Mycolicibacterium sediminis: MSEDJ_20410
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Entry
MSEDJ_20410 CDS
T07629
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
msei
Mycolicibacterium sediminis
Pathway
msei00860
Porphyrin metabolism
msei01100
Metabolic pathways
msei01110
Biosynthesis of secondary metabolites
msei01120
Microbial metabolism in diverse environments
msei01240
Biosynthesis of cofactors
Module
msei_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
msei_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
msei00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MSEDJ_20410 (hemD)
Enzymes [BR:
msei01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MSEDJ_20410 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MSEDJ_20410 (hemD)
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GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBY27945
UniProt:
A0A7I7QNT7
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Position
2100381..2102057
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AA seq
558 aa
AA seq
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MERERKMTTRRKHKPGRITFVGSGPGDPGLLTTRARIVLTNAALAFTDPDVPEAVLALIG
TELPPASGPEAPAKSDSDAGPDAGGTTTDATVAVPNGVDVRPALGDPAEVAKILVNEARS
GVDVVRLVSGDPLSVDAVLAEVTAVARAQAHFEIVPGLPATTAVPTYAGLPLGSAHTVAD
VRGDVDWAALAAAPGPLILHATSSHLSDAARTLIEYGLTDTTPCVVTANGTTCQQRSVET
TLAGLLDKATLAGSEPAGPLAGPLVATIGKTVANRAKLNWWESRALYGWTVLVPRTKDQA
GEMSDRLVGHGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEK
FNEFGLDARAFSGVKIACVGQATADRVRAFGINPELVPSGEQSSLGLLDEFPPYDDIFDP
VNRVLLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAQTREMIKTGGFDAVCFT
SSSTVRNLVGIAGKPHARTIVACIGPKTAETAAEFGLRVDVQPETAAVGPLVEALAEHAA
RLRAEGALPPPRKKSRRR
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atggagcgggagcgaaagatgacgacccgacgtaagcacaagcccggccgcatcacgttc
gtgggttccgggccgggggacccaggtctcctgacgacccgggcccgcatcgtgctgacc
aacgccgcgctggcgttcaccgaccccgacgtccccgaggcggtgctcgccctcatcggg
accgagctgccgccggcctcgggtcccgaggcgccggccaagtccgattcggacgcaggc
ccggacgccggtggcacgaccaccgacgcgaccgtggccgtaccgaacggcgtggacgtg
cggcctgccctcggcgaccccgccgaggttgccaagatcctggtcaacgaggcgcgttcc
ggcgtcgacgtcgtccgcctggtctccggtgatccgctgtcggtggacgcggtgctcgcc
gaggtgaccgcggtggcacgggcgcaggcccacttcgagatcgtcccggggctgccggcg
accaccgccgtccccacctacgcgggcctcccgctgggctcggcgcacacggtggccgac
gtccgcggtgacgtcgattgggccgccctggccgccgcgcccggtccgctgatcctgcac
gcgacgtcgtcgcacctctccgacgccgcgcggacgctgatcgagtacggactgaccgac
accacgccgtgcgtcgtcaccgccaacggcaccacctgccagcagcggtcggtcgagacc
acgctggccggcctgctcgacaaggccaccctcgccggcagcgagcccgcgggtccgctc
gcaggcccgctggtcgcgaccatcggcaagaccgtcgccaaccgggcgaagctgaactgg
tgggagagccgcgcactgtacggctggaccgtgctggtgccccggaccaaggatcaggcg
ggcgagatgagcgatcgcctcgtcggccacggcgccctgccgatcgaggtgccgaccatc
gccgtcgagccgccgcgcagccccgcgcagatggagcgtgcggtgaagggtctggtcgac
ggccgcttccagtgggtcgtgttcacctccaccaacgccgttcgcgcggtgtgggagaag
ttcaacgagttcggtctggacgcccgggcgttctccggcgtcaagatcgcctgcgtcgga
caggccaccgcggatcgcgtacgcgcgttcgggatcaaccccgaactcgtgccgtccggt
gagcagtcctcgctggggctgctcgacgagttcccgccctacgacgacatcttcgacccg
gtgaaccgcgtgctgctgccgcgcgcggacatcgccaccgagacgctggccgagggcctg
cgcgagcgcggctgggagatcgaggacgtcaccgcgtaccgcacggtgcgcgcggccccg
cccccggcgcagacccgcgagatgatcaagaccggcggcttcgacgcggtctgcttcacc
tcgagctcgacggtccgcaacctcgtcgggatcgcgggcaagccgcacgcgcgcaccatc
gtcgcgtgcatcgggcccaagaccgccgagaccgcagccgaattcgggctgcgcgtcgac
gtccagccggagacggcggccgtcggcccgctcgtggaggcgctcgccgagcacgccgcc
cggctgcgtgccgagggtgcgctgccgccgccgcgcaagaagagccgtcgccgctag
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