KEGG   Muntiacus reevesi (Reeves' muntjac): 136168397
Entry
136168397         CDS       T10466                                 
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree00562  Inositol phosphate metabolism
mree01100  Metabolic pathways
mree01521  EGFR tyrosine kinase inhibitor resistance
mree01522  Endocrine resistance
mree01524  Platinum drug resistance
mree04012  ErbB signaling pathway
mree04014  Ras signaling pathway
mree04015  Rap1 signaling pathway
mree04024  cAMP signaling pathway
mree04062  Chemokine signaling pathway
mree04066  HIF-1 signaling pathway
mree04068  FoxO signaling pathway
mree04070  Phosphatidylinositol signaling system
mree04071  Sphingolipid signaling pathway
mree04072  Phospholipase D signaling pathway
mree04081  Hormone signaling
mree04140  Autophagy - animal
mree04145  Phagocytosis
mree04150  mTOR signaling pathway
mree04151  PI3K-Akt signaling pathway
mree04152  AMPK signaling pathway
mree04210  Apoptosis
mree04211  Longevity regulating pathway
mree04213  Longevity regulating pathway - multiple species
mree04218  Cellular senescence
mree04360  Axon guidance
mree04370  VEGF signaling pathway
mree04380  Osteoclast differentiation
mree04510  Focal adhesion
mree04517  IgSF CAM signaling
mree04518  Integrin signaling
mree04550  Signaling pathways regulating pluripotency of stem cells
mree04611  Platelet activation
mree04613  Neutrophil extracellular trap formation
mree04620  Toll-like receptor signaling pathway
mree04625  C-type lectin receptor signaling pathway
mree04630  JAK-STAT signaling pathway
mree04650  Natural killer cell mediated cytotoxicity
mree04660  T cell receptor signaling pathway
mree04662  B cell receptor signaling pathway
mree04664  Fc epsilon RI signaling pathway
mree04666  Fc gamma R-mediated phagosome formation
mree04668  TNF signaling pathway
mree04670  Leukocyte transendothelial migration
mree04722  Neurotrophin signaling pathway
mree04725  Cholinergic synapse
mree04750  Inflammatory mediator regulation of TRP channels
mree04810  Regulation of actin cytoskeleton
mree04910  Insulin signaling pathway
mree04914  Progesterone-mediated oocyte maturation
mree04915  Estrogen signaling pathway
mree04917  Prolactin signaling pathway
mree04919  Thyroid hormone signaling pathway
mree04923  Regulation of lipolysis in adipocytes
mree04926  Relaxin signaling pathway
mree04929  GnRH secretion
mree04930  Type II diabetes mellitus
mree04931  Insulin resistance
mree04932  Non-alcoholic fatty liver disease
mree04933  AGE-RAGE signaling pathway in diabetic complications
mree04935  Growth hormone synthesis, secretion and action
mree04960  Aldosterone-regulated sodium reabsorption
mree04973  Carbohydrate digestion and absorption
mree05010  Alzheimer disease
mree05017  Spinocerebellar ataxia
mree05020  Prion disease
mree05100  Bacterial invasion of epithelial cells
mree05132  Salmonella infection
mree05135  Yersinia infection
mree05142  Chagas disease
mree05146  Amoebiasis
mree05160  Hepatitis C
mree05161  Hepatitis B
mree05162  Measles
mree05163  Human cytomegalovirus infection
mree05164  Influenza A
mree05165  Human papillomavirus infection
mree05166  Human T-cell leukemia virus 1 infection
mree05167  Kaposi sarcoma-associated herpesvirus infection
mree05168  Herpes simplex virus 1 infection
mree05169  Epstein-Barr virus infection
mree05170  Human immunodeficiency virus 1 infection
mree05171  Coronavirus disease
mree05200  Pathways in cancer
mree05203  Viral carcinogenesis
mree05205  Proteoglycans in cancer
mree05206  MicroRNAs in cancer
mree05207  Chemical carcinogenesis - receptor activation
mree05208  Chemical carcinogenesis - reactive oxygen species
mree05210  Colorectal cancer
mree05211  Renal cell carcinoma
mree05212  Pancreatic cancer
mree05213  Endometrial cancer
mree05214  Glioma
mree05215  Prostate cancer
mree05218  Melanoma
mree05220  Chronic myeloid leukemia
mree05221  Acute myeloid leukemia
mree05222  Small cell lung cancer
mree05223  Non-small cell lung cancer
mree05224  Breast cancer
mree05225  Hepatocellular carcinoma
mree05226  Gastric cancer
mree05230  Central carbon metabolism in cancer
mree05231  Choline metabolism in cancer
mree05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mree05415  Diabetic cardiomyopathy
mree05417  Lipid and atherosclerosis
mree05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mree00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    136168397 (PIK3CD)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    136168397 (PIK3CD)
   04014 Ras signaling pathway
    136168397 (PIK3CD)
   04015 Rap1 signaling pathway
    136168397 (PIK3CD)
   04370 VEGF signaling pathway
    136168397 (PIK3CD)
   04630 JAK-STAT signaling pathway
    136168397 (PIK3CD)
   04668 TNF signaling pathway
    136168397 (PIK3CD)
   04066 HIF-1 signaling pathway
    136168397 (PIK3CD)
   04068 FoxO signaling pathway
    136168397 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    136168397 (PIK3CD)
   04072 Phospholipase D signaling pathway
    136168397 (PIK3CD)
   04071 Sphingolipid signaling pathway
    136168397 (PIK3CD)
   04024 cAMP signaling pathway
    136168397 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    136168397 (PIK3CD)
   04152 AMPK signaling pathway
    136168397 (PIK3CD)
   04150 mTOR signaling pathway
    136168397 (PIK3CD)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    136168397 (PIK3CD)
   04517 IgSF CAM signaling
    136168397 (PIK3CD)
   04518 Integrin signaling
    136168397 (PIK3CD)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    136168397 (PIK3CD)
   04140 Autophagy - animal
    136168397 (PIK3CD)
  09143 Cell growth and death
   04210 Apoptosis
    136168397 (PIK3CD)
   04218 Cellular senescence
    136168397 (PIK3CD)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    136168397 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    136168397 (PIK3CD)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    136168397 (PIK3CD)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    136168397 (PIK3CD)
   04613 Neutrophil extracellular trap formation
    136168397 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    136168397 (PIK3CD)
   04625 C-type lectin receptor signaling pathway
    136168397 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    136168397 (PIK3CD)
   04660 T cell receptor signaling pathway
    136168397 (PIK3CD)
   04662 B cell receptor signaling pathway
    136168397 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    136168397 (PIK3CD)
   04666 Fc gamma R-mediated phagosome formation
    136168397 (PIK3CD)
   04670 Leukocyte transendothelial migration
    136168397 (PIK3CD)
   04062 Chemokine signaling pathway
    136168397 (PIK3CD)
  09152 Endocrine system
   04910 Insulin signaling pathway
    136168397 (PIK3CD)
   04923 Regulation of lipolysis in adipocytes
    136168397 (PIK3CD)
   04929 GnRH secretion
    136168397 (PIK3CD)
   04915 Estrogen signaling pathway
    136168397 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    136168397 (PIK3CD)
   04917 Prolactin signaling pathway
    136168397 (PIK3CD)
   04926 Relaxin signaling pathway
    136168397 (PIK3CD)
   04935 Growth hormone synthesis, secretion and action
    136168397 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    136168397 (PIK3CD)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    136168397 (PIK3CD)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    136168397 (PIK3CD)
  09156 Nervous system
   04725 Cholinergic synapse
    136168397 (PIK3CD)
   04722 Neurotrophin signaling pathway
    136168397 (PIK3CD)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    136168397 (PIK3CD)
  09158 Development and regeneration
   04360 Axon guidance
    136168397 (PIK3CD)
   04380 Osteoclast differentiation
    136168397 (PIK3CD)
  09149 Aging
   04211 Longevity regulating pathway
    136168397 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    136168397 (PIK3CD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136168397 (PIK3CD)
   05206 MicroRNAs in cancer
    136168397 (PIK3CD)
   05205 Proteoglycans in cancer
    136168397 (PIK3CD)
   05207 Chemical carcinogenesis - receptor activation
    136168397 (PIK3CD)
   05208 Chemical carcinogenesis - reactive oxygen species
    136168397 (PIK3CD)
   05203 Viral carcinogenesis
    136168397 (PIK3CD)
   05230 Central carbon metabolism in cancer
    136168397 (PIK3CD)
   05231 Choline metabolism in cancer
    136168397 (PIK3CD)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136168397 (PIK3CD)
  09162 Cancer: specific types
   05210 Colorectal cancer
    136168397 (PIK3CD)
   05212 Pancreatic cancer
    136168397 (PIK3CD)
   05225 Hepatocellular carcinoma
    136168397 (PIK3CD)
   05226 Gastric cancer
    136168397 (PIK3CD)
   05214 Glioma
    136168397 (PIK3CD)
   05221 Acute myeloid leukemia
    136168397 (PIK3CD)
   05220 Chronic myeloid leukemia
    136168397 (PIK3CD)
   05218 Melanoma
    136168397 (PIK3CD)
   05211 Renal cell carcinoma
    136168397 (PIK3CD)
   05215 Prostate cancer
    136168397 (PIK3CD)
   05213 Endometrial cancer
    136168397 (PIK3CD)
   05224 Breast cancer
    136168397 (PIK3CD)
   05222 Small cell lung cancer
    136168397 (PIK3CD)
   05223 Non-small cell lung cancer
    136168397 (PIK3CD)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    136168397 (PIK3CD)
   05170 Human immunodeficiency virus 1 infection
    136168397 (PIK3CD)
   05161 Hepatitis B
    136168397 (PIK3CD)
   05160 Hepatitis C
    136168397 (PIK3CD)
   05171 Coronavirus disease
    136168397 (PIK3CD)
   05164 Influenza A
    136168397 (PIK3CD)
   05162 Measles
    136168397 (PIK3CD)
   05168 Herpes simplex virus 1 infection
    136168397 (PIK3CD)
   05163 Human cytomegalovirus infection
    136168397 (PIK3CD)
   05167 Kaposi sarcoma-associated herpesvirus infection
    136168397 (PIK3CD)
   05169 Epstein-Barr virus infection
    136168397 (PIK3CD)
   05165 Human papillomavirus infection
    136168397 (PIK3CD)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    136168397 (PIK3CD)
   05135 Yersinia infection
    136168397 (PIK3CD)
   05100 Bacterial invasion of epithelial cells
    136168397 (PIK3CD)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    136168397 (PIK3CD)
   05142 Chagas disease
    136168397 (PIK3CD)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    136168397 (PIK3CD)
   05017 Spinocerebellar ataxia
    136168397 (PIK3CD)
   05020 Prion disease
    136168397 (PIK3CD)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    136168397 (PIK3CD)
   05418 Fluid shear stress and atherosclerosis
    136168397 (PIK3CD)
   05415 Diabetic cardiomyopathy
    136168397 (PIK3CD)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    136168397 (PIK3CD)
   04932 Non-alcoholic fatty liver disease
    136168397 (PIK3CD)
   04931 Insulin resistance
    136168397 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    136168397 (PIK3CD)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136168397 (PIK3CD)
   01524 Platinum drug resistance
    136168397 (PIK3CD)
   01522 Endocrine resistance
    136168397 (PIK3CD)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mree04131]
    136168397 (PIK3CD)
Enzymes [BR:mree01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     136168397 (PIK3CD)
Membrane trafficking [BR:mree04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    136168397 (PIK3CD)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_p85B PI3K_rbd PI3K_C2
Other DBs
NCBI-GeneID: 136168397
NCBI-ProteinID: XP_065791871
LinkDB
Position
5:complement(89958799..90020328)
AA seq 1044 aa
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINVCDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
SLRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDVVKVSSQKTTKPQTKELMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGAVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt   +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagaacgtg
gcagttgatttcttgctgcccacaggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcactatcaagaaggtgttatggcaccgcgcccagtacgagccgctcttccac
atgctcagtgaccctgaggcctacgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctctgcgacatccagcccttcctgcccgtcctgagg
ctggtggcccgcgagggtgaccgcgtgaagaagctcatcaactcgcagatcagcctgctc
atcggcaaaggcctccacgagtttgactctttgcaagacccggaggtgaatgacttccga
ggcaagatgcgccagttctgcgaggaggcggctgcccgcaggcagcagctgggctgggag
gcctggctgcagtacagcttccctctgcagttggagccctcagcgcggagctgggggccg
ggcaccctgcgcgtccccaatcgggccctcctggtcaatgtcaagtttgagggcagcgag
gagagcttcaccttccaggtgtccaccaaggatgtgcccctggcactgatggcctgtgcc
ctccgaaagaaggccacagtgttccggcagccgctggtggagcagcctgaggactacaca
ctgcaggtgaacggcaagcacgagtacctgtacggcagctaccccctctgccagttccag
tacatctgcagctgcctgcacagcggactgaccccccacctgactatggtgcactcctcc
tccatcctcgcaatgcgggacgagcagagcaaccctgccccccaagtccagaagccacgc
accaaaccgccccccatccccatgaagaagccctcctccgtgtccctctggtccctggag
cagcctttctacatcgagctgatccagggcagcaaagtgaatgctgacgagcggatgaag
ctggtggtgcaggctgggctcttccacggcaacgagacgctatgcaagacggtgtccagc
tcggaggtgagtgtgtgctcggagcccgtgtggaagcagcggctggagtttgacatcaac
gtctgtgacctgccccgcatggcccggctctgcttcgcactttacgccgtgattgagaag
gctaagaaggcccgctccaccaagaagaagtccaagaaggcggactgccccattgcctgg
gccaacctcatgctgtttgactacaaggaccagctgaagacgggcgagcgctgtctctac
atgtggccctctgtcccagacgagaaaggggagctactgaacccctgtggcaccgtgcgg
agtaaccccaacactgagagtgcggccgccctggtcatctttcttcccgaggtggcccct
caccctgtatactacccttccctggacaagatcctggagctggggcggctcggagagcac
ggacgcttcacggaggaggagcagctgcagctgcgggagatcctggagcgccggggttcc
ggggaactgtatgagcatgagaaggacctggtgtggaagatgcggcacgagatccaggag
cactttcccgaggcccttgcccggctgctgctggtcactaagtggaacaaacacgaggac
gtggcccagatgctctacctgctctgctcctggcctgaactgccagtcctgagcgccctg
gagttgctagacttcagcttccccgaccgccacgtgggctccttcgccatcaagtccctg
cggaaactgacggacgacgagcttttccagtacctgctgcagctggtgcaggtgctcaag
tacgagtcctacctcgactgcgagctgaccaaattcctgctggaccgggccctggccaat
cgcaggatcggccacttcctcttctggcacctccgctccgagatgcacgtgccgtcggtg
tccctgcgcttcggcctgatcatggaagcctactgccggggcagcacccaccacatgaag
gtgctgatgaagcagggggaagcactgagcaaactgaaagccctgaatgacgtcgtcaaa
gtgagctcccagaagaccaccaagccccagaccaaggagctgatgcacctgtgtatgcgc
caggagacctacctggaggccctgtcccacttgcagtccccactcgaccccagcaccctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaagcccctgtgg
gtcatgtacagcaacgaggaggcgggcagcgatggcgctgtgggcatcatctttaagaat
ggggatgacctccgccaggacatgctgaccctgcagatgatccagctcatggacattctg
tggaagcaggaaggcttggacctgaggatgaccccctacggctgcctctccactggggac
cgcacgggcctcatcgaggtggtgcttcactcggacaccattgccaacatccagctgaac
aagagcaacatggcggccacggccgccttcaataaggatgctctgctcaactggctcaag
tccaagaaccctggggaggccctggatcgagccattgaggagttcaccctctcctgtgct
ggctactgtgtggccacctatgtgctgggcattggcgatcgccatagcgacaacatcatg
atccgagagaacgggcagctgttccacattgatttcggccactttctggggaacttcaag
accaagtttggaatcaaccgtgagcgggtcccgttcatcctcacctatgactttgtccac
gtgatccagcaggggaagacaaataatagtgagaagtttgaaaggttccggggctactgt
gagcgggcctacaccatcctgcggcgccatgggctccttttcctccacctctttgccctg
atgcgggcggcaggcctgcctgagctcagttgctccaaagacatccagtatctcaaggat
tctctggcattggggaaaacagaggaggaagctctgaagcacttccgagtgaagtttaat
gaagccctccgggagagctggaaaaccaaagtgaactggctggcccacaatgtgtccaaa
gataacaggcaataa

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