Mycobacterium sp. JS623: Mycsm_00180
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Entry
Mycsm_00180 CDS
T02423
Name
(GenBank) acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II
KO
K15868
bile acid-coenzyme A ligase [EC:
6.2.1.7
]
Organism
msa
Mycobacterium sp. JS623
Pathway
msa00121
Secondary bile acid biosynthesis
Brite
KEGG Orthology (KO) [BR:
msa00001
]
09100 Metabolism
09103 Lipid metabolism
00121 Secondary bile acid biosynthesis
Mycsm_00180
Enzymes [BR:
msa01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.7 cholate---CoA ligase
Mycsm_00180
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Gene cluster
GFIT
Motif
Pfam:
AMP-binding
AMP-binding_C
Motif
Other DBs
NCBI-ProteinID:
AGB20641
UniProt:
L0IQZ3
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All DBs
Position
complement(185935..187404)
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AA seq
489 aa
AA seq
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MTAPIPSIGAEFSRLAGLSPDEAAVTCEGRTLTRAELDKSTNRLARAYAELGVHQGDYVT
IVLPNSIEWIQAALAVWKLGAVPQPLSARLPDAELEGLLELKPRALLVGRDDPRGVIPSV
PGDFTGDAGLSDAPLPEVVSPSWKALGSGGSTGRPKLIEAGGDSRFPGALAGYGMGAAEG
DIQLIAVPLSHNTGMTTATIGLLMRHHLVMMPRFDPAEFLRLIGEHRVSFMVVVPTIMQR
LLPVYRANPDAYDLSSVRRLWHVGAACPPAVKEAWIEILGPEAVWELYGGTELQALTFIS
GTQWLEHRGSVGVVVAGEMKVLDDDGNECPLGVVGEIYMRPAPGSAPTYRYVGAKAKSRD
GWDSLGDLGYFDQDRFLYLNDRRVDMFTVGGRNVYPAEIESALSAHPNVLSCLAVGVPDD
DLGQVPYVIVQADGLDEADVIAFLSERIASYKVPRTVEFSETPLRDDAGKARRSAVRDEI
IARRAQARS
NT seq
1470 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcacccatcccgtcgatcggtgcggagttctcacggctggccgggctgtccccg
gacgaggccgccgtcacctgcgaggggcgcacgctgacccgggcagaactcgacaagtcc
accaaccggctggcgcgcgcctacgcggaacttggtgtgcaccagggtgactacgtgacc
atcgtgctgccgaactcgatcgaatggatccaggccgcgctggccgtgtggaagctcggc
gcggtgccccagccgttgtcggcgcggctgcccgacgccgaactcgagggtctgctcgag
ctcaagccacgtgcgctgctggtgggccgcgacgacccgcgcggggtgatccccagtgtg
ccaggcgatttcaccggtgacgccggcttgtccgacgcgccgttaccggaggtggtgtcg
ccgagctggaaggcgctcggctcgggcggcagcaccggtcggcccaagctgatcgaggcg
ggcggcgacagccggtttcccggcgcgctggccggctacggaatgggtgccgccgaaggc
gacattcaactgatcgcggtgccgttgagtcacaacaccggcatgaccaccgcgacgatc
ggcttgttgatgcgtcaccatctggtgatgatgccgcgcttcgaccccgccgagtttctg
cggctgattggcgaacaccgggtcagcttcatggtggtggtgccgacgatcatgcagcgg
ctgcttcccgtgtatcgcgccaacccggacgcctacgacctgtcatcggttcggcggctg
tggcacgtcggcgcggcgtgtccgcccgcggtcaaggaagcgtggatcgagatactcggg
ccggaagcagtgtgggagttgtacgggggcaccgaacttcaggccttgacgttcatcagc
ggcacgcaatggctcgagcatcgcggctcggtcggggttgtcgttgcgggtgagatgaag
gtgctcgacgacgacggtaatgagtgcccgctcggcgtggttggtgagatttacatgcgg
ccggcgccgggtagcgcgccgacgtaccgttacgtcggcgccaaggccaagagccgcgac
ggatgggactcgctcggcgatctgggctacttcgatcaggaccgcttcctgtatctcaat
gaccggcgcgtggacatgttcaccgtcggcggccgcaacgtctaccccgccgaaatcgaa
tcagcattgtcagcccacccgaatgtgttgtcgtgcttggctgttggcgttccggacgat
gaccttggccaggtgccgtatgtcattgtgcaggccgacgggctcgacgaggcagacgtc
atcgcgttcctgtccgagcgcatcgcgtcctacaaggtgccccgcactgtggagttcagc
gagacgccgttgcgcgacgatgcgggcaaggcccgccgctcggcggtgcgcgacgaaatc
attgcgcggcgggctcaggcacgttcctga
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