Micromonospora sagamiensis: GCM10017556_06990
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Entry
GCM10017556_06990 CDS
T06946
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
msag
Micromonospora sagamiensis
Pathway
msag00300
Lysine biosynthesis
msag00550
Peptidoglycan biosynthesis
msag01100
Metabolic pathways
msag01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
msag00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GCM10017556_06990 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GCM10017556_06990 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GCM10017556_06990 (murF)
Enzymes [BR:
msag01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GCM10017556_06990 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BCL12960
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Position
complement(868669..870066)
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AA seq
465 aa
AA seq
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MITLTLAELAAAVDGRLVGADPTATVTGAVEFDSRKVRPGGLFVAFDGEKVDGHDYAARA
VADGAVAVLGTREVPGVPMVLVADALAALGRLARAVVDRLPELTVIGITGSSGKTTTKDL
IAQLTARLGPTVAPPGSFNNELGHPYTALQAGPDTRFLVLEKGARGVGHVRYLCDVVPPR
ISVVLNVGVAHIGEFGSRETIAMAKGELVEALPVDGLAVLNADDPLVAAMATRTRGRVVR
YGEAVDADVRATDVTLDDRGRPSYTLVTPEGAVPVRLGLTGHHQVSNSLAAAAVARELGM
PLADLAEALGGLGLVSTRRMDVFDRPDGVTVIDDSYNANPASMAVALRALAGMRRNGRTI
AVLGYMAELGPFEVDGHREVGRLAAELGVDRLLVVDAAAAPIQAGATAVGNWGGESVLLT
DQAAAVEVLRSELRPGDVVLVKGSRYRTWEVADALRVGTGGEDAQ
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
gtgatcacactgaccctggccgagctggccgccgccgtcgacgggcggctggtcggcgcc
gacccgaccgccacggtgaccggcgcggtcgagttcgactcccgcaaggtccgccccggc
gggctcttcgtcgccttcgacggggagaaggtcgacgggcacgactacgcggcccgcgcg
gtggccgacggcgcggtcgccgtcctcggcacccgggaggtgcccggcgtgccgatggtg
ctggtcgccgacgcgctcgccgcgctgggccggctcgcccgcgccgtggtggaccggctg
ccggaactgaccgtcatcggcatcaccggctcctccggcaagaccaccaccaaggacctg
atcgcccagctcaccgcccggctcggcccgacggtggccccgcccgggtcgttcaacaac
gagctgggacacccgtacacggcgttgcaggcggggccggacacccggttcctggtgctg
gagaagggcgcccgcggggtggggcacgtccgctacctctgcgacgtggtgccaccccgg
atctcggtggtgctcaacgtgggggtggcgcacatcggggagttcggctcccgggagacg
atcgccatggccaagggggaactggtcgaggcactgccggtcgacgggctcgccgtgctc
aacgccgacgacccgctggtcgccgcgatggccacccgcacccggggccgggtggtccgc
tacggcgaggcggtcgacgccgacgtgcgcgccaccgacgtgacgctggacgaccgggga
cgcccctcgtacacgctggtcacgccggagggcgccgtaccggtgcggctcggtctgacc
ggccaccaccaggtctccaactcgctggccgccgcggcggtggcccgggaactgggcatg
cccctggccgacctggccgaggcgctcggtgggctggggctggtctcgacccggcggatg
gacgtcttcgaccgtcccgacggggtgacggtgatcgacgactcgtacaacgccaacccg
gcgtcgatggcggtcgcgctgcgcgcgctggccggcatgcggcggaacgggcggacgatc
gcggtgctcggctacatggccgaactgggcccgttcgaggtcgacgggcaccgggaggtc
ggccggctcgcggccgaactgggtgtcgaccggctgctcgtggtggacgcggcggcggca
ccgatccaagcaggcgcgacagcggtaggaaactggggaggagaatcggtgctgctcacc
gatcaggcagcggccgtcgaggtgctgcgcagtgagctacggccaggggacgtggtcctg
gtcaagggctcccggtaccgcacctgggaggtggccgacgcgctgcgcgtcggcaccggg
ggtgaggacgctcaatga
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