KEGG   Muntiacus reevesi (Reeves' muntjac): 136168320
Entry
136168320         CDS       T10466                                 
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01521  EGFR tyrosine kinase inhibitor resistance
mree01522  Endocrine resistance
mree01524  Platinum drug resistance
mree04010  MAPK signaling pathway
mree04012  ErbB signaling pathway
mree04014  Ras signaling pathway
mree04015  Rap1 signaling pathway
mree04022  cGMP-PKG signaling pathway
mree04024  cAMP signaling pathway
mree04062  Chemokine signaling pathway
mree04066  HIF-1 signaling pathway
mree04068  FoxO signaling pathway
mree04071  Sphingolipid signaling pathway
mree04072  Phospholipase D signaling pathway
mree04140  Autophagy - animal
mree04150  mTOR signaling pathway
mree04151  PI3K-Akt signaling pathway
mree04152  AMPK signaling pathway
mree04210  Apoptosis
mree04211  Longevity regulating pathway
mree04213  Longevity regulating pathway - multiple species
mree04218  Cellular senescence
mree04261  Adrenergic signaling in cardiomyocytes
mree04370  VEGF signaling pathway
mree04371  Apelin signaling pathway
mree04380  Osteoclast differentiation
mree04510  Focal adhesion
mree04517  IgSF CAM signaling
mree04518  Integrin signaling
mree04550  Signaling pathways regulating pluripotency of stem cells
mree04611  Platelet activation
mree04613  Neutrophil extracellular trap formation
mree04620  Toll-like receptor signaling pathway
mree04625  C-type lectin receptor signaling pathway
mree04630  JAK-STAT signaling pathway
mree04660  T cell receptor signaling pathway
mree04662  B cell receptor signaling pathway
mree04664  Fc epsilon RI signaling pathway
mree04666  Fc gamma R-mediated phagosome formation
mree04668  TNF signaling pathway
mree04722  Neurotrophin signaling pathway
mree04725  Cholinergic synapse
mree04728  Dopaminergic synapse
mree04810  Regulation of actin cytoskeleton
mree04910  Insulin signaling pathway
mree04914  Progesterone-mediated oocyte maturation
mree04915  Estrogen signaling pathway
mree04917  Prolactin signaling pathway
mree04919  Thyroid hormone signaling pathway
mree04920  Adipocytokine signaling pathway
mree04922  Glucagon signaling pathway
mree04923  Regulation of lipolysis in adipocytes
mree04926  Relaxin signaling pathway
mree04929  GnRH secretion
mree04931  Insulin resistance
mree04932  Non-alcoholic fatty liver disease
mree04933  AGE-RAGE signaling pathway in diabetic complications
mree04935  Growth hormone synthesis, secretion and action
mree04936  Alcoholic liver disease
mree04973  Carbohydrate digestion and absorption
mree05010  Alzheimer disease
mree05017  Spinocerebellar ataxia
mree05132  Salmonella infection
mree05135  Yersinia infection
mree05142  Chagas disease
mree05145  Toxoplasmosis
mree05152  Tuberculosis
mree05160  Hepatitis C
mree05161  Hepatitis B
mree05162  Measles
mree05163  Human cytomegalovirus infection
mree05164  Influenza A
mree05165  Human papillomavirus infection
mree05166  Human T-cell leukemia virus 1 infection
mree05167  Kaposi sarcoma-associated herpesvirus infection
mree05168  Herpes simplex virus 1 infection
mree05169  Epstein-Barr virus infection
mree05170  Human immunodeficiency virus 1 infection
mree05200  Pathways in cancer
mree05205  Proteoglycans in cancer
mree05207  Chemical carcinogenesis - receptor activation
mree05208  Chemical carcinogenesis - reactive oxygen species
mree05210  Colorectal cancer
mree05211  Renal cell carcinoma
mree05212  Pancreatic cancer
mree05213  Endometrial cancer
mree05214  Glioma
mree05215  Prostate cancer
mree05218  Melanoma
mree05220  Chronic myeloid leukemia
mree05221  Acute myeloid leukemia
mree05222  Small cell lung cancer
mree05223  Non-small cell lung cancer
mree05224  Breast cancer
mree05225  Hepatocellular carcinoma
mree05226  Gastric cancer
mree05230  Central carbon metabolism in cancer
mree05231  Choline metabolism in cancer
mree05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mree05415  Diabetic cardiomyopathy
mree05417  Lipid and atherosclerosis
