KEGG   Muntiacus reevesi (Reeves' muntjac): 136159918
Entry
136159918         CDS       T10466                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01522  Endocrine resistance
mree04010  MAPK signaling pathway
mree04012  ErbB signaling pathway
mree04014  Ras signaling pathway
mree04024  cAMP signaling pathway
mree04068  FoxO signaling pathway
mree04071  Sphingolipid signaling pathway
mree04137  Mitophagy - animal
mree04140  Autophagy - animal
mree04141  Protein processing in endoplasmic reticulum
mree04210  Apoptosis
mree04215  Apoptosis - multiple species
mree04217  Necroptosis
mree04310  Wnt signaling pathway
mree04380  Osteoclast differentiation
mree04510  Focal adhesion
mree04517  IgSF CAM signaling
mree04519  Cadherin signaling
mree04530  Tight junction
mree04620  Toll-like receptor signaling pathway
mree04621  NOD-like receptor signaling pathway
mree04622  RIG-I-like receptor signaling pathway
mree04625  C-type lectin receptor signaling pathway
mree04657  IL-17 signaling pathway
mree04658  Th1 and Th2 cell differentiation
mree04659  Th17 cell differentiation
mree04660  T cell receptor signaling pathway
mree04664  Fc epsilon RI signaling pathway
mree04668  TNF signaling pathway
mree04722  Neurotrophin signaling pathway
mree04723  Retrograde endocannabinoid signaling
mree04728  Dopaminergic synapse
mree04750  Inflammatory mediator regulation of TRP channels
mree04910  Insulin signaling pathway
mree04912  GnRH signaling pathway
mree04914  Progesterone-mediated oocyte maturation
mree04917  Prolactin signaling pathway
mree04920  Adipocytokine signaling pathway
mree04926  Relaxin signaling pathway
mree04930  Type II diabetes mellitus
mree04931  Insulin resistance
mree04932  Non-alcoholic fatty liver disease
mree04933  AGE-RAGE signaling pathway in diabetic complications
mree04935  Growth hormone synthesis, secretion and action
mree04936  Alcoholic liver disease
mree05010  Alzheimer disease
mree05012  Parkinson disease
mree05016  Huntington disease
mree05017  Spinocerebellar ataxia
mree05020  Prion disease
mree05022  Pathways of neurodegeneration - multiple diseases
mree05132  Salmonella infection
mree05133  Pertussis
mree05135  Yersinia infection
mree05142  Chagas disease
mree05145  Toxoplasmosis
mree05152  Tuberculosis
mree05161  Hepatitis B
mree05162  Measles
mree05166  Human T-cell leukemia virus 1 infection
mree05167  Kaposi sarcoma-associated herpesvirus infection
mree05169  Epstein-Barr virus infection
mree05170  Human immunodeficiency virus 1 infection
mree05171  Coronavirus disease
mree05200  Pathways in cancer
mree05208  Chemical carcinogenesis - reactive oxygen species
mree05210  Colorectal cancer
mree05212  Pancreatic cancer
mree05231  Choline metabolism in cancer
mree05415  Diabetic cardiomyopathy
mree05417  Lipid and atherosclerosis
mree05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mree00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    136159918 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136159918 (MAPK8)
   04012 ErbB signaling pathway
    136159918 (MAPK8)
   04014 Ras signaling pathway
    136159918 (MAPK8)
   04310 Wnt signaling pathway
    136159918 (MAPK8)
   04668 TNF signaling pathway
    136159918 (MAPK8)
   04068 FoxO signaling pathway
    136159918 (MAPK8)
   04071 Sphingolipid signaling pathway
    136159918 (MAPK8)
   04024 cAMP signaling pathway
    136159918 (MAPK8)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    136159918 (MAPK8)
   04519 Cadherin signaling
    136159918 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    136159918 (MAPK8)
   04137 Mitophagy - animal
    136159918 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    136159918 (MAPK8)
   04215 Apoptosis - multiple species
    136159918 (MAPK8)
   04217 Necroptosis
    136159918 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    136159918 (MAPK8)
   04530 Tight junction
    136159918 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    136159918 (MAPK8)
   04621 NOD-like receptor signaling pathway
    136159918 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    136159918 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    136159918 (MAPK8)
   04660 T cell receptor signaling pathway
    136159918 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    136159918 (MAPK8)
   04659 Th17 cell differentiation
    136159918 (MAPK8)
   04657 IL-17 signaling pathway
    136159918 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    136159918 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    136159918 (MAPK8)
   04920 Adipocytokine signaling pathway
    136159918 (MAPK8)
   04912 GnRH signaling pathway
    136159918 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    136159918 (MAPK8)
