Mucilaginibacter rubeus: DEO27_025100
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Entry
DEO27_025100 CDS
T06362
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
mrub
Mucilaginibacter rubeus
Pathway
mrub00260
Glycine, serine and threonine metabolism
mrub00261
Monobactam biosynthesis
mrub00270
Cysteine and methionine metabolism
mrub00300
Lysine biosynthesis
mrub01100
Metabolic pathways
mrub01110
Biosynthesis of secondary metabolites
mrub01120
Microbial metabolism in diverse environments
mrub01230
Biosynthesis of amino acids
Module
mrub_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
mrub00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
DEO27_025100 (thrA)
00270 Cysteine and methionine metabolism
DEO27_025100 (thrA)
00300 Lysine biosynthesis
DEO27_025100 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
DEO27_025100 (thrA)
Enzymes [BR:
mrub01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
DEO27_025100 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
DEO27_025100 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
ACT_7
ACT
NAD_binding_3
MotA_activ
Motif
Other DBs
NCBI-ProteinID:
QEM13148
UniProt:
A0A5C1I6L9
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All DBs
Position
6255607..6258057
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AA seq
816 aa
AA seq
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MKVLKFGGTSVGSAASIQTLLSILKDEVKNEEKPVVVLSAMGGVTNLLSAMAEDAANGKE
FTAGLAELEKRHFDTVKALLDVQNQNPALTRLKIHFNQLEELLQGVLTLRELTPKTRDQV
LAFGERCSTLMVSKVAAQHFGDVLFVDAADVIKTDSAFGNAKVNTELTERLVQGLYAENK
GKTLIVTGFIASNDAGQTTTLGRGGSDYTAAIFGAALNAQEIQIWTDVNGMMTADPRMVK
KAFSLTELTYTEAMELSYFGAKVIYPPTMIPAFLKKIPIVIKNTFEPEFAGTVIRHDCKA
STLPIKGISSINNISILNLEGSGMVGKSGFSGRLFSLLAREQINVILITQSSSEHSITFA
VQPQDTEKAKQVIEQEFELELAAKKLEHLVIEKNLAILAIVGENMKQTPGMSGKLFHALG
RNGVNVRAIAQGSSEYNISVIISANDLSKALNAVHDAFFVQLTKTLHAFCLGTGNIGKTM
FNQLNAHSEYLKDNNGIQVKIAGISNTRKMTFNSDGISLDTWQDDLQASPYEADLQSFIN
RMKEMNLPNCVFIDNTASPVPIGFYEEVFKANISVITCNKIGNSGSYQQYRTFKDTARAH
GVDFFYETNVGAGLPIINTLKNLMNSGDRVQRIEAILSGTISFIFNNFKGDANFHDVVKE
AQDKGYTEPDPRDDLSGKDFMRKMLILARDAGYALEESDVEIESVLPKASLEAKSVEDFY
ATLKTEDAHFAKLKDAAEKDGKVLRYIGKLEDGKVSITLQMVDENHPFYMLSGSDNIISF
TTDRYRERPLVVKGPGAGAEVTAAGVFADLINVGAN
NT seq
2451 nt
NT seq
+upstream
nt +downstream
nt
atgaaagttttaaaattcggaggtacttccgttggatcggcagccagtatccaaaccctg
ttaagcatcctgaaggatgaagtaaaaaatgaagagaagccggtggtagtattatctgcc
atgggcggcgtaaccaacctgctttcggctatggccgaagacgcggcaaacggtaaagag
ttcaccgccggtttggccgaattggaaaaacgccactttgatacggtaaaagcccttttg
gatgttcaaaaccaaaacccggcgcttacccgtttaaaaattcacttcaaccaactggaa
gaacttttacagggcgtgcttactcttcgcgaacttaccccgaaaacgcgcgatcaggtg
ctggccttcggtgagcgctgctcaacccttatggtgagcaaagttgccgcccagcatttt
ggcgatgtactgtttgttgatgctgccgacgtgatcaaaaccgacagcgctttcggcaat
gccaaggtaaacaccgagcttaccgaaagactggtacagggcctgtatgccgaaaataaa
ggcaaaacattaatcgttaccggtttcatcgcctcaaacgatgccgggcaaaccacaact
ttaggtcgcggtggttctgactataccgctgccatttttggcgcggcactaaacgcgcag
gaaatccagatctggacagatgttaacggcatgatgaccgccgatccgcgcatggttaaa
aaagcgttctctttaaccgagcttacttataccgaagctatggagctttcttacttcggt
gccaaggtgatctatccgccaaccatgatcccggcgttcttaaagaagatccctatcgtt
atcaaaaacacttttgagcccgagtttgcaggtaccgtaatccgtcatgattgcaaggcc
tctaccctgccaattaaaggtatttcatctatcaacaatattagcatcctcaatttagaa
ggtagcggcatggtaggcaaatcgggctttagcggccgcttattctccctgcttgcccgc
gagcagatcaacgtgatcctgatcacccaatcatcatctgagcatagcatcacctttgct
gttcagccacaggataccgaaaaggctaaacaagtcatagagcaggagtttgaactggaa
cttgccgccaaaaaactggagcatttagtaatcgaaaaaaatctggctatcctggctatc
gtaggcgaaaacatgaaacaaacgcctggcatgtcgggcaaattgttccatgcgcttggc
cgtaatggtgttaacgtaagggctattgctcagggctcgtcagaatataatatctcggtg
atcatctcggccaacgatttatcaaaagccttgaacgccgtacatgacgctttcttcgtg
cagcttaccaaaaccctgcacgcgttttgcctgggcaccggcaacatcggcaaaactatg
tttaaccagcttaacgcccacagcgagtatctgaaagacaataacggcatccaggttaaa
atagccggtatcagcaatacccgcaaaatgacattcaacagtgatggtatttcgttagat
acctggcaggatgatttgcaggcatctccttatgaggccgatctgcaatcattcatcaac
cgtatgaaagaaatgaacctgccaaactgtgtgtttatcgacaacactgcaagcccggtt
ccgattggtttttacgaagaggtttttaaagccaatatctcggtgatcacttgtaataaa
ataggcaactctggcagctatcagcaataccgtacatttaaggataccgcccgcgcccat
ggcgtcgatttcttttatgaaaccaatgttggtgccggtctgccaatcatcaataccctt
aaaaacctaatgaacagcggcgacagggtgcaacgcattgaagcaatactttcgggcact
atatcgttcatctttaataactttaagggtgatgccaatttccacgatgtggtaaaagag
gcgcaagacaagggctataccgaaccagatccgcgcgacgacctgagcggaaaggatttt
atgcgcaaaatgctcatccttgcccgcgatgccggttatgcgctcgaagaaagtgatgta
gaaattgaaagcgtactgccaaaagcaagtctggaagcaaaaagcgttgaagatttttac
gcgacactaaaaactgaagatgcgcattttgccaaactaaaagatgcagccgaaaaagac
ggcaaagtattacgctatattggtaaactggaggatggcaaagtaagcatcaccctgcaa
atggttgatgaaaaccatccgttctacatgctgtcgggcagtgataacatcatatccttc
actaccgacaggtatcgcgagcgcccactagttgtaaaaggccctggcgcaggtgccgaa
gtaaccgccgccggcgtatttgctgatttaataaacgtgggtgcaaattaa
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