Mycobacterium sp. JS623: Mycsm_03865
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Entry
Mycsm_03865 CDS
T02423
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
msa
Mycobacterium sp. JS623
Pathway
msa00300
Lysine biosynthesis
msa00550
Peptidoglycan biosynthesis
msa01100
Metabolic pathways
msa01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
msa00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Mycsm_03865
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Mycsm_03865
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Mycsm_03865
Enzymes [BR:
msa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Mycsm_03865
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Tox-SGS
Motif
Other DBs
NCBI-ProteinID:
AGB24129
UniProt:
L0IYF4
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All DBs
Position
complement(3784186..3785673)
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AA seq
495 aa
AA seq
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MIELTVAQIADIVGGQLVDISPEQAAATRVTGTVEFDSRAVTPGGLFLALPGGRSDGHDF
AVAAVGAGAVAVLAARPVGVPAIVVEPAAARDTSASVLEFDTDGSGAAVLAALARLAAAV
AAELVDGGLTIVGVTGSSGKTSTKDLLAAVLGPLGEVVAPPGSFNNELGHPWTVLRATES
TDYLVLEMSARHPGNIAALAEIAPPSIAVVLNVGTAHLGEFGSREAIAATKAELPQAVPA
SGVVILNADDAAVAAMADKTAARVVRVGRTATADVWADAVTLDALARPRFTLHTASGKID
VALAVHGDHQVSNALCAAAVALECGASLNQVADALAAAGPVSKHRMAVATRGDGVTVIND
AYNANPDSMAAGLKALAAIANEGGQKRRSWAVLGEMAELGDDAISEHDRIGRLAVRLDVS
RLIVVGTGRSMSAMHHGAVMEGSWGAESTMVADADAALALLRAELRATDVVLVKASNAAG
LGALAEALVTEVVRG
NT seq
1488 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgaactgaccgtcgcccagatcgccgacatcgtcggcggtcagctcgtcgacatc
tcgccggagcaggcggcggcgacgcgcgtcaccgggaccgtcgaattcgattcgcgcgca
gtcactcccggcgggctgttcctcgcgctaccggggggccgttccgacggacacgacttc
gcagtggccgcagtgggtgccggcgccgttgcggtactggcagcacggccggtgggggtg
cccgcgatcgtcgtcgaacccgcggccgcccgggacacaagtgccagcgtgctcgagttc
gataccgatggctctggggccgcggtgctcgcggcgctggcgcggctcgcggccgcggtc
gccgcggaactcgtcgacggtgggctgacgatcgtcggggtcaccggctcgtccggcaag
acctcgacgaaggatctgctcgccgcggtgctcggcccgctcggcgaggtcgtcgcaccg
cctggctccttcaacaacgagctcggccacccgtggacggtgctgcgcgcgaccgagtcc
accgattacctcgtgctcgagatgtcggcgcgccatcccggcaacatcgccgcgctggcc
gagatcgcaccaccgtccatcgcggtcgtgctgaacgtcggcaccgcgcacctcggtgag
ttcggttcgagagaggccatcgcggctacgaaagcagaactgccgcaagctgttccggcg
tccggcgtggtgatcctcaacgccgacgacgccgcagtggccgcgatggcggacaagacg
gccgcgcgggtggttcgggtcggccgcaccgccaccgccgacgtatgggccgatgcggtc
accctcgatgcgttggcccggccgcggttcacgctgcacaccgccagcggaaagatagac
gtcgcactggccgtgcacggcgatcatcaggtgtcgaatgcgctgtgcgccgcggccgtc
gccctggaatgtggcgccagcctcaaccaggtggccgacgcgctcgcggccgcgggcccg
gtgtccaaacaccgcatggccgtcgccacccgcggtgacggtgtcacggtcatcaatgac
gcctacaacgccaacccggactccatggcggccgggctgaaggcgctggccgccatcgcc
aacgaaggcggacaaaaacggcgcagctgggccgtgctcggggagatggccgaactcggt
gacgacgcaatatccgagcatgaccgcatcggccggttggcggtgcgattagatgtgtct
cgactcatcgtcgtgggaaccgggaggtctatgagcgccatgcaccacggggcggtgatg
gagggatcgtggggagctgaatcgaccatggtcgccgatgccgacgccgcgctggcattg
ctgcgggccgaactgcgggcaacagatgtggtgctggtgaaagcctcgaacgcggcaggg
ctcggcgcccttgccgaagcactggtcaccgaagtcgttcgcggatga
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