Muntiacus reevesi (Reeves' muntjac): 136163756
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Entry
136163756 CDS
T10466
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
mree Muntiacus reevesi (Reeves' muntjac)
Pathway
mree00790
Folate biosynthesis
mree01100
Metabolic pathways
mree01240
Biosynthesis of cofactors
mree01523
Antifolate resistance
mree04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mree00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
136163756 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
136163756 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
136163756 (FPGS)
Enzymes [BR:
mree01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
136163756 (FPGS)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
136163756
NCBI-ProteinID:
XP_065784466
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Position
3:complement(8043199..8069273)
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AA seq
584 aa
AA seq
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MSRARCHALFLAAVSPRGATTGVAARRGLSAWPVLQEPGMEYQDAVRTLNTLQTNANYLE
MVKRERGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRSYGL
KTGFFSSPHLVQVRERIRINGQPISSELFTKHFWRLYHRLEETKDDSSCVSMPGYFRFLT
LMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGITSLGIDHTGLLGDTMEKIAWQ
KGGIFKSGVPAFTVPQPDEPLAVLRDRAQQISCPLYLCPPLQALEEGGPPLTLGLEGEHQ
RSNAALALQLARCWLQQKGYQDAGELKASRSSLPGQLPLAPVFQPTPHMQQGLRHTEWPG
RTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALHLCQRPDSGSEVRVLLFNSTGDRDSA
ALLKLLQPCQFDYAIFCPNLAEMASTDNADQQNFTVTLDQVLLRCLTHQQHWSRLHEEQA
SPDPWSTPSREQGGPASLLAPHPPHTHSASSLIFSCISHALQWITQGRDPVFQLPRPPRG
LLAHPVADSGAVVLQEAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1755 nt
NT seq
+upstream
nt +downstream
nt
atgtctcgggcacgctgccacgctctcttcctggcagcggtttctccgcgtggtgcaaca
accggggtcgcagcgcggcgaggcttgagcgcgtggcctgtactgcaggagccaggcatg
gagtatcaggatgctgtgcgcacactcaacaccctgcagaccaatgctaactacttggag
atggtgaagcgtgagcggggtgacccccagacacagctggaagccatgaagctgtacttg
gcacggagtgggctgcaggtggaggacttggaccaactgaacatcatccacatcactggg
accaaggggaagggctccacgtgtgccttcactgaacgtatcctccgaagctacggcctg
aagacggggttctttagctctccccacctggtgcaggtgcgtgagcggatccgcatcaat
gggcagcccataagctccgaactcttcaccaagcacttctggcgcctctaccaccggctg
gaggagaccaaggacgacagcagctgtgtctccatgcccggctacttccgcttcctcacg
ctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggaagtaggc
atcggtggggcttacgactgcaccaacatcatcaggaagcctgtggtgtgtgggatcacc
tctctcggcattgaccacactggccttctgggggacacgatggagaagatcgcatggcag
aaagggggcatttttaagagtggcgtccctgccttcaccgtgccccagcctgacgagccg
ctggcagtgctaagggacagggctcagcagatctcatgtcccctctacctgtgcccacca
ctacaagccctggaggaaggggggccaccgctgaccctgggcctggagggagagcaccag
cggtccaatgctgccctggccttgcagctggcccgctgctggctgcagcagaaaggttac
caggatgccggggagctgaaggcatccaggtccagcctcccggggcagctgcccctggca
cctgtgttccagcccacaccccacatgcagcaggggcttcggcacacggaatggccaggt
cggacgcagttgctgcggcgcgggccccttacctggtacctggacggcgctcacaccacc
agcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcacctatgccagaggccg
gacagcgggtccgaggtgcgcgtcttgctcttcaactccactggggaccgggattccgcg
gccctgctgaagctgctgcagccctgccagtttgactatgccattttctgccctaacctg
gcagagatggcatcaacagacaatgcagaccaacagaacttcacagtgacactggaccag
gtgctgctccgctgcctcacccaccaacagcactggagtcgcctgcacgaggagcaggcc
agcccggacccctggagcacccccagccgggagcagggtgggcccgcatctctgctggcg
cctcacccaccccacactcacagcgccagctccctcatcttcagctgcatctcccacgcc
ttgcagtggatcacccaaggccgggaccctgtctttcagctgccccgtcccccacggggc
ctccttgcccaccctgtggcagacagcggggccgtggtactccaagaggctgccgccatc
cacgtgctggtcacgggcagcctgcacctggtgggcggtgtcctgaagctgctggagccc
tccctgtcccagtag
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