Mycobacterium sp. JS623: Mycsm_02257
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Entry
Mycsm_02257 CDS
T02423
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
msa
Mycobacterium sp. JS623
Pathway
msa00290
Valine, leucine and isoleucine biosynthesis
msa00660
C5-Branched dibasic acid metabolism
msa01100
Metabolic pathways
msa01110
Biosynthesis of secondary metabolites
msa01210
2-Oxocarboxylic acid metabolism
msa01230
Biosynthesis of amino acids
Module
msa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
msa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Mycsm_02257
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Mycsm_02257
Enzymes [BR:
msa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Mycsm_02257
4.2.1.35 (R)-2-methylmalate dehydratase
Mycsm_02257
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AGB22605
UniProt:
L0IST1
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All DBs
Position
2220324..2221757
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AA seq
477 aa
AA seq
DB search
MTSVDTPRTMAEKVWADHVVAHGTGKGEAREPDLIYIDLHLIHEVTSPQAFDGLRLNGRT
VRRPDLTIATEDHNVPTVDIDKPIADPISRTQVETLRRNCEEFGIRLHPMGDAEQGIVHI
IGPQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVFATQTLALRPFKTMAVNV
DGQLPPGVSAKDVILAVIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARA
GMVAPDETTFEFLRGRPHAPKGAQWDAAVAAWLALRTDEGAEFDTEVYLDAATLSPFVTW
GTNPGQGVPLSDSVPDPELMFDDAERQSAEKALAYMDLRPGTAMRDIAVDAVFVGSCTNG
RIEDLRVVADVLRGRKVADGVRMLIVPGSMRVRAQAESEGLGEIFTAAGAQWRQAGCSMC
LGMNPDQLSPGERCASTSNRNFEGRQGKGGRTHLVSPAVAAATAVRGKLSSPAELTQ
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgaccagtgtcgacacgccgcgcacgatggccgaaaaggtgtgggccgaccacgtcgtc
gcccacggcacagggaaaggcgaggctcgcgagcccgacctgatctacatcgatctgcac
ctcattcatgaggtgacgagtccgcaggccttcgacgggctccggctcaacggccgcacg
gtgcgcaggccggacctcacgatcgccaccgaggatcacaacgtgccgactgtcgacatc
gacaagccgatcgccgacccgatatcgcgcacacaggtcgagacgttgcgtcgtaattgc
gaagagttcggtatccggttgcatccgatgggtgacgccgagcagggcatcgtgcacatc
atcgggccgcagttgggactgacgcagcccggcatgacggtggtgtgcggcgacagccac
acgtcaacgcacggcgcgttcggtgcactcgcgatgggcatcggcacgtctgaagtcgag
catgtgttcgccacgcagactcttgcgctgcgtccgttcaagaccatggcggtcaacgtg
gacggtcagttgccgcccggagtcagcgcgaaggacgtcatcctcgcggtgattgcgaaa
attggaaccggcgggggacagggtcacgtcatcgaataccgcggcagcgccatcgaatcg
ctctcgatggagggccggatgacgatctgcaacatgagcatcgaagccggagcgcgcgcc
ggcatggtggcgccggacgaaaccacgttcgaatttttgcgcggtcgaccgcatgcaccg
aagggcgcgcaatgggacgcggcggtggccgcatggctggcattgcgcactgacgaaggg
gctgaattcgacaccgaggtgtatctcgacgcggccacgctgagcccgttcgtcacgtgg
ggcaccaaccccgggcagggcgttccgttgtcggattcggttccggaccccgagctgatg
ttcgatgacgccgaacggcagtcagccgaaaaagccttggcgtacatggatcttcggcct
ggcacggcgatgcgtgacatcgcggtggacgccgtcttcgtcgggtcgtgtaccaacggc
aggatcgaggatctgcgcgtcgtcgccgacgttctgcgcggacgcaaggtggccgacgga
gtgcggatgctgatcgtgccgggttcgatgcgcgtgcgcgcacaggccgaatccgaagga
ctcggggagatcttcaccgcggccggtgcgcagtggcgacaagccgggtgctcgatgtgt
cttggaatgaatccagaccagctgtcgccgggcgagcgttgcgcgtcgacatcgaaccga
aatttcgagggcaggcagggcaagggtggtcgcacgcatctggtgtcgcctgcagtcgct
gcggccaccgctgtgcgagggaagctgtcgtcgccggccgagcttactcagtaa
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