Microbacterium resistens: K8F61_02465
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Entry
K8F61_02465 CDS
T07900
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mrn
Microbacterium resistens
Pathway
mrn00300
Lysine biosynthesis
mrn00550
Peptidoglycan biosynthesis
mrn01100
Metabolic pathways
mrn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mrn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
K8F61_02465
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
K8F61_02465
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
K8F61_02465
Enzymes [BR:
mrn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
K8F61_02465
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiA
Motif
Other DBs
NCBI-ProteinID:
UGS27095
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Position
528152..529576
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AA seq
474 aa
AA seq
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MIALSLGEIAALVGGELHPAADATPETVVSGAVDTDSRQIVEGGIFVAKPGEVTDGHRFV
GAARERGAVLALVERRVDEPISQIVVPDVVDAIAELARAVVARVRAAGDLRIVGVTGSNG
KTTTKNFLARILSDEGETVAPVASFNNEVGAPLTMLRVTPTTRFLVCEFGASAPGEIARL
AGLVEPDVVIVLMVGLAHAGGFGGIEETARAKAELVAAARRGGTAVLNLDDARVAAMRGA
ARERGLTVRGFGTGPGADVRAVDVDVDASGTTCTVVLAGDDGEQRLPLRLQVLGAHHVGN
ALAAITAAAALGVVPGDAVRRLETVEIAERWRMQPMGNDEVRIINDAYNASPDSMAAALR
TLAQITRPGERTVAVLGAMSELGEAAGDEHDRIGLLAVRLNIQRIVVVGAGARRLYLAAV
GEGSWDGEAVHLPDADAAYDYLREELRPGDRVLVKSSNSAGLRFLGDRLGESFS
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccctgtccctcggtgagatcgccgccctcgtcggcggtgagctgcatcccgcg
gccgacgcgaccccggagaccgtcgtctccggcgcggtcgacacggactcgcgacagatc
gtcgagggcgggatcttcgtcgccaagcccggcgaggtgaccgacgggcaccggttcgtc
ggcgcggcgcgcgagcgcggcgccgtgctggccctcgtcgagcggcgggtcgacgagccg
atctcccagatcgtcgttcccgacgtcgtcgacgcgatcgcggagctggcgcgggcggtc
gtcgccagggtccgtgcggcgggagacctccgcatcgtgggcgtcaccggctcgaacggc
aagaccacgaccaagaacttcctcgccaggatcctctccgacgagggcgagaccgtcgcg
cccgtcgcctcgttcaacaacgaggtcggcgctccgctcacgatgcttcgggtgacgccc
acgacccgcttcctcgtctgcgagttcggcgccagcgcgcccggggagatcgcgcgtctg
gcgggcctggtcgagccggacgtcgtcatcgtgctcatggtcggcctcgctcacgccggc
gggttcggcgggatcgaggagacggcgcgcgcgaaggccgagctggtcgccgcggcgcgc
cgcggcgggaccgccgtcctcaacctggacgacgctcgcgtcgccgcgatgcgcggtgcc
gcccgggagcgcgggctgaccgtccgcggcttcggcacggggccgggcgccgacgtgcgc
gcggtcgacgtggacgtcgacgcgagcgggacgacgtgcaccgtcgtcctcgccggagac
gacggcgaacagcgccttccgctgcgcctgcaggtcctcggcgcccaccacgtcggcaac
gccctcgccgcgatcaccgccgctgccgcgctcggggtggtcccgggcgacgcggtccgc
cgtctcgagacggtcgagatcgccgagcggtggcggatgcagccgatgggcaatgacgag
gtccgcatcatcaacgacgcgtacaacgccagcccggactccatggccgccgccctgcgc
acactggcgcagatcacgcggccgggggagcgcaccgtcgcggttctcggcgccatgagc
gagctgggggaggccgccggcgacgagcacgaccgcatcggcctgctcgccgtgcgtctg
aacatccagcgcatcgtcgttgtcggcgccggtgcccgcaggctgtacctcgccgcggtc
ggcgaggggtcgtgggacggggaggccgtgcacctgccggatgcggacgccgcgtacgac
tacctccgtgaggagctgcgccccggcgaccgcgtcctggtcaagtcgtccaactccgcc
gggctccggttcctcggcgaccgtctgggagaatcgttctcgtga
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