Mycobacterium senriense: MTY59_08640
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Entry
MTY59_08640 CDS
T10222
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mser Mycobacterium senriense
Pathway
mser00860
Porphyrin metabolism
mser01100
Metabolic pathways
mser01110
Biosynthesis of secondary metabolites
mser01120
Microbial metabolism in diverse environments
mser01240
Biosynthesis of cofactors
Module
mser_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mser_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
Enzymes [BR:
mser01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MTY59_08640 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MTY59_08640 (hemD)
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NCBI-ProteinID:
BCZ21009
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Position
complement(891305..892966)
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AA seq
553 aa
AA seq
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MTTRGRKPTPGRITYVGSGPGDPGLLTTRAATVLANAALVFTDPDVPEPVLALIGKDLPP
VSGPAPAEPAATNGDGGSDQGKTQPAVISGGPDIRPALGDPAEVAKTLTTEARTGVDVVR
LVAGDPLTVDAVITEVNAIARSHLHIEIVPGLAPSDAVPTYAGLPLGSAHTVADVRDPHV
DWEALAAAPGPLILQATSSHLADAARTLIEHELAENTPCVVTAQGTTCQQRSIETTLHGL
TDSAVLGGTDPAGPLIGPLVVTIGKTVANRAKLNWWESRALYGWTVLVPRTKDQAGEMSE
RLTSYGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEFG
LDARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDDFPPYDSIFDPVNRVL
LPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTV
RNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAE
GALPPPRKKSRRR
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgagggcgtaagccgacacccggccgcatcacgtacgtgggctccggcccg
ggtgatccggggctgctgacgacccgggccgccacggtgctggcgaacgccgctttggtg
ttcaccgaccccgacgtgcctgagccggtgctggccctgatcggcaaggacctgccaccg
gtgtccggcccggccccggccgagccggccgccaccaacggcgatggcggttccgaccaa
ggcaagacacagccggcggtgatctccggcggtcccgatatccgcccggcgctgggtgac
cccgccgaggtggccaagacactgaccaccgaggcgcggaccggcgtcgacgtggtgcgg
ctggtggccggcgacccgctgacggtcgacgcggtcatcaccgaggtcaacgccatcgcg
cggagccacttgcacatcgagatcgtgcccgggctggctcccagcgatgccgtcccgacg
tatgcggggctgccgctgggctccgcgcacacggtcgccgacgtgcgcgacccacatgtc
gattgggaagcgctggccgcggcgcccggcccgctgattctgcaggccacgtcgtcgcat
ctggccgacgcggcgcgcaccctgatcgagcacgagctcgccgagaacacgccgtgcgtg
gtgaccgcgcagggcaccacctgtcagcagcgttccatcgagaccacgctgcacggcttg
accgactcggcggtgctgggcggtaccgaccccgccggcccattgatcggtccgctggtg
gtgaccatcggcaagacggtggccaaccgggcgaagctgaattggtgggagagccgcgcg
ttgtacggctggaccgtgctggtgccccgcaccaaggaccaggccggggagatgagcgag
cggctgacgtcctacggcgcgctgccgatcgaggtgccgaccatcgcggtcgagccgccg
cgcagccccgcccaaatggaaagggccgtcaagggtttggtcgacggccgcttccagtgg
gtggtgttcacgtccaccaacgcggtgcgtgcggtgtgggagaagttcggcgagttcggt
ctggacgcgcgcgcgttctccggagtgaagatcgcgtgtgtgggcgagtcgaccgccgac
cgggtccgggcgttcgggatcagccccgaactggtgccggccggcgagcagtcctcactg
ggtctgctcgacgacttcccgccctacgacagcattttcgacccggtcaaccgggtgctg
ctgccgcgcgccgacatcgccaccgagacgctggccgagggtctgcgcgaacgcggttgg
gagatcgaggatgtcaccgcctaccggacggtgcgggccgctccgccgccggcggaaacg
cgggaaatgatcaagaccggtgggttcgacgcggtgtgcttcacgtccagctccacggtg
cgaaacctggtcggcatcgccggcaagccgcacgcacggacgatcatcgcctgcatcggt
cccaagaccgcggagaccgcggctgaattcggtctgcgggtggatgtccagcccgagacc
gccgcggttggcccgctggtcgacgcgctggccgaacacgccgcgcgcttgcgcgccgag
ggtgcgctgccgccgccgcgcaaaaagagccgcaggcgctag
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