Mycobacterium sp. JS623: Mycsm_02242
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Entry
Mycsm_02242 CDS
T02423
Name
(GenBank) acetolactate synthase, large subunit
KO
K01652
acetolactate synthase I/II/III large subunit [EC:
2.2.1.6
]
Organism
msa
Mycobacterium sp. JS623
Pathway
msa00290
Valine, leucine and isoleucine biosynthesis
msa00650
Butanoate metabolism
msa00660
C5-Branched dibasic acid metabolism
msa00770
Pantothenate and CoA biosynthesis
msa01100
Metabolic pathways
msa01110
Biosynthesis of secondary metabolites
msa01210
2-Oxocarboxylic acid metabolism
msa01230
Biosynthesis of amino acids
Module
msa_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
msa_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
msa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
Mycsm_02242
00660 C5-Branched dibasic acid metabolism
Mycsm_02242
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Mycsm_02242
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
Mycsm_02242
Enzymes [BR:
msa01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.6 acetolactate synthase
Mycsm_02242
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Paralog
GFIT
Motif
Pfam:
TPP_enzyme_C
TPP_enzyme_M
TPP_enzyme_N
CO_dh
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
AGB22593
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Position
2205345..2207210
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AA seq
621 aa
AA seq
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MSAPTTRPPEQTNGGQPVPAAAKPTPKNGTAQPKRVAPHQLTGAQAVIRSLEELDVDVIF
GIPGGAVLPVYDPLFDSQKLRHVLVRHEQGAGHAASGYAHATGKVGVCMATSGPGATNLV
TPLADAHMDSIPMVAITGQVGRGLIGTDAFQEADISGITMPITKHNFLVRDGDDIPRAIA
EAFHIASSGRPGPVLVDIPKDVLQGQCTFSWPPQIDLPGYKPNTKPHNRQVREAAKLIAA
ARKPVLYVGGGVIRGEATEQLLDLAELTGIPVVTTLMARGAFPDSHPQHMGMPGMHGTVS
AVAALQRSDLLIALGTRFDDRVTGKLDSFAPEAKVIHADIDPAEIGKNRHADVPIVGDVK
AVITDLIEALRKDGTIGSIKIDNWWEYLRGVQSTYPLSYGPQSDGSLSPEYVIETLGKMA
GPDAVYVAGVGQHQMWAAQFIKYENPKTWLNSGGLGTMGFAVPAAMGAKFGRPEAEVWAI
DGDGCFQMTNQELATCAVEGAPIKVAIINNGNLGMVRQWQTLFYAERYSQTDLATHSHRI
PDFVMLAEAMGCVGLRCERAEDVEDVIRQAREINDRPVVIDFIVGADAQVWPMVAAGTSN
DEIQAAKGIRPLFDDPEEGHA
NT seq
1866 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgcaccaaccacgcgaccgccggagcagacgaatgggggtcagcccgtgcctgct
gccgctaagccgacgccgaagaacggcaccgcgcaaccgaaacgcgttgcgccgcaccaa
ctcaccggtgcgcaggccgtaatccgatcactcgaggaactcgacgtcgacgtcatcttc
ggcattcccggcggcgctgtgttgccggtctatgacccgcttttcgactcgcagaagctg
cggcacgtgttggtccgccacgagcagggtgcaggacatgccgccagcggctatgcacac
gccaccggcaaggtcggcgtgtgcatggcgacatcgggtcccggcgccaccaacttggtc
actccgctggccgatgcgcacatggactcgatcccgatggtggcgatcaccggtcaggtc
ggtcgcggactgatcggcaccgacgccttccaggaggccgacatctccggcatcaccatg
ccgatcaccaagcacaacttcctggtccgcgacggcgacgacatcccgcgggcgatcgcc
gaggcattccatatcgcttcgtcgggtcgtcccggtccggtgctcgtcgacatcccgaag
gatgtgctgcagggccaatgcacgttcagctggccgccgcagatcgatctgcccggctac
aagccgaacaccaagccgcacaaccgacaggtccgcgaggccgccaagctgatcgcggcg
gcccgcaagccggtgctctatgtcggcggcggggtgatccgcggcgaggccaccgagcaa
ctgctggatttggccgagctgaccggcatccctgtggtcaccacgctgatggcgcgcggc
gcgtttcccgacagccacccgcagcacatgggcatgccgggcatgcacggcaccgtgtcg
gcggtcgcggcgttgcagcgcagcgatctgctgatcgcgctcggcacccgtttcgacgac
cgcgtgacgggcaagctggattcctttgcgccagaagccaaagtcatccacgccgacatc
gaccccgccgagatcggcaagaaccggcacgccgacgtcccgatcgtcggcgacgtcaag
gccgtcatcaccgatctgatcgaggcgctgcgcaaggacggcaccatcggctcgatcaag
atcgacaactggtgggaatacctgcgcggcgttcagtcgacgtacccgctgagctacggg
ccgcagagcgacggcagcctgtcgccggagtacgtcatcgaaacgcttggcaagatggcc
ggacccgacgccgtgtacgtcgcaggcgttgggcagcaccagatgtgggccgcgcagttc
atcaaatacgagaacccgaagacgtggctgaattccggcggtcttggcaccatgggcttc
gccgttcccgcggcgatgggcgccaagttcggccgcccggaggccgaggtgtgggccatc
gacggcgacggctgcttccagatgaccaaccaggaactggccacgtgtgcggtcgagggc
gcaccgatcaaggtggccatcatcaacaacggcaaccttggcatggtgcggcagtggcag
acgctgttctacgcagagcggtacagccaaacggatctggccacgcactcgcaccgcatc
ccggatttcgtgatgctggccgaggcgatgggctgtgtcggattgcgttgtgagcgcgca
gaagacgtcgaggacgtcatcaggcaggcgcgtgagatcaacgaccggccggtcgtaatc
gacttcatcgtcggcgccgacgcccaggtgtggccgatggtggccgcaggcaccagcaat
gacgagatccaggccgcgaagggcatccgcccgctgtttgacgatcccgaagaagggcac
gcctga
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