KEGG   Muntiacus reevesi (Reeves' muntjac): 136169799
Entry
136169799         CDS       T10466                                 
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
mree  Muntiacus reevesi (Reeves' muntjac)
Pathway
mree01521  EGFR tyrosine kinase inhibitor resistance
mree01522  Endocrine resistance
mree04012  ErbB signaling pathway
mree04066  HIF-1 signaling pathway
mree04140  Autophagy - animal
mree04150  mTOR signaling pathway
mree04151  PI3K-Akt signaling pathway
mree04152  AMPK signaling pathway
mree04211  Longevity regulating pathway
mree04213  Longevity regulating pathway - multiple species
mree04350  TGF-beta signaling pathway
mree04371  Apelin signaling pathway
mree04666  Fc gamma R-mediated phagocytosis
mree04714  Thermogenesis
mree04910  Insulin signaling pathway
mree04931  Insulin resistance
mree05163  Human cytomegalovirus infection
mree05165  Human papillomavirus infection
mree05170  Human immunodeficiency virus 1 infection
mree05200  Pathways in cancer
mree05205  Proteoglycans in cancer
mree05207  Chemical carcinogenesis - receptor activation
mree05210  Colorectal cancer
mree05212  Pancreatic cancer
mree05221  Acute myeloid leukemia
mree05224  Breast cancer
mree05225  Hepatocellular carcinoma
mree05226  Gastric cancer
mree05231  Choline metabolism in cancer
mree05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mree00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    136169799 (RPS6KB2)
   04350 TGF-beta signaling pathway
    136169799 (RPS6KB2)
   04371 Apelin signaling pathway
    136169799 (RPS6KB2)
   04066 HIF-1 signaling pathway
    136169799 (RPS6KB2)
   04151 PI3K-Akt signaling pathway
    136169799 (RPS6KB2)
   04152 AMPK signaling pathway
    136169799 (RPS6KB2)
   04150 mTOR signaling pathway
    136169799 (RPS6KB2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    136169799 (RPS6KB2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    136169799 (RPS6KB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    136169799 (RPS6KB2)
  09149 Aging
   04211 Longevity regulating pathway
    136169799 (RPS6KB2)
   04213 Longevity regulating pathway - multiple species
    136169799 (RPS6KB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    136169799 (RPS6KB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    136169799 (RPS6KB2)
   05205 Proteoglycans in cancer
    136169799 (RPS6KB2)
   05207 Chemical carcinogenesis - receptor activation
    136169799 (RPS6KB2)
   05231 Choline metabolism in cancer
    136169799 (RPS6KB2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    136169799 (RPS6KB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    136169799 (RPS6KB2)
   05212 Pancreatic cancer
    136169799 (RPS6KB2)
   05225 Hepatocellular carcinoma
    136169799 (RPS6KB2)
   05226 Gastric cancer
    136169799 (RPS6KB2)
   05221 Acute myeloid leukemia
    136169799 (RPS6KB2)
   05224 Breast cancer
    136169799 (RPS6KB2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    136169799 (RPS6KB2)
   05163 Human cytomegalovirus infection
    136169799 (RPS6KB2)
   05165 Human papillomavirus infection
    136169799 (RPS6KB2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    136169799 (RPS6KB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    136169799 (RPS6KB2)
   01522 Endocrine resistance
    136169799 (RPS6KB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mree01001]
    136169799 (RPS6KB2)
Enzymes [BR:mree01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     136169799 (RPS6KB2)
Protein kinases [BR:mree01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   136169799 (RPS6KB2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7 FeoB_C
Other DBs
NCBI-GeneID: 136169799
NCBI-ProteinID: XP_065793966
LinkDB
Position
5:43047902..43053764
AA seq 485 aa
MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTESSVNPGPE
RIGPHCFELLRVLGKGNYGKVFQVRKVQGSNLGKIYAMKVLRKAKIVRNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLSEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGTVTHTFCGTIEYMAPEI
LVRSGHSRAVDWWSLGALMHDMLTGSPPFTAENRKKTMDKIIRGKLELPPYLTPDARDLV
KKFLKRNPNQRIGGGPGDAADVQRHPFFRHVNWDDLLARRVDPPFRPSLQSEEDVSQFDS
HFTRQTPVDSPDDTTLSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT
PISPLKFSPFEGFQPSPGPQELVEPPLPPLLPPPPPPPPPSTAPLPIRPPSGTKKSRRGR
GRPGR
NT seq 1458 nt   +upstreamnt  +downstreamnt
atggcggcggtgtttgacctggacctggagacagaggaaggcagcgaaggcgagggcgag
ccagagctcagccccgcggacgcgtgtcccctcgcggagttgagggcggctggcctggag
cctgtgggacactatgaggaggtggagctgactgagagcagtgtgaacccgggccctgag
cgcatcggtccccactgctttgagctgctgcgtgtgctgggcaaggggaactatggcaag
gtgttccaggtgcgaaaggtacagggcagcaatctgggcaaaatatatgccatgaaagtc
ctgaggaaggccaaaattgtgcgcaatgccaaggacacggcacacacgcgggctgagcgg
aacattctggagtcggtgaagcaccccttcattgtggaactggcctacgccttccagact
ggcggcaaactttacctcatccttgagtgcctcagcggcggtgagcttttcacgcacctg
gagcgagaaggcatcttcctagaagacacggcctgtttctacctgtcagagatcacactg
gccctgggccatctccactcccaaggcatcatctaccgggacctcaaacctgaaaacatc
atgctcaacagccagggccacatcaaactcacggactttggcctctgcaaggagtcgatc
cacgagggcaccgtgacccacaccttctgcggcaccatcgagtacatggcccccgagatt
ctggtgcgcagcggccacagccgggcggtggactggtggagcttgggggccctgatgcac
gacatgctcactggatcgccgcccttcactgcagagaatcggaagaaaaccatggacaag
atcatcagagggaagctggagctgcccccctacctcaccccggacgcccgggatcttgtc
aaaaagtttctgaagcggaatcctaaccagcggattggagggggccctggggatgctgct
gatgtgcagaggcaccccttcttccggcacgttaattgggatgacctcctggcccgccgt
gtggacccccctttccggccttccctgcagtcggaggaggacgtgagccagtttgactcc
cacttcacgaggcagacgccggtggacagtccagacgacacgacgctgagtgagagcgcc
aaccaggccttcctgggcttcacgtacgtggcgccctcggtcctggacagcatcaaggag
ggcttctccttccagcccaagctgcgctcccccaggcgcctcaacagcagcccccggacc
cccatcagccccctgaagttctcgcccttcgaggggttccagcccagccctggcccacag
gagctcgtggagcccccactgcctcccctgctgcctccaccaccgccgccaccgcccccg
agcaccgcccccctccccatccgacccccctcagggaccaagaagtccaggaggggccgc
gggcgccctgggcgctaa

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