04915 Estrogen signaling pathway
    136159455 (GNAS)
   04921 Oxytocin signaling pathway
    136159455 (GNAS)
   04926 Relaxin signaling pathway
    136159455 (GNAS)
   04935 Growth hormone synthesis, secretion and action
    136159455 (GNAS)
   04918 Thyroid hormone synthesis
    136159455 (GNAS)
   04928 Parathyroid hormone synthesis, secretion and action
    136159455 (GNAS)
   04916 Melanogenesis
    136159455 (GNAS)
   04924 Renin secretion
    136159455 (GNAS)
   04925 Aldosterone synthesis and secretion
    136159455 (GNAS)
   04927 Cortisol synthesis and secretion
    136159455 (GNAS)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    136159455 (GNAS)
   04270 Vascular smooth muscle contraction
    136159455 (GNAS)
  09154 Digestive system
   04970 Salivary secretion
    136159455 (GNAS)
   04971 Gastric acid secretion
    136159455 (GNAS)
   04972 Pancreatic secretion
    136159455 (GNAS)
   04976 Bile secretion
    136159455 (GNAS)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    136159455 (GNAS)
   04961 Endocrine and other factor-regulated calcium reabsorption
    136159455 (GNAS)
  09156 Nervous system
   04724 Glutamatergic synapse
    136159455 (GNAS)
   04728 Dopaminergic synapse
    136159455 (GNAS)
   04726 Serotonergic synapse
    136159455 (GNAS)
   04730 Long-term depression
    136159455 (GNAS)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    136159455 (GNAS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    136159455 (GNAS)
   04714 Thermogenesis
    136159455 (GNAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136159455 (GNAS)
   05207 Chemical carcinogenesis - receptor activation
    136159455 (GNAS)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    136159455 (GNAS)
   05165 Human papillomavirus infection
    136159455 (GNAS)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    136159455 (GNAS)
   05142 Chagas disease
    136159455 (GNAS)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    136159455 (GNAS)
  09165 Substance dependence
   05030 Cocaine addiction
    136159455 (GNAS)
   05031 Amphetamine addiction
    136159455 (GNAS)
   05032 Morphine addiction
    136159455 (GNAS)
   05034 Alcoholism
    136159455 (GNAS)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    136159455 (GNAS)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    136159455 (GNAS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    136159455 (GNAS)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mree04147]
    136159455 (GNAS)
   04031 GTP-binding proteins [BR:mree04031]
    136159455 (GNAS)
Exosome [BR:mree04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   136159455 (GNAS)
  Exosomal proteins of other body fluids (saliva and urine)
   136159455 (GNAS)
  Exosomal proteins of colorectal cancer cells
   136159455 (GNAS)
  Exosomal proteins of bladder cancer cells
   136159455 (GNAS)
GTP-binding proteins [BR:mree04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    136159455 (GNAS)
SSDB
Motif
Pfam: G-alpha Arf Gtr1_RagA GTP_EFTU FtsK_SpoIIIE AAA_29
Other DBs
NCBI-GeneID: 136159455
NCBI-ProteinID: XP_065777761
LinkDB
Position
2:complement(55910567..55976707)
AA seq 1000 aa
MGVRNCLDGNNMSGQRNNPLELGEQPEQPPLEAPGAAAPSAGPGPAEEMETPPPHSEPIP
IETEGEVCGPPEVSRPNFQDLSQAIKEAGAHGGYSPPPEEAMPFEVEQASLGGFWPTLEH
PGDTTGTSAGLEAFSPPVMEPGASHEAIPSLGSYSPPPEEAMPFEFEQPDQGDNQPPLQV
SDLAPGGPGSVVFRAPPEEPRAIRPANAGIRGGCSPPHEEDLPFEFDGAALGDDSPPPGL
PRAIPQIDGGGGSQITTVAVSSAILLAPAANEPPLWVPGIIGSPSREAVRPPPHFAGDSP
PMEVSRPPREVGSAPVGVDDAPGDMDSPPVALDDLRIEVSRAPVEREQAEGERPPAEGEA
AEMEGGSATTAAEGGKVPDPGDGAPAAATEAALAAPAAEAASAAPDPPAAGAAPAAPAAP
AAPAAPAAPAASVAGAAPAALVTRGAPVGRAAPVPRAATVPRAATVPRAASVPRATPITW