mree05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    136168320 (AKT3)
   04012 ErbB signaling pathway
    136168320 (AKT3)
   04014 Ras signaling pathway
    136168320 (AKT3)
   04015 Rap1 signaling pathway
    136168320 (AKT3)
   04370 VEGF signaling pathway
    136168320 (AKT3)
   04371 Apelin signaling pathway
    136168320 (AKT3)
   04630 JAK-STAT signaling pathway
    136168320 (AKT3)
   04668 TNF signaling pathway
    136168320 (AKT3)
   04066 HIF-1 signaling pathway
    136168320 (AKT3)
   04068 FoxO signaling pathway
    136168320 (AKT3)
   04072 Phospholipase D signaling pathway
    136168320 (AKT3)
   04071 Sphingolipid signaling pathway
    136168320 (AKT3)
   04024 cAMP signaling pathway
    136168320 (AKT3)
   04022 cGMP-PKG signaling pathway
    136168320 (AKT3)
   04151 PI3K-Akt signaling pathway
    136168320 (AKT3)
   04152 AMPK signaling pathway
    136168320 (AKT3)
   04150 mTOR signaling pathway
    136168320 (AKT3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    136168320 (AKT3)
   04518 Integrin signaling
    136168320 (AKT3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    136168320 (AKT3)
  09143 Cell growth and death
   04210 Apoptosis
    136168320 (AKT3)
   04218 Cellular senescence
    136168320 (AKT3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    136168320 (AKT3)
   04550 Signaling pathways regulating pluripotency of stem cells
    136168320 (AKT3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    136168320 (AKT3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    136168320 (AKT3)
   04613 Neutrophil extracellular trap formation
    136168320 (AKT3)
   04620 Toll-like receptor signaling pathway
    136168320 (AKT3)
   04625 C-type lectin receptor signaling pathway
    136168320 (AKT3)
   04660 T cell receptor signaling pathway
    136168320 (AKT3)
   04662 B cell receptor signaling pathway
    136168320 (AKT3)
   04664 Fc epsilon RI signaling pathway
    136168320 (AKT3)
   04666 Fc gamma R-mediated phagosome formation
    136168320 (AKT3)
   04062 Chemokine signaling pathway
    136168320 (AKT3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    136168320 (AKT3)
   04922 Glucagon signaling pathway
    136168320 (AKT3)
   04923 Regulation of lipolysis in adipocytes
    136168320 (AKT3)
   04920 Adipocytokine signaling pathway
    136168320 (AKT3)
   04929 GnRH secretion
    136168320 (AKT3)
   04915 Estrogen signaling pathway
    136168320 (AKT3)
   04914 Progesterone-mediated oocyte maturation
    136168320 (AKT3)
   04917 Prolactin signaling pathway
    136168320 (AKT3)
   04926 Relaxin signaling pathway
    136168320 (AKT3)
   04935 Growth hormone synthesis, secretion and action
    136168320 (AKT3)
   04919 Thyroid hormone signaling pathway
    136168320 (AKT3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    136168320 (AKT3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    136168320 (AKT3)
  09156 Nervous system
   04725 Cholinergic synapse
    136168320 (AKT3)
   04728 Dopaminergic synapse
    136168320 (AKT3)
   04722 Neurotrophin signaling pathway
    136168320 (AKT3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    136168320 (AKT3)
  09149 Aging
   04211 Longevity regulating pathway
    136168320 (AKT3)
   04213 Longevity regulating pathway - multiple species
    136168320 (AKT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136168320 (AKT3)
   05205 Proteoglycans in cancer
    136168320 (AKT3)
   05207 Chemical carcinogenesis - receptor activation
    136168320 (AKT3)
   05208 Chemical carcinogenesis - reactive oxygen species
    136168320 (AKT3)
   05230 Central carbon metabolism in cancer
    136168320 (AKT3)
   05231 Choline metabolism in cancer
    136168320 (AKT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136168320 (AKT3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    136168320 (AKT3)
   05212 Pancreatic cancer
    136168320 (AKT3)
   05225 Hepatocellular carcinoma
    136168320 (AKT3)
   05226 Gastric cancer
    136168320 (AKT3)
   05214 Glioma
    136168320 (AKT3)
   05221 Acute myeloid leukemia
    136168320 (AKT3)
   05220 Chronic myeloid leukemia
    136168320 (AKT3)
   05218 Melanoma
    136168320 (AKT3)
   05211 Renal cell carcinoma
    136168320 (AKT3)
   05215 Prostate cancer
    136168320 (AKT3)
   05213 Endometrial cancer
    136168320 (AKT3)
   05224 Breast cancer
    136168320 (AKT3)
   05222 Small cell lung cancer
    136168320 (AKT3)
   05223 Non-small cell lung cancer
    136168320 (AKT3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    136168320 (AKT3)
   05170 Human immunodeficiency virus 1 infection
    136168320 (AKT3)
   05161 Hepatitis B
    136168320 (AKT3)
   05160 Hepatitis C
    136168320 (AKT3)
   05164 Influenza A
    136168320 (AKT3)
   05162 Measles
    136168320 (AKT3)
   05168 Herpes simplex virus 1 infection
    136168320 (AKT3)
   05163 Human cytomegalovirus infection
    136168320 (AKT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136168320 (AKT3)
   05169 Epstein-Barr virus infection
    136168320 (AKT3)
   05165 Human papillomavirus infection
    136168320 (AKT3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136168320 (AKT3)
   05135 Yersinia infection
    136168320 (AKT3)
   05152 Tuberculosis
    136168320 (AKT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    136168320 (AKT3)
   05142 Chagas disease
    136168320 (AKT3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136168320 (AKT3)
   05017 Spinocerebellar ataxia
    136168320 (AKT3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136168320 (AKT3)
   05418 Fluid shear stress and atherosclerosis
    136168320 (AKT3)
   05415 Diabetic cardiomyopathy
    136168320 (AKT3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    136168320 (AKT3)
   04932 Non-alcoholic fatty liver disease
    136168320 (AKT3)
   04931 Insulin resistance
    136168320 (AKT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    136168320 (AKT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136168320 (AKT3)
   01524 Platinum drug resistance
    136168320 (AKT3)
   01522 Endocrine resistance
    136168320 (AKT3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mree01001]
    136168320 (AKT3)
Enzymes [BR:mree01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     136168320 (AKT3)
Protein kinases [BR:mree01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   136168320 (AKT3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1
Other DBs
NCBI-GeneID: 136168320
NCBI-ProteinID: XP_065791692
LinkDB
Position
5:79943597..80216670
AA seq 479 aa
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDEDGMDCMDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aactggaggccaagatatttccttttgaagacagatggctcattcataggatataaagag
aaaccccaagatgtggatttaccttatcccctcaacaacttttcagtagcaaaatgccag
ttaatgaaaacagaacgaccaaagccaaacacatttattatcagatgtctccagtggacc
actgttatagagagaacatttcacgtagatactccagaggaaagggaagaatggacagaa
gctatccaggctgtagcagacagactccagaggcaagaagaagagagaatgaattgtagt
ccaacttcacaaattgataatataggagaggaagagatggatgcttctacaacccatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacttttggg
aaagttattttggttcgagagaaggcaagtggaaaatattatgctatgaagattctgaag
aaagaagttattattgccaaggatgaagtggcacacactttaactgaaagcagagtatta
aagaacactagacatccctttttaacatccctgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagag
cgggtgttctccgaggaccgcacacgtttctatggtgcagaaattgtctctgccttggac
tatctacattccggaaagattgtgtaccgtgatctcaagttggagaatttgatgctggat
aaagatggccacataaaaatcacagattttggactttgcaaagaagggatcactgatgca
gccaccatgaagactttctgtggtacaccagagtatctggcaccagaggtattagaagat
aatgactatggccgagccgtggattggtggggccttggggttgtcatgtatgaaatgatg
tgcgggagattacctttctataaccaggatcatgagaaactttttgaactaattctaatg
gaagacattaaatttcctcgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggaggaccagatgatgcaaaagaaattatg
agacacagtttcttttctggagtaaactggcaagatgtgtatgataaaaagcttgtacct
ccttttaagcctcaagtaacgtctgagacagacaccagatattttgatgaagaatttaca
gctcagactattacaataacaccgcctgaaaaatatgatgaggacggtatggactgcatg
gacaatgagaggcggccgcacttccctcaattttcctactctgcaagtggacgagaataa

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