KEGG   Muntiacus reevesi (Reeves' muntjac): 136163777
Entry
136163777         CDS       T10466                                 
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP
  KO
K09490  endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree03060  Protein export
mree04141  Protein processing in endoplasmic reticulum
mree04612  Antigen processing and presentation
mree04918  Thyroid hormone synthesis
mree05012  Parkinson disease
mree05014  Amyotrophic lateral sclerosis
mree05020  Prion disease
mree05022  Pathways of neurodegeneration - multiple diseases
mree05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mree00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03060 Protein export
    136163777 (HSPA5)
   04141 Protein processing in endoplasmic reticulum
    136163777 (HSPA5)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    136163777 (HSPA5)
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    136163777 (HSPA5)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    136163777 (HSPA5)
   05014 Amyotrophic lateral sclerosis
    136163777 (HSPA5)
   05020 Prion disease
    136163777 (HSPA5)
   05022 Pathways of neurodegeneration - multiple diseases
    136163777 (HSPA5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136163777 (HSPA5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mree03110]
    136163777 (HSPA5)
   04131 Membrane trafficking [BR:mree04131]
    136163777 (HSPA5)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mree04147]
    136163777 (HSPA5)
Enzymes [BR:mree01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.10  non-chaperonin molecular chaperone ATPase
     136163777 (HSPA5)
Chaperones and folding catalysts [BR:mree03110]
 Heat shock proteins
  HSP70 / DNAK
   136163777 (HSPA5)
Membrane trafficking [BR:mree04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   ER-Golgi intermediate compartment (ERGIC) proteins
    136163777 (HSPA5)
 Autophagy
  ER-phagy
   ER stress-related proteins
    136163777 (HSPA5)
Exosome [BR:mree04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   136163777 (HSPA5)
  Exosomal proteins of other body fluids (saliva and urine)
   136163777 (HSPA5)
  Exosomal proteins of colorectal cancer cells
   136163777 (HSPA5)
SSDB
Motif
Pfam: HSP70 MreB_Mbl Hydantoinase_A FtsA DDR FGGY_C ParM_N
Other DBs
NCBI-GeneID: 136163777
NCBI-ProteinID: XP_065784527
LinkDB
Position
3:10358638..10362985
AA seq 655 aa
MKLSLVAAVLLLLLGMARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGN
RITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKV
VEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDA
QRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDN
GVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRAL
SSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEI
VLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDV
CPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLL
GTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIE
RMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE
EKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTNEEEAGEKDEL
NT seq 1968 nt   +upstreamnt  +downstreamnt
atgaagctctccctggtggctgcggtgctgctgctgctgctcggcatggcacgagcggag
gaggaggacaagaaggaggacgtgggcacggtggtcggcatcgacctgggcaccacctac
tcctgcgtcggggtgttcaagaacggtcgcgtggagatcatcgccaacgatcaaggcaac
cgcatcacgccgtcttatgtggccttcactcctgaaggggagcgtctgatcggcgatgca
gccaagaaccagctcacctccaatcctgagaacacagtcttcgacgccaagcgactcatt
ggccggacatggaacgacccttccgtgcagcaggacatcaagttcttacctttcaaggtg
gttgaaaagaaaactaaaccatacattcaagttgatgttggaggtggacaaacaaagaca
tttgctcctgaagaaatttctgccatggttctcactaaaatgaaggaaactgctgaggct
tatttgggaaagaaggttactcatgcagttgttactgtaccagcatatttcaatgatgcc
caacgccaggcaaccaaagatgctggcactattgctggattgaatgtcatgaggatcatc
aatgagcctacagcagctgctattgcttatggcctggataagagggaaggggagaagaac
atcctggtgtttgacctgggtggtggaaccttcgatgtgtctcttctcaccattgataat
ggtgtctttgaagtcgtggccactaatggagatactcacctgggtggagaagactttgac
cagcgtgtcatggaacacttcatcaagctctacaaaaagaagactggcaaagatgttcgg
aaagataacagagctgtgcagaaactccggcgtgaggtagaaaaggccaaacgggccctg
tcttcccaacatcaagccagaattgaaatagagtccttctatgaaggagaagacttctcg
gagaccctgactcgggccaaatttgaagagctaaacatggacctgttccgttccaccatg
aagcctgtccagaaagtgttggaagattctgatttaaagaagtctgatattgatgaaatt
gttcttgttggtggctctactagaatcccaaagattcaacagctggttaaagagtttttc
aatggcaaggagccatcccgaggcataaacccagatgaggctgtggcatatggggccgct
gtccaggctggtgtgctctctggtgatcaagatacaggtgatctggtgctgcttgatgta
tgtcccttgacacttggtattgaaaccgtgggaggtgtcatgaccaaactgattccacgg
aacactgtggtgcccaccaagaagtctcagatcttctctacagcctctgataatcaacca
actgttaccatcaaagtctatgaaggtgaacgacccctgacgaaagacaatcaccttctg
ggaacttttgatctgactggaattcctcctgcaccccgtggtgtcccacagattgaagtc
acctttgagatagatgtgaatggcattcttcgagtgacagctgaagacaaaggtacaggc
aacaaaaataagatcacaattaccaatgaccaaaatcgcctgacacctgaagaaattgaa
agaatggtcaatgatgctgagaagtttgctgaggaagacaaaaagctcaaggagcgcatt
gacacaagaaatgaattggaaagctatgcctactctcttaagaatcagattggagataaa
gaaaaactgggaggtaaactttcctcagaagataaggagaccatggaaaaggctgtagaa
gaaaagattgagtggctggaaagtcaccaagatgctgacattgaagatttcaaagctaaa
aagaaggagctagaagaaattgttcagccaattatcagcaaactctatggaagtgcaggc
ccccccccaaccaatgaggaggaagcaggagaaaaagatgagttgtag

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