ANPASGARPEISFLRPPSPEIQAADPPVPQPPRASAWRGRSEPSCCYLYDDQISVSSDSG
DESDDGTFGCRRWFSSKRNRRRRKPRRNLLHNFLVRVFRGCVFGSESPQFRGSFSPKVKK
VALAEKRRQDRKENAGKRGQKWSEKRHSQFTNKQLQNKKMDNSHTHRMLFLGAGESGKST
IVKQMRILHVNGFNGEGGEEDPQAARSNSDGSEKATKVQDIKNNLKEAIETIVAAMSNLV
PPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDC
AQYFLDKIDVIKQDDYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKW
IQCFNDVTAIIFVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQ
DLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRISTASGD
GRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
NT seq 3003 nt   +upstreamnt  +downstreamnt
atgggcgtgcgcaactgcctcgacggcaataatatgtcaggacaacgcaataaccccctt
gaactcggggaacagcccgagcaaccacctttggaggccccaggggcagctgcccccagt
gctgggcctggcccagccgaagagatggagaccccaccgcctcacagcgagcccatcccc
atcgagactgaaggcgaagtctgtggacccccagaggtctccagacccaacttccaggac
ctcagccaggccatcaaggaagccggggcccatggaggctacagcccacctcccgaggaa
gccatgcccttcgaggtcgagcaggccagcttgggaggcttctggcctaccctggagcat
cctggagacaccactgggaccagtgcaggccttgaggccttcagcccaccggtcatggag
cccggagcctcccatgaggccattccaagcctgggaagctacagccctccaccagaagaa
gctatgccttttgagtttgagcagcctgaccagggagacaaccaacctcccttgcaggtc
tcagaccttgctccaggaggcccaggttcggtggtcttcagggctcctcccgaggagccc
cgagccatcagacctgcaaacgcaggcatcagaggaggatgcagccctccccacgaggag
gatctgccattcgagtttgatggagcagccttgggggacgacagcccaccccctgggctc
ccccgagctatcccacagatcgacggcggtgggggcagccagatcacgacagtcgcggtc
tcgagtgcgatcctcctcgctcccgccgcgaacgagccccccctctgggtccccggcatc
atcggcagcccatctcgagaggctgtcagacctcctccacacttcgcgggagacagcccc
ccgatggaggtctccagacccccgcgcgaggttggcagcgcccccgttggggtcgatgac
gctcccggcgacatggacagccccccagtcgcgcttgacgatctgcgcatcgaggtctcc
agagctcccgttgagagagagcaagcagagggagagagacccccagctgagggagaagca
gccgagatggagggaggctcagccaccactgccgcggagggaggcaaggtccccgatccc
ggggacggagcccctgccgctgccaccgaggcagcactggccgctccagccgccgaggca
gcctcggctgctccagaccccccagccgctggagcagcccctgccgctcctgccgcccca
gccgccccagccgctcctgccgccccagccgcttctgtcgctggggcagccccggccgct
cttgtcaccaggggagcccctgttggccgagcggctcctgtcccccgggcagccactgtc
ccccgggcagccactgtcccccgggcagcctccgtcccccgggccactcctatcacctgg
gcaaaccccgcctcgggagcccgacccgagatcagtttccttagacccccaagcccagag
atccaggctgccgatccgcctgttccgcagcctccgcgcgcatctgcctggcggggcagg
tcagagcccagctgctgttacctctacgacgaccagatatcggtcagcagcgacagcgga
gacgaatccgacgatgggaccttcggatgccgccgctggttttcgtccaagcgaaaccgc
cgccgccgaaagccccggcgcaacttgctccacaacttcctcgtccgggtcttccgaggc
tgcgtctttggatccgagagcccccagttcagaggctccttcagccccaaggtcaagaag
gttgccttggcagagaagcgcagacaagaccgcaaggaaaacgcggggaagcgtggccag
aagtggtccgagaagagacacagccagttcaccaacaagcaactccagaacaagaagatg
gacaactcgcatacgcaccgcatgctgtttctaggtgctggagaatctggtaaaagcacc
attgtgaagcaaatgaggatcctgcatgttaatgggtttaatggagagggcggcgaagag
gacccgcaggctgcaaggagcaacagcgatggtagtgagaaggccaccaaagtgcaggac
atcaaaaacaacctgaaagaggccattgaaaccatcgtggccgccatgagcaacctggtg
ccccccgtggagctggccaacccagagaaccagttcagagtggattacattctgagcgtg
atgaacgtgccggactttgatttccctcccgaattctacgagcatgccaaggcgctctgg
gaggatgaaggggtgcgcgcctgctatgagcgctccaacgagtaccagctgattgactgc
gcccagtacttcctggacaagattgatgtcatcaagcaggatgactacgtgcccagcgac
caggatctgcttcgctgccgtgtcctgacttctggaatctttgagaccaagttccaggtg
gacaaagtcaacttccacatgtttgacgtgggcggccagcgcgatgaacgccgcaaatgg
atccaatgcttcaatgatgtgactgccatcatcttcgtggttgccagcagcagctacaac
atggtcattcgggaggacaaccagaccaaccgcctgcaggaggctctgaacctcttcaag
agcatctggaacaacagatggctgcgcaccatctctgtgattctgttcctcaacaagcaa
gatctgctggctgagaaagtccttgctggaaaatcgaagattgaggactactttccagag
tttgctcgctacactactcctgaggatgcgactcccgagcccggagaggacccacgcgtg
acccgggccaagtacttcattcgagatgaatttctgagaatcagcactgctagtggagat
gggcgccactactgctaccctcacttcacctgcgctgtggacaccgagaacatccgccgt
gtgttcaacgactgccgtgacatcatccagcgcatgcacctccgtcagtatgagctgctc
taa

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