   04917 Prolactin signaling pathway
    136159918 (MAPK8)
   04926 Relaxin signaling pathway
    136159918 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    136159918 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    136159918 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    136159918 (MAPK8)
   04722 Neurotrophin signaling pathway
    136159918 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    136159918 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    136159918 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136159918 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    136159918 (MAPK8)
   05231 Choline metabolism in cancer
    136159918 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    136159918 (MAPK8)
   05212 Pancreatic cancer
    136159918 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    136159918 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    136159918 (MAPK8)
   05161 Hepatitis B
    136159918 (MAPK8)
   05171 Coronavirus disease
    136159918 (MAPK8)
   05162 Measles
    136159918 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136159918 (MAPK8)
   05169 Epstein-Barr virus infection
    136159918 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136159918 (MAPK8)
   05135 Yersinia infection
    136159918 (MAPK8)
   05133 Pertussis
    136159918 (MAPK8)
   05152 Tuberculosis
    136159918 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    136159918 (MAPK8)
   05142 Chagas disease
    136159918 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136159918 (MAPK8)
   05012 Parkinson disease
    136159918 (MAPK8)
   05016 Huntington disease
    136159918 (MAPK8)
   05017 Spinocerebellar ataxia
    136159918 (MAPK8)
   05020 Prion disease
    136159918 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    136159918 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136159918 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    136159918 (MAPK8)
   05415 Diabetic cardiomyopathy
    136159918 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    136159918 (MAPK8)
   04936 Alcoholic liver disease
    136159918 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    136159918 (MAPK8)
   04931 Insulin resistance
    136159918 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    136159918 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    136159918 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mree01001]
    136159918 (MAPK8)
Enzymes [BR:mree01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     136159918 (MAPK8)
Protein kinases [BR:mree01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   136159918 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 RIO1 Kinase-like Kdo FTA2 APH
Other DBs
NCBI-GeneID: 136159918
NCBI-ProteinID: XP_065778827
LinkDB
Position
2:121571580..121663742
AA seq 439 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNADISENWNLSTEIIGLLNVFTPQKSLEEFQDVYIVM
ELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKIL
DFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGT
DHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNK
LKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHT
IEEWKELIYKEVMDLEERTKNGVIRGQPSPLGAAVISGSQHPSSSSSVNDVSSMSTDPTL
ASDTDSSLEASAGPLGCCR
NT seq 1320 nt   +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacagcaatttttatagtgtagaaattggagattctacattc
acagtcctgaaacggtatcagaatttaaaacctataggttcaggagcccaaggaatagta
tgtgcagcttatgatgccattcttgaaagaaacgttgcaatcaagaagctaagccggcca
tttcagaatcaaactcatgctaagcgtgcttacagagaactagttcttatgaaatgtgta
aatcacaaaaatgctgacatttcagaaaactggaaccttagcacagagataattggcctt
ttgaatgtttttacaccacagaaatccctagaagaatttcaagatgtttacatagtcatg
gagctcatggatgcaaatctttgtcaagtgattcagatggaactagatcatgaaagaatg
tcctaccttctctatcagatgctgtgtggaatcaagcaccttcactctgctggaattatt
catcgggacttaaagcccagtaatatagtagtaaaatcagactgcactttgaagattctt
gactttggactggccaggactgcaggaactagttttatgatgacaccttacgtagtgact
cgctactacagagcacctgaggtcatcctaggcatgggctacaaagaaaacgttgacatt
tggtcagttgggtgcatcatgggagaaatgatcaaaggtggtgttttgttcccaggtaca
gatcatattgatcagtggaataaagttattgaacagcttggaacaccatgtcctgaattc
atgaagaaactacaaccaacagtaaggacttatgttgaaaacagacctaaatatgctgga
tatagctttgagaaactcttccctgatgtacttttcccagctgactcggaacacaacaaa
cttaaagccagtcaggcaagggatttgttatccaaaatgctggtaattgatgcatctaaa
aggatttctgtagatgaagctctccagcacccgtatatcaatgtctggtatgatccttct
gaagcagaagctcccccaccaaagatacctgacaagcagttagatgaaagggaacacaca
atagaagagtggaaagaattgatatacaaagaagttatggacttggaggaaagaaccaag
aatggagttatacgggggcagccctctcctttaggtgcagcagtgatcagtggctctcag
catccatcatcatcgtcatctgtcaatgatgtgtcttcaatgtcaacagatccgactttg
gcctcggatacagacagcagtctagaagcatcagctgggcctctgggctgctgtagatga

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