Mycobacteroides salmoniphilum: DSM43276_01795
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Entry
DSM43276_01795 CDS
T06041
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
msal
Mycobacteroides salmoniphilum
Pathway
msal00300
Lysine biosynthesis
msal00550
Peptidoglycan biosynthesis
msal01100
Metabolic pathways
msal01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
msal00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DSM43276_01795 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DSM43276_01795 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DSM43276_01795 (murF)
Enzymes [BR:
msal01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DSM43276_01795 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CPxCG_zf
Motif
Other DBs
NCBI-ProteinID:
QCH23536
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Position
1802343..1803827
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AA seq
494 aa
AA seq
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MIEMTVAEIAEVVGGRLDGIGVDEARNTTVTGTVEFDSRHVGPGGLFLALPGARVDGHDH
AEGAVAAGAVAVLAARPVGVPAIVVSPTGVARTEVSALEHDLDGSGAAVLAATAALAAEV
ARRLTRRGLRIVGVTGSSGKTSTKDLIAAVLNPLGEVVAPPGSFNNELGHPWTVLRASES
TKFLVLELSARRPGNIADLAAIAPPSIGVVLNVGTAHLGEFGSRQAIADTKGELPQSLSN
DGVAVLNADDSAVAAMAAKTQARVVRTSVHNTADIWATEVSVDDLARARFTLHAGDAVVP
VRLAVHGEHQVSNALAAAAVALECGATLAQVADALAGAGPVSRRRMEVSTRDDGVTVIND
AYNANPDSMMAGLKALVSMARHGRESRRSWAVLGEMAELGPDAISEHDRIGRAAVRLDVS
RLVVVGTGRSQRAMHAGAVMEGSWGSEAVLVDDPAAAATLLADELAAGDVVLVKASRSAG
LWVVADELLKAGDA
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atgattgagatgactgtcgccgagatcgccgaggtcgtcggtgggcgtctcgacggaatc
ggtgtcgatgaggcccggaacacgacggttaccggcaccgtcgaattcgactcgcgtcat
gtggggccaggtggactgttcctggccctgccgggtgcccgggtcgatggtcacgatcat
gccgaaggtgccgtcgcggccggtgccgtcgcggtgctggcggccaggccggtgggtgtg
ccagccattgtggtgtcacccaccggcgtcgcgcgcacggaagtgtctgcactggaacat
gatttggacggatcgggtgccgcggtgctggccgcgaccgccgcgctggcagccgaggtg
gcccgacggctcacgcggcgagggctgcgcatcgtcggtgtcaccggctcgtcgggaaag
acgtcgacaaaggacctcatcgccgcggtgctcaacccgctcggtgaggtggtggctcct
cccggatccttcaacaacgagcttggtcacccctggaccgtcctgcgggccagtgaatcg
accaagttcctggtgttggagctgtcagcccgccgtcccggaaacatcgcggacctcgcg
gccatcgcgccgccatcgatcggtgtcgtgctcaatgtcggcacggcacatctgggcgag
ttcggctcgcgacaggccattgccgataccaagggtgaactgccgcagtcgctttcgaat
gacggtgtcgcagtgctgaatgccgatgattccgcggtggccgcgatggccgccaagacg
caggcgcgggtggtgcgcaccagcgtgcacaacaccgctgatatctgggcgaccgaggtg
agcgtcgacgatctggcgcgtgcccgcttcaccctgcatgccggtgacgcggtcgtaccg
gttcggctggctgtgcacggtgagcatcaggtgagcaacgcgttggccgctgccgcggtc
gcgctggaatgcggcgccaccctcgcgcaggttgccgacgctctcgccggggcggggccg
gtgtcgcggcgcaggatggaggtcagtacccgagatgatggggtcaccgtcatcaacgat
gcttataacgccaacccggattcgatgatggccgggctgaaagccctggtctccatggct
cgccatgggcgagaatcccgccgtagctgggcggtgctgggggagatggccgagctgggg
cccgacgcgatatccgagcatgaccgcatcggacgggccgcggtgcgcttagatgtcagt
cgattggtagtcgtcggaaccgggaggtcgcagcgggcaatgcatgcgggtgcagtgatg
gaggggtcgtgggggtccgaggcggtgctggtggacgatcctgcggcagccgccacgctg
ctggccgacgagctggccgcgggcgatgtggtgctggtcaaggcatcgcgatcggccggg
ctatgggttgtagccgatgagctgctgaaggcaggtgacgcatga
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