KEGG   Muntiacus reevesi (Reeves' muntjac): 136159996
Entry
136159996         CDS       T10466                                 
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree00562  Inositol phosphate metabolism
mree01100  Metabolic pathways
mree04014  Ras signaling pathway
mree04015  Rap1 signaling pathway
mree04020  Calcium signaling pathway
mree04024  cAMP signaling pathway
mree04070  Phosphatidylinositol signaling system
mree04919  Thyroid hormone signaling pathway
mree04933  AGE-RAGE signaling pathway in diabetic complications
mree05205  Proteoglycans in cancer
Module
mree_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mree00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    136159996 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    136159996 (PLCE1)
   04015 Rap1 signaling pathway
    136159996 (PLCE1)
   04020 Calcium signaling pathway
    136159996 (PLCE1)
   04070 Phosphatidylinositol signaling system
    136159996 (PLCE1)
   04024 cAMP signaling pathway
    136159996 (PLCE1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    136159996 (PLCE1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    136159996 (PLCE1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    136159996 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mree04131]
    136159996 (PLCE1)
Enzymes [BR:mree01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     136159996 (PLCE1)
Membrane trafficking [BR:mree04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    136159996 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    136159996 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like GDPD
Other DBs
NCBI-GeneID: 136159996
NCBI-ProteinID: XP_065779016
LinkDB
Position
2:137878878..138237175
AA seq 2297 aa
MTSEEMAGSVLRPVSQRKVISAQSTVDESNDKVSDINVPKSHPVRQSGETSHTISQLTKL
TEESSGSNVPQIFSVAREKITSDENSNENCWEKSMPDSVKNLNINCNSILKNHQHGPPQS
QFYETCNSITEEGLCLETGIPSSLEGKVFPGIQLEIDRPPMGISPLGTQSAIIETSRAVP
ESNMTVFHLRYEVDRRMSDSLCPLSDNLILDDCGNCVLPTVGEDQEKNYMAYTCQLMELT
SNCDNKNRQLQCDHCDPLNDKYLCFEGSCPKADVVCSSDSFCREDFTDSPPAKTFLSHFE
DFPDNCEDVEEDLFKNKKERSAWLVRRFCKNDKEVKKSVFTGTRAIVRTLPSGHIGLEAL
SYIDQKKNGLLLPPGRVMERLSTVVVRQDGSQGLSEAQWYPIYSAVRRGEATEETIRSLL
HFFAKLPASETAHERISVSPYLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGAR
SSLLNSFGGSTGRMMLKERQPGTSMANSSTLSSSSAGISKELIDLKPLIQFPEEVASILM
EQEQNIYRRVLPVDYLIFLTRGLGTTDRQRSLPSLKASISASILTSQNGEHNALEDLVMR
FNEVSSWVTWLILAAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRS
LETEEEDSPSDGNSSRKNSLKDKARWQFIIGDLLDSENDIFEQSKEWDSHGSEEPQKAFD
HGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWMKPTTAS
PASAKAKLGVLSNTSEPGKFPLLGNAGLSGLVEGILDLFAAKAVYMGHPNIDIHTVCVQN
KLSNMSLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAQAVELFGGRRWSTRNPSPGTSAKSVEKPNSLSISSAK
KKKKILMRGESGEVTDDEMATRKAKTHKESRSRSGSDPQDVNEQEESEANAIMNPPNPLP
SRRAHSLTTTGPPTLAAGTSSPIRPVSSPVLPASNKSPTSAWNSSSCWPGKIKGGMQGFQ
SFMVSDSSMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCDRAGSEAAPLYTNLTIDENV
SGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGVFGV
GILQLNDFLVNCQGEHYTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNFASKN
DESQENVKEMQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGD
DGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTV
FGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQA
QAYNGSNANSPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIP
KRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLN
ASGSSRGKERKSRKSIFGNNPGRMSPGETAPFNKTSGKSSCEGMRQAWEDSPFSVNPTTS
LSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLLF
WLHGIQLVALNYQTDDLSLHLNAAMFEANGGCGYVLKPPVLWDKNCSMYQKFSPLERDLD
NMEPAVYSLTIVSGQNVCPSNSTGSPCIEVDVLGMALDSCHFRTKPIHRNTLNPMWNEQF
LFRVHFEDLVFVRFAVVENNSSVVTAQRIISLKALKRGYRHLQLRNLHNEVLEISSLFIN
SRRMEENSSGNTVPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGATKAKQLLQQ
ILIMDQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIVQILSSWFPEEGYV
GRIVLKTQQENLEEKSIVQDDKEMLLSSEEDSFFVQVHDVSPEQPRTVIKAPRVSTAQDV
IQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTANRKSSTPKASQRVLLDQECVFQAQSK
WKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKTKQPRGPTSPSQVLASENVQNKE
EKPMGGLPSSDTTDYRQ
NT seq 6894 nt   +upstreamnt  +downstreamnt
atgacttctgaagaaatggcaggttctgttctcagacctgtgagtcagagaaaagtgatc
tctgctcagtcaactgtagatgaaagtaatgataaggtctccgacatcaatgttccaaag
tctcatcctgtcaggcagagtggggagacttctcataccatctcgcagctgaccaaactt
acagaagaatcttcaggaagcaacgtgccccagattttctcagtagcaagggagaaaata
accagtgatgagaacagtaatgaaaattgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacagcatattgaaaaaccatcagcatggccctcctcagagc
cagttttatgaaacgtgcaattctatcacagaggaaggtctgtgtttggaaactggaatc
ccttcttcactggaaggaaaggtgttccctggaattcaactggaaatagacagacctccc
atgggcattagtccattaggaactcagtcagccatcatagagacaagcagggcggtccct
gaaagcaacatgacagtatttcacttgcgttacgaggttgacagaagaatgtcagacagt
ctctgtcccctgtcagataacttgattttggatgattgtggaaactgtgtactacctact
gttggtgaggatcaagagaaaaattacatggcgtatacttgccaactgatggaattgaca
agtaactgtgacaataagaataggcagctgcagtgtgatcattgtgaccccttgaatgac
aaatacttgtgctttgaaggctcttgcccaaaggccgatgtggtatgttcaagtgacagc
ttttgcagggaggattttactgacagtccacctgccaagacctttctgagccattttgag
gacttccctgataattgtgaagatgtagaagaagatttgtttaaaaataaaaaggagcgg
tctgcttggttagtgaggagattttgcaaaaatgacaaggaagttaagaaatctgtgttt
actgggacaagggcaattgtgagaaccttgccttctggtcacattggactggaggctttg
agttatattgatcagaagaaaaatggtctcttgttgcctcctgggagagtcatggaacgg
ctgtcaacagtggtggttaggcaagatggttcccaaggtctgtcagaagcccagtggtat
ccgatctacagtgcagtgagaaggggagaagccacagaagaaacaattagatctcttctc
catttcttcgccaagctcccagcctccgagacagcccatgaaaggatcagtgtcagtccg
tacttaaagcaatgtgtccgagacacggtgtgtgagtatcgtgccaccctgcaaaggact
tccatatctcagtacatcaccggctctctcctggaagccaccacatctttaggagcaaga
agcagcctcctcaattcttttggaggatccacgggacgaatgatgctgaaagaacgccaa
ccaggcacgtctatggccaattccagtaccctttcttcaagttcagctgggatcagcaag
gaactgattgatctgaagcccctcatccagttcccagaggaagtcgccagcatcctgatg
gagcaggagcaaaatatttaccgaagggtcttgccagttgactatcttattttcttaacc
cggggcttgggcaccacagaccgccagaggtccctgccctccctcaaagcatccatctca
gcatccattcttacctcccagaatggagagcacaacgccctcgaagatcttgtgatgaga
tttaatgaggtgagctcctgggtgacgtggctgatcctcgcggcaggctccatggaagag
aagcgggaagtcttctcgtacttggttcatgtggccaaatgctgctggaatatgggcaac
tacaatgccgtcatggagttcttggccggcctcaggtcaaggaaagttttaaaaatgtgg
cagtttatggaccagtctgacctggagaccatgaggagcctgaaggacgccatggcccag
cacgagtcttcctgcgaatacaggaaggtggtgacacgagcgctgcacatccccggctgc
aaggtggttccgttctgcggggtgttcctgaaggagctctgtgaggtgctggacggagcc
tctggcctcatgaagctttgcccgaggtacaattcgcaggaagaaactctagagtttgta
gccgattatagtggacaagataatttcttacaacgagtgggacagaatggcttaaagaat
tcagagaaggagtccactgtcaacagcatctttcagatcatcaggagctgcagtcgaagt
ctggagacagaggaggaggacagccccagtgatgggaacagctcaaggaaaaattccctg
aaggataaagcccgatggcagtttataattggagatttgttggattctgaaaatgacatc
tttgagcagtccaaagaatgggactctcatggatcggaagagccacagaaagcctttgac
catgggacggagctcatcccatggtacgtgctgtccatccaagctgatgtgcaccagttc
ctgttgcagggggccacagtcatccactacgatcaggacacgcacctctctgcccgctgc
ttcctccagcttcagcctgacaatagcaccttgacctggatgaaacccaccactgcttcc
ccagccagtgctaaagcaaaacttggtgtgctcagtaacacatctgagcctggcaaattc
ccgttactgggcaatgctggattaagtggcctggtggaggggatcttggatctgtttgca
gcaaaggctgtgtacatgggacaccctaacattgatatacacactgtgtgtgttcagaac
aaattgagtaacatgtctctctcagagactggtgtgacactgctctacgggctgcagacc
acggacaatagattattgcactttgtggcaccaaagcacacagctaaaatgctcttcagt
ggattgttggagctcactagagctgtgaggaagatgaggaagttccctgaccaaagacag
cagtggctgcggaaacagtacgtcagcctttaccaggaggatggacgatatgaaggccca
actttggctcaagctgtggagctgtttggtggcagacgatggagtactcgaaaccccagc
cctgggacatcagcaaagagcgtcgagaagcccaactccttaagtataagcagcgccaag
aaaaagaagaaaatccttatgaggggtgagagtggagaggtgacggatgacgagatggcc
acccgcaaggccaaaacacacaaagagagtcggagccggagtggttctgatcctcaagat
gtcaatgaacaagaagaatcagaggcaaatgccatcatgaaccctcccaaccctctccct
tccagaagagcccactccttgaccacgactgggccccctaccttggctgccgggacatca
tctcccatcaggccagtgtcctcccctgtgctgcctgcttccaacaagagcccgaccagt
gcttggaacagcagcagctgctggccagggaagatcaaaggagggatgcagggctttcag
agcttcatggtttcagacagcagcatgagttttgtggaatttgttgagctgttcaaatca
ttcagtgtgaggagccgcaaggacctgaaggacctctttgacatctacgccgtaccctgt
gatcgagctggctctgaggcagcccccctctataccaacctgaccattgatgaaaatgtc
agcggtcttcagcctgacctagatttgttgaccagaaatgtctcagatttggggttattc
atcaagagtaaacagcagctgtccgacaaccagaggcagatatctgatgccattgctgct
gcaagcattgtgacaaatggcaccggagtggagagcacatctctgggtgtgtttggagtc
ggcatcctccagctcaatgacttcctagtgaattgccaaggagaacactatacttatgac
gaaatcctcagcatcatccagaagttcgagcctagcattagtatgtgtcatcaaggccta
atgtcatttgaaggatttgcaaggtttctaatggataaagataattttgcctcgaaaaac
gatgagtcacaggagaacgttaaagaaatgcagctgcccctctcctactattacattgaa
tcttcacacaatacctacctcacgggccatcagctcaagggagaatcctcagtagaactc
tacagccaggtcctcctgcaaggctgtaggagtgtagagttggactgctgggacggagat
gatggaatgcccatcatttatcatggacacaccctgacaaccaagatccccttcaaggaa
gtggttgaagccatcgatcgcagtgccttcatcaactctgacctacccatcatcatatcg
attgagaaccactgttcattgcctcagcaacgaaaaatggcagaaattttcaagactgtg
tttggagaaaaactggtggctaaattcttatttgagagtgatttctcagatgatccaatg
ctcccctcgcctgaccaactcagaaggaaagtgcttctcaaaaataagaaattaaaagcc
catcagacaccagtggatatcttaaagcaaaaggctcatcagctagcatccatgcaagct
caggcttataacggtagcaatgccaactccccacctgctaataatgaggaagaggaagat
gaagaggatgaatatgattatgattatgaatccctctctgatgacaacattctagaagac
agacctgaaaataaatcatgtaatgacaaacttcagtttgagtataatgaagaaatcccc
aagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtttatgacatggaa
ctgggagaagaattttatcttcctcagaataaaaaggaaagcagacagattgcaccagag
ctttctgaccttgtcatctattgccaagcagtaaaattcccaggcctgtcaactctaaat
gcatctggctcgagccgaggaaaagaaaggaaaagcaggaagtccatttttggcaacaat
ccgggcagaatgagccccggggagacagcaccatttaacaaaacatctggaaaaagttcc
tgtgaaggaatgcgacaggcctgggaggactctcctttctccgtcaacccaaccacgtcc
ctcagcgctatcattagaactcccaaatgctaccatatctcctcgctgaatgaaaatgcc
gccaaacgtctatgtcgcaggtattctcagaaactgatccagcataccgcctgccagctg
ctgaggacgtacccggctgccactcgcatcgactcttccaaccccaaccccctcctgttc
tggctgcatgggatacagctcgtggcactcaactaccagacagatgatctctctttacat
ttgaatgccgccatgtttgaggccaatggtggctgcggttatgttctgaaacccccagtt
ctgtgggacaagaactgttccatgtatcagaagttctcccccttggaaagagacctggac
aacatggagcctgccgtctattctttaactattgtctctgggcagaacgtgtgcccaagt
aatagcacggggagcccatgtatcgaggtcgatgtcttgggcatggccttggacagctgc
cacttccgcacgaagcccatccaccgcaatactctgaatcccatgtggaatgaacagttc
ctcttccgggttcacttcgaagatctcgtatttgttcgttttgctgtcgtggagaacaac
agctcggtggtcactgctcagagaatcatctccctcaaggctctaaagcgaggatatcga
catcttcagctgcgaaatctccacaatgaagtcttggaaatctctagtttattcataaac
agcaggaggatggaagaaaattcctctggcaatactgtgccggcctctctgatgtttaat
acagaagaaagaaaatgtttgcagactcacagagtcacagtgcatggcgtcccaggtcca
gagccctttactgttttctctataaacggagccactaaggcaaagcagcttctccaacaa
attctcattatggatcaagataccaaacctattgccacagactattttttaatggaggaa
aaatatttcatatctaaagagaagaatgaatgtaggaaacaaccgttccagagagccatt
ggtccagaagaagagattgtgcaaattttaagcagctggtttccagaagagggatatgtt
ggcaggattgtcttaaaaacccagcaggaaaacctggaggagaaaagcattgtgcaagat
gacaaggagatgctcctgagctcagaggaggacagcttctttgtccaggtgcacgacgtt
tcccccgagcaaccgcgcacggtcatcaaagcgccccgtgtcagcaccgcgcaggacgtc
attcagcagaccttatgcaaagccaaatattcctatagcatcctaagcaaccccaacccg
agtgactatgtgcttttggaagaggtggtgaaagacaccgccaacaggaagtcttccacc
ccaaaggcctcccagcgtgtccttctggatcaggagtgtgtgtttcaagctcaaagcaag
tggaaaggtgcaggaaaattcatccttaagctaaaggaacaggtgcaggcatctcgagaa
gataaaaaaaaaggcatctcttttgcaagcgaactcaagaagctcaccaagactaaacag
ccccgaggacccacatcaccttctcaggtcttggcctcagaaaatgtccaaaacaaggaa
gagaaacctatgggtggcctgccttccagtgacaccacagactaccgacagtga

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