Mycobacterium sp. JS623: Mycsm_05045
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Entry
Mycsm_05045 CDS
T02423
Name
(GenBank) nucleoside-diphosphate-sugar epimerase
KO
K16045
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
msa
Mycobacterium sp. JS623
Pathway
msa00984
Steroid degradation
msa01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
msa00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
Mycsm_05045
Enzymes [BR:
msa01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
Mycsm_05045
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
Mycsm_05045
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Gene cluster
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_10
RmlD_sub_bind
NAD_binding_4
NmrA
Polysacc_synt_2
KR
adh_short
adh_short_C2
NAD_binding_2
Motif
Other DBs
NCBI-ProteinID:
AGB25255
UniProt:
L0J106
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Position
4991673..4992791
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AA seq
372 aa
AA seq
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MLSGMGDATLTTELGRVLVTGGSGFVGANLVTELLDRGHHVRSFDRAPSPLAAHPRLEVL
EGDICDSATVAAAVDGIDTIIHTAAIIDLMGGASVTEEYRKRSFAVNVEGTKNLVHAAQA
AGVKRFVYTASNSVVMGGQRISGGDETLPYTERFNDLYTETKVVAERFVLSQNGVDGLLT
CSIRPSGIWGRGDQTMFRKVFENVIAGHTKVLVGNKNIKLDNSYVHNLIHGFILAAQHLV
PGGSAPGQAYFINDGEPINMFEFSRPVVEACGQPWPKFWVSGRLVKFLMSVWQWFHFRFG
IPKPLLEPLAVERLYLDNYFSIAKAQRDLGYQPLFTTEQAMSECLPYYVDLFHQMKGATP
EHVVVTAAPPAG
NT seq
1119 nt
NT seq
+upstream
nt +downstream
nt
atgctctccggcatgggtgatgcaacgttgaccaccgaactcggccgcgtcctcgtgacc
ggcggctctggcttcgtcggcgccaacttggtgaccgaactgctggaccgcggacaccac
gtccgctcattcgaccgagccccgtccccactcgccgcgcatccgcggctcgaggtcctc
gaaggcgacatctgcgattctgcgaccgtggccgctgccgtcgacggtatcgacacgatc
atccataccgcggcgatcatcgatctgatgggcggcgcctcggtcaccgaggagtaccgc
aagcgcagcttcgcggtcaacgtcgagggcacaaagaacctggtgcatgccgcgcaggcg
gccggggtgaagcggttcgtctacaccgcctccaacagcgtggtgatgggcggtcagcgc
atctccggcggcgacgaaacgctgccctacaccgagcgtttcaacgacctctacaccgag
acgaaagtggttgcggagcggtttgtgttgtcgcagaacggtgttgacggattgttgacg
tgctcgatccggccaagtggcatttggggccgcggcgatcagacgatgttccgcaaggtg
ttcgagaacgtgatcgccggccacaccaaggtgctggtcggcaacaagaacatcaagctc
gataactcctacgtgcacaacctgattcacggcttcatcctggccgcgcagcatctggtg
ccaggcggatccgcgccagggcaggcctacttcatcaacgacggcgagccgatcaacatg
ttcgagttctcgcggccggtggtcgaggcctgcgggcagccgtggccgaagttctgggtg
tccggacgcctggtgaagttcctgatgtcggtgtggcaatggttccacttccgcttcggc
attcccaagcccctgctggaaccgcttgcggtggaacggctttacctcgacaactacttc
tcgatcgccaaggcgcagcgcgaccttgggtatcagccgctgttcaccaccgagcaggcg
atgtcggagtgtctgccgtactacgtcgacctgttccaccagatgaagggtgcgacgccg
gagcacgtcgtggtcacggcagctccgccagcgggctga
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