Methylomonas rapida: NM686_018845
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Entry
NM686_018845 CDS
T08781
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
mrp
Methylomonas rapida
Pathway
mrp00290
Valine, leucine and isoleucine biosynthesis
mrp00660
C5-Branched dibasic acid metabolism
mrp01100
Metabolic pathways
mrp01110
Biosynthesis of secondary metabolites
mrp01210
2-Oxocarboxylic acid metabolism
mrp01230
Biosynthesis of amino acids
Module
mrp_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
mrp_M00535
Isoleucine biosynthesis, pyruvate => 2-oxobutanoate
Brite
KEGG Orthology (KO) [BR:
mrp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NM686_018845 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NM686_018845 (leuB)
Enzymes [BR:
mrp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
NM686_018845 (leuB)
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Motif
Pfam:
Iso_dh
DUF6259
DUF2563
Cytochrom_B559a
Gp44-like_2nd
DUF166
Motif
Other DBs
NCBI-ProteinID:
WAR44390
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Position
3992815..3993945
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AA seq
376 aa
AA seq
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MAKKIAVLPGDGIGPEIVAEALKILSFLNTDMNLDLVFENALIGGAAYDAFGTPLPQITL
NLCKNADAVLLGAVGGPKWEPLPHAVRPERGLLSIRSELNLFSNLRPAILCPQLVDASTL
KPEVVSGLDIMIVRELTGGIYFGQPRGIRLLENGEQQGYNTLVYSESEIRRIAHSAFKTA
QKRHKKLCSVDKANVLEVTELWRNVMTEVGKDYPDVQLTHMYVDNAAMQLVRAPKQFDVI
VTTNMFGDILSDIAAMLTGSIGMLPSASLDASGKGMYEPIHGSAPDIAGKGIANPLATIL
SVAMMLRYTFNQPAAADRIEQAVNAALDAQVRTADIHSEGMVKVSTSEMGDTVLDALRRQ
SRQTSLQMHDSQSVGV
NT seq
1131 nt
NT seq
+upstream
nt +downstream
nt
atggctaaaaaaattgcagttttgccgggtgacgggattggccccgagattgtcgccgag
gccctcaagattttgagctttttgaataccgatatgaatctggatctggtattcgagaac
gcgctgatcggtggcgccgcatacgacgctttcggtacgccgctgccgcaaatcacgcta
aacctgtgcaaaaacgccgatgcggttttactgggcgcggtgggcgggccgaaatgggaa
cctttgcctcatgcggtgcgcccagaacgcggtttgttgagcatacgctcggagctaaac
ctgttttcgaatctgcgtccggcgattctatgtccgcagttagtcgatgcctctaccttg
aaacccgaagtcgtgtccgggctggacatcatgatcgtgcgcgaattgaccggcggtatc
tatttcggtcaaccgcgcggcattcgcctattggaaaatggcgaacagcaaggctacaac
acgctggtttatagcgaatcagaaattcgccgtattgctcattcggccttcaaaaccgcg
caaaaacgccataaaaagctctgttcggtagataaggccaatgtactggaagtcaccgaa
ctgtggcgcaatgtaatgaccgaagtcggcaaggactatccggacgtgcagctcactcac
atgtatgtcgacaatgccgcgatgcaactggtccgtgcgccgaaacagttcgacgtgatc
gtcacgaccaatatgttcggcgacatcctgtcggacatcgccgcgatgctgaccggctcg
atcggcatgctgccgtcggcttcgctggatgccagcggcaaaggcatgtacgagcctatc
cacggttcggcgccagatattgccggcaaaggcatcgccaacccgctggctaccattctg
tcggttgcgatgatgctgcgctacaccttcaatcagcccgcagccgctgatcgcatcgaa
caagccgtcaacgctgcattggatgcacaagtcagaacggcggatattcattctgagggc
atggtcaaagtcagcacctcggaaatgggcgatactgtgctcgatgcattgcgccgccag
tcacggcaaaccagccttcaaatgcatgattcccaatcggtcggagtttaa
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