Mycolicibacterium senegalense: K3U95_15435
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Entry
K3U95_15435 CDS
T07649
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
msen
Mycolicibacterium senegalense
Pathway
msen00300
Lysine biosynthesis
msen00550
Peptidoglycan biosynthesis
msen01100
Metabolic pathways
msen01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
msen00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
K3U95_15435
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
K3U95_15435
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
K3U95_15435
Enzymes [BR:
msen01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
K3U95_15435
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PG_isomerase_N
Motif
Other DBs
NCBI-ProteinID:
QZA22169
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Position
complement(3290276..3291829)
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AA seq
517 aa
AA seq
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MIEMTIARIAEIVGGELADIGADEAASTVVTGSVEFDSRAIGPGGLFLALPGARSDGHDF
AAAAVESGAVAVLAARPVGVPAIVVQPDPGAADAASGALEFDTDGSGAAVLAALAKLAAA
VAAELVAGGLTIIGVTGSSGKTSTKDLLAAVLDPLGQVIAPPGSFNNELGHPWTVLRATP
DTDYLILEMSARHPGNIAALAAIAPPQIAVVLNVGTAHLGEFGSREAIANTKAELPQAVP
ASGVVILNVDDTAVAAMAGKTAARVVRVSREPGSEVDVWAGPVTLDELARPRFTLHAGGE
QVDVALAVHGDHQVGNALCAAAVALKCGARLDQVATALAGAGPVSRRRMQVTTRPDGVTV
INDAYNANPDSMRAGLKALAWMARQNARDQAGEPAIDLGGKRRSWAVLGEMAELGDDAIT
EHDAIGRFAVRLDVSRLIVVGTGRTMNAMHHGAVMEGSWGSESTMVDDADAALALLQAEL
QPGDVVLVKASNSVGLGALADALLAAAGPAADGDAVR
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgagatgaccatcgccaggatcgccgagatcgtcggcggcgagttggccgacatc
ggtgccgacgaggccgcctcgaccgtggtcaccggctccgtcgagttcgattcccgtgcg
atcggccccggcggattgttcctggcgttgcccggggcccgttccgacggccatgacttc
gcagcggccgcggtggagtccggggccgtcgccgtgctggccgcccgtccggtcggggtg
cccgcgatcgtcgtacaaccggaccccggggcggccgacgccgcctccggcgctttggaa
ttcgacaccgacggctccggtgcggcggtgctggccgcgctggccaagctggcggctgcg
gtggccgctgaactcgtggcgggcgggttgacgatcatcggggtgacggggtcctcgggc
aagacctcgaccaaggatctgctggccgcggtgctcgacccgctcgggcaggtcatcgca
ccgccgggttcgttcaacaacgagctgggccacccgtggacggtgctgcgggccacgccg
gataccgattacctgatcttggagatgtccgcccggcatccgggcaacatcgccgcgctg
gccgcgatcgctccgccccagatcgcggtggtgctcaacgtgggtaccgcccacctcggc
gagttcggctcgcgcgaggccattgcgaacaccaaagccgagttgccgcaggctgttccg
gcctcaggggtggtgatcctcaacgtagacgacaccgccgtggcggccatggcgggcaag
accgcggcgcgcgtggtgcgggtctctcgcgaacctggttccgaggttgacgtatgggcc
ggcccggtcacgctcgacgagctcgcgcgcccccggttcaccctgcatgcgggcggcgaa
caggtcgacgtggcgttggcggtgcacggtgatcaccaggtcggcaatgctttgtgtgcg
gccgcggtggccctgaagtgcggcgccagattggaccaggtggcgacggcgttggccggc
gcgggcccggtatcgaggcggcggatgcaggtcaccacccgccccgacggtgtgacggtg
atcaacgacgcctacaacgccaatccggattcgatgcgtgccggcctgaaggcgctggcc
tggatggcccgacagaatgcccgtgaccaggcgggtgaacccgccattgacctgggcggg
aagcgccgcagctgggcggtgttgggggagatggccgaactcggtgacgacgcgataacc
gagcacgacgccatcggaaggttcgcggtgcgcttagatgtgtctcggttaatcgtcgtc
ggcaccgggaggactatgaacgccatgcaccacggcgcggtgatggagggttcgtgggga
tctgagtccacgatggtcgatgacgccgatgctgccctggccctgttgcaggctgagctg
cagcccggggacgtggtgctggtgaaggcatccaactcggtcgggttgggcgcgcttgcc
gatgccctgcttgccgcggccggcccggccgcagacggggatgccgttcgatga